Click chemistry in Applications

Copper-catalyzed reaction of an azide with an alkyne to form a 5-membered heteroatom ring, also known as Cu(I)-Catalyzed Azide-Alkyne Cycloaddition (CuAAC), is a powerful reaction for the synthesis of bioconjugates.

Scheme of copper-catalyzed сlick chemistry alkyne azide cycloaddition

Terminal alkyne and azide groups are almost never encountered in natural molecules, so they must be first introduced into the biomolecules to be linked. Alkyne-containing DNA can be prepared with an alkyne phosphoramidite during standard oligo synthesis. Azide or alkyne groups can be attached to proteins by using bifunctional adapter molecules with an NHS ester moiety.

Aqueous DMSO, DMF, acetonitrile, alcohols, or pure water and buffers can be used for the сlick chemistry reaction. The reaction is compatible with a wide range of functional groups.

The following list includes only a few of reagents for сlick chemistry. Please check other categories, especially alkynes and azides.

(S,R,S)-AHPC-PEG2-C2-azide

Degrader building block containing an E3 ligase ligand with linker and azide group, which can be conjugated to alkyne-functionalized linkers and target protein ligands through click chemistry reactions.
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Cat. # Quantity Price Lead time
4530-25mg 25 mg $189 in stock
4530-100mg 100 mg $529 in stock
4530-500mg 500 mg $1598 in stock
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3-Azidopropylamine

Water-soluble, bifunctional short crosslinker with amino and azide groups.
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Cat. # Quantity Price Lead time
58-1g 1 g $145 in stock
58-5g 5 g $490 in stock
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3-Azidopropylamine hydrochloride

A bifunctional short linker with amino and azido groups. A solid, chemically stable hydrochloride form of azidopropylamine. This product is ideal as an azidopropylamine bulk for applications when a large amount of reagent is needed.
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Cat. # Quantity Price Lead time
4003-50g 50 g $5990 in stock
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4AZP (4-Azido-L-phenylalanine)

Unnatural L-phenylalanine derivative with an azide moiety for nascent protein synthesis detection via copper-catalyzed and copper-free click chemistry.
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Cat. # Quantity Price Lead time
3415-100mg 100 mg $125 in stock
3415-500mg 500 mg $625 in stock
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5-Ethynyl-uridine (EU)

Uridine alkyne derivative for monitoring and investigation of RNA transcription in cells.
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Cat. # Quantity Price Lead time
2439-25mg 25 mg $137 in stock
2439-100mg 100 mg $487 in stock
2439-500mg 500 mg $950 in stock
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Ac4GalNAl (N-(4-pentynoyl)-galactosamine-tetraacylated)

An alkyne-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
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Cat. # Quantity Price Lead time
4037-5mg 5 mg $129 in stock
4037-25mg 25 mg $240 in stock
4037-100mg 100 mg $630 in stock
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Ac4GalNAz (N-Azidoacetylgalactosamine-tetraacylated)

An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
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Cat. # Quantity Price Lead time
3706-5mg 5 mg $129 in stock
3706-25mg 25 mg $240 in stock
3706-100mg 100 mg $630 in stock
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Ac4GlcNAl (N-4-pentynoyl-glucosamine-tetraacylated)

An alkyne-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
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Cat. # Quantity Price Lead time
4130-5mg 5 mg $129 in stock
4130-25mg 25 mg $240 in stock
4130-100mg 100 mg $630 in stock
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Ac4GlcNAz (N-Azidoacetylglucosamine-tetraacylated)

An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
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Cat. # Quantity Price Lead time
3662-5mg 5 mg $129 in stock
3662-25mg 25 mg $240 in stock
3662-100mg 100 mg $630 in stock
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Ac4ManNAl (N-(4-pentynoyl)-mannosamine-tetraacylated)

An alkyne-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
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Cat. # Quantity Price Lead time
3431-5mg 5 mg $129 in stock
3431-25mg 25 mg $240 in stock
3431-100mg 100 mg $630 in stock
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Ac4ManNAz (N-Azidoacetylmannosamine-tetraacylated)

An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
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Cat. # Quantity Price Lead time
3159-5mg 5 mg $129 in stock
3159-25mg 25 mg $240 in stock
3159-100mg 100 mg $630 in stock
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AF 343 (Coumarin)-X-azide

AF 343 (Coumarin) is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by сlick chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility and provides spatial separation between the dye and the biomolecule.
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Cat. # Quantity Price Lead time
12630 1 mg $105 in stock
22630 5 mg $165 in stock
42630 25 mg $285 in stock
52630 50 mg $495 in stock
62630 100 mg $880 in stock
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AF 384 (PEP) azide

PEP (phenylethynylpyrene), polyaromatic hydrocarbon fluorescent dye for click-chemistry labeling.
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Cat. # Quantity Price Lead time
A4530 1 mg $110 in stock
B4530 5 mg $210 in stock
C4530 10 mg $310 in stock
D4530 25 mg $410 in stock
E4530 50 mg $695 in stock
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AF 430 alkyne

Alkyne derivative of yellow-green fluorescent dye AF 430 for copper-catalyzed click reaction with azides.
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Cat. # Quantity Price Lead time
A08B0 1 mg $125 in stock
B08B0 5 mg $325 in stock
C08B0 10 mg $480 in stock
D08B0 25 mg $950 in stock
E08B0 50 mg $1625 in stock
F08B0 100 mg $2090 in stock
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AF 430 azide

Azide derivative of AF 430 for labeling and detecting alkyne-containing biomolecules via сlick reaction.
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Cat. # Quantity Price Lead time
A0830 1 mg $125 in stock
B0830 5 mg $325 in stock
D0830 25 mg $950 in stock
E0830 50 mg $1625 in stock
F0830 100 mg $2090 in stock
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AF 488 alkyne

Alkyne derivative of AF 488 dye for copper-catalyzed cycloaddition to azides. Pure 5-isomer.
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Cat. # Quantity Price Lead time
A18B0 1 mg $125 in stock
B18B0 5 mg $325 in stock
D18B0 25 mg $950 in stock
E18B0 50 mg $1625 in stock
F18B0 100 mg $2090 in stock
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AF 488 azide

AF 488 azide is a fluorophore with emission in the green spectrum range. It reacts with alkynes in copper-catalyzed cycloaddition reactions.
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Cat. # Quantity Price Lead time
11830 1 mg $125 in stock
21830 5 mg $325 in stock
41830 25 mg $950 5 days
51830 50 mg $1625 in stock
61830 100 mg $2090 in stock
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AF 555 azide

Azide derivative of yellow fluorescent dye AF 555 for сlick сhemistry.
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Cat. # Quantity Price Lead time
1K830 1 mg $140 in stock
2K830 5 mg $450 in stock
4K830 25 mg $1460 in stock
5K830 50 mg $1890 in stock
6K830 100 mg $2640 in stock
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AF 568 alkyne

AF 568 derivative designed for fluorescence microscopy and flow cytometry. Pure 5-isomer.
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Cat. # Quantity Price Lead time
A48B0 1 mg $140 in stock
B48B0 5 mg $450 in stock
C48B0 10 mg $585 in stock
D48B0 25 mg $1460 in stock
E48B0 50 mg $1890 in stock
F48B0 100 mg $2990 in stock
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AF 568 azide

Azide derivative of water-soluble AF 568 dye for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects. Pure 6-isomer.
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Cat. # Quantity Price Lead time
A5820 1 mg $140 in stock
B5820 5 mg $450 in stock
C5820 10 mg $585 in stock
D5820 25 mg $1460 in stock
E5820 50 mg $1890 in stock
F5820 100 mg $2990 in stock
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AF 594 azide

Azide derivative of water-soluble red-fluorescent dye AF 594 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects. Pure 6-isomer.
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Cat. # Quantity Price Lead time
A7830 1 mg $140 in stock
B7830 5 mg $450 in stock
D7830 25 mg $1460 in stock
E7830 50 mg $1890 in stock
F7830 100 mg $2640 in stock
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AF 647 azide

Bright and photostable azide AF 647 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects.
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Cat. # Quantity Price Lead time
A6830 1 mg $140 in stock
B6830 5 mg $450 in stock
D6830 25 mg $1460 in stock
E6830 50 mg $1890 in stock
F6830 100 mg $2640 in stock
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AHA (L-Azidohomoalanine)

Noncanonical amino acid analog of methionine with an azide moiety for nascent protein synthesis detection via copper-catalyzed and copper-free click chemistry.
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Cat. # Quantity Price Lead time
3799-25mg 25 mg $125 in stock
3799-100mg 100 mg $235 in stock
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Alkyne amidite, hydroxyprolinol

Acetylenic amidite for the incorporation of acetylene groups into oligos.
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Cat. # Quantity Price Lead time
21360
/ 6 mL septum
250 mg $110 in stock
41360
/ 6 mL septum
1 g $390 in stock
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Alkyne CPG 1000A

Controlled pore glass solid support for DNA/RNA synthesis with alkyne modification (pore size 1000 Å) for synthesizing long-modified oligonucleotides with 3'-alkyne modification.
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Cat. # Quantity Price Lead time
15860 100 mg $60 in stock
25860 250 mg $120 in stock
35860 500 mg $230 in stock
45860 1 g $380 in stock
55860 5 g $1450 in stock
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Alkyne CPG modifier 500

Solid support for the synthesis of 3'-modified oligonucleotides with alkyne group for Click Chemistry.
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Cat. # Quantity Price Lead time
12860 100 mg $60 in stock
22860 250 mg $120 in stock
32860 500 mg $230 in stock
42860 1 g $380 in stock
52860 5 g $1450 in stock
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Alkyne dT phosphoramidite

Phosphoramidite modifier for synthesizing oligonucleotides containing alkyne modification in the middle of the chain.
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Cat. # Quantity Price Lead time
1897-100mg 100 mg $330 $195 in stock
1897-1g 1 g $2590 $1250 in stock
1897-5g 5 g $9900 $2850 in stock
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Alkyne dT phosphoramidite

Alkyne dT phosphoramidite is a modifier nucleoside amidite for the synthesis of alkynylated oligonucleotides containing an internal label.
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NO items of this product available in stock but you can submit request for bulk.
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Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.
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Cat. # Quantity Price Lead time
41770 25 mg $110 in stock
51770 50 mg $195 in stock
61770 100 mg $290 in stock
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Alkyne maleimide

Maleimide reagent for the attachment of alkyne functional group to proteins, peptides, and other molecules bearing SH (thiol) groups, including cysteine residues.
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Cat. # Quantity Price Lead time
41780 25 mg $95 in stock
51780 50 mg $175 in stock
61780 100 mg $200 in stock
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Alkyne phosphoramidite, 5'-terminal

Alkyne phosphoramidite for the synthesis of oligonucleotides ready for click chemistry.
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Cat. # Quantity Price Lead time
22260 250 mg $110 in stock
32260 500 mg $210 in stock
42260 1 g $350 in stock
62260 5 g $1290 in stock
82260 10 g please inquire in stock
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Alkyne-PEG2-amine

Diethyleneglycol (PEG2) based bifunctional linker containing amine and alkyne functional groups.
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Cat. # Quantity Price Lead time
2065-1g 1 g $120 in stock
2065-5g 5 g $350 in stock
2065-25g 25 g please inquire 5 days
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Alkyne-PEG2-carboxylic acid

Bifunctional diethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
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Cat. # Quantity Price Lead time
2155-1g 1 g $380 in stock
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Alkyne-PEG2-iodide

Bifunctional reactive crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling, and reactive alkyl iodide group.
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Cat. # Quantity Price Lead time
2136-1g 1 g $450 in stock
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Alkyne-PEG2-NHS ester

Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on diethyleneglycol (PEG2).
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Cat. # Quantity Price Lead time
2219-1g 1 g $450 in stock
2219-5g 5 g $980 in stock
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Alkyne-PEG3-amine

Alkyne-PEG3-amine is a medium-length heterobifunctional linker for conjugation.
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Cat. # Quantity Price Lead time
425-1g 1 g $195 in stock
425-5g 5 g $580 in stock
425-25g 25 g please inquire in stock
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Alkyne-PEG3-carboxylic acid

Bifunctional triethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
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Cat. # Quantity Price Lead time
1743-1g 1 g $490 in stock
1743-5g 5 g $980 in stock
1743-25g 25 g please inquire in stock
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Alkyne-PEG3-iodide

PEG3 with alkyne and iodide functional groups, a reactive and hydrophilic linker for alkylation and click chemistry.
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Cat. # Quantity Price Lead time
2193-1g 1 g $490 in stock
2193-5g 5 g $1150 in stock
2193-25g 25 g please inquire in stock
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Alkyne-PEG3-maleimide

Bifunctional spacer with alkyne and maleimide groups for conjugation of biomolecules.
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Cat. # Quantity Price Lead time
2344-100mg 100 mg $140 in stock
2344-1g 1 g $530 in stock
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Alkyne-PEG3-NHS ester

Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on triethyleneglycol (PEG3).
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Cat. # Quantity Price Lead time
2298-1g 1 g $490 in stock
2298-5g 5 g $980 in stock
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Alkyne-PEG3-OH

Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.
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Cat. # Quantity Price Lead time
418-1g 1 g $95 in stock
418-5g 5 g $280 in stock
418-25g 25 g please inquire in stock
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Alkyne-PEG4-amine

A bifunctional linker molecule containing both terminal alkyne moiety for click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.
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Cat. # Quantity Price Lead time
2025-100mg 100 mg $95 in stock
2025-1g 1 g $390 in stock
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Alkyne-PEG4-carboxylic acid

Bifunctional tetraethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
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Cat. # Quantity Price Lead time
2187-1g 1 g $380 in stock
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Alkyne-PEG4-iodide

Bifunctional reactive PEG4-based crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling and reactive alkyl iodide group.
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Cat. # Quantity Price Lead time
2188-1g 1 g $450 in stock
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Alkyne-PEG4-maleimide

Water soluble, heterobifunctional hydrophilic linker with a length of 14 Å, containing maleimide for thiol labeling, and alkyne for click chemistry. An ideal reagent to attach an alkyne moiety to a protein.
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Cat. # Quantity Price Lead time
2002-100mg 100 mg $150 in stock
2002-1g 1 g $590 in stock
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Alkyne-PEG4-NHS ester

Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on tetraethyleneglycol (PEG4).
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Cat. # Quantity Price Lead time
2409-100mg 100 mg $250 in stock
2409-1g 1 g $790 in stock
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Alkyne-PEG4-phosphoramidite

Alkyne phosphoramidite for conjugation of oligonucleotides with biomolecules.
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Cat. # Quantity Price Lead time
2779-100mg 100 mg $390 in stock
2779-250mg 250 mg $680 in stock
2779-1g 1 g $1640 in stock
2779-5g 5 g please inquire in stock
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AMCA azide

Azide derivative of AMCA fluorescent dye for сlick сhemistry. AMCA is one of the brightest blue fluorescent dyes with large Stoke's shift and high resistance to photobleaching.
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Cat. # Quantity Price Lead time
3605-1mg 1 mg $60 in stock
3605-5mg 5 mg $110 in stock
3605-25mg 25 mg $540 in stock
3605-50mg 50 mg $885 in stock
3605-100mg 100 mg $1050 in stock
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Ascorbic acid

Ascorbic acid is a reducing agent converting copper(II) into a monovalent form that catalyzes the click reaction.
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Cat. # Quantity Price Lead time
12050 10 mg $23 in stock
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ATFB SE (N-Succinimidyl 4-Azidotetrafluorobenzoate)

N-Succinimidyl 4-Azidotetrafluorobenzoate (ATFB SE, ATFB-OSu) is a photo-activatable linker used as a versatile labeling agent for investigating biological receptors.
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Cat. # Quantity Price Lead time
2574-250mg 250 mg $134 in stock
2574-1g 1 g $419 in stock
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ATT 550 azide

Azide derivative of water-soluble yellow-fluorescent dye ATT 550 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects.
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Cat. # Quantity Price Lead time
1C930 1 mg $165 in stock
2C930 5 mg $640 in stock
4C930 25 mg $1640 in stock
5C930 50 mg $2090 in stock
6C930 100 mg $2840 in stock
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ATT 565 azide

Azide derivative of water-soluble orange-fluorescent dye ATT 565 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects. Pure 6-isomer.
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Cat. # Quantity Price Lead time
1A930 1 mg $165 in stock
2A930 5 mg $640 in stock
4A930 25 mg $1640 in stock
5A930 50 mg $2090 in stock
6A930 100 mg $2840 in stock
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ATT 594 azide

Azide derivative of water-soluble red fluorescent dye ATT 594 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects.
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Cat. # Quantity Price Lead time
1B930 1 mg $165 in stock
2B930 5 mg $640 in stock
4B930 25 mg $1640 in stock
5B930 50 mg $2090 in stock
6B930 100 mg $2840 in stock
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ATT 633 azide

Azide derivative of water-soluble far-red fluorescent dye ATT 633 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects.
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Cat. # Quantity Price Lead time
1D930 1 mg $110 in stock
2D930 5 mg $540 in stock
4D930 25 mg $1640 21 days
5D930 50 mg $2090 21 days
6D930 100 mg $2840 21 days
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Azide-PEG2-amine

A diethylene glycol (PEG2) linker with azide and amino groups.
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Cat. # Quantity Price Lead time
2581-1g 1 g $110 in stock
2581-5g 5 g $260 in stock
2581-10g 10 g $390 in stock
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Azide-PEG2-carboxylic acid

Bifunctional diethylene glycol with terminal carboxyl and azido groups.
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2816-250mg 250 mg $230 $199 in stock
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Azide-PEG2-iodide

A bifunctional molecule containing hydrophilic PEG2 with azide and iodide groups.
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Cat. # Quantity Price Lead time
2636-250mg 250 mg $290 in stock
2636-500mg 500 mg $430 in stock
2636-1g 1 g please inquire in stock
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Azide-PEG3-amine

A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)
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Cat. # Quantity Price Lead time
218-1g 1 g $95 in stock
218-5g 5 g $280 in stock
218-25g 25 g please inquire in stock
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Azide-PEG3-azide

Triethylene glycol diazide is a bifunctional crosslinker bearing two azide groups. Suitable for click chemistry.
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Cat. # Quantity Price Lead time
207-1g 1 g $95 in stock
207-5g 5 g $390 in stock
207-25g 25 g please inquire in stock
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Azide-PEG3-carboxylic acid

Bifunctional triethylene glycol with terminal carboxyl and azido groups.
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Cat. # Quantity Price Lead time
2558-1g 1 g $265 in stock
2558-5g 5 g $950 in stock
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Azide-PEG3-chloride

Azide-PEG3-chloride contains a reactive halogen atom and an azide group for click chemistry reaction. It can also serve as a protected amine group equivalent.
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2106-1g 1 g $490 in stock
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Azide-PEG3-iodide

Azide-PEG3-iodide is a bifunctional linker with a highly reactive alkylative halogen functional group and an azido group for click chemistry or Staudinger ligation.
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Cat. # Quantity Price Lead time
2163-1g 1 g $290 in stock
2163-5g 5 g $590 in stock
2163-25g 25 g please inquire in stock
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Azide-PEG3-OH

Azide-PEG3-OH is a bifunctional molecule with an azide group, primary alcohol, and a hydrophilic PEG3 linker in between.
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Cat. # Quantity Price Lead time
1742-1g 1 g $90 in stock
1742-10g 10 g $385 12 days
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Azide-PEG3-tetrazine

A hydrophilic bifunctional linker with azide and tetrazine function groups flanking PEG3 (triethylene glycol) spacer.
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Cat. # Quantity Price Lead time
2798-250mg 250 mg $549 in stock
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Azide-PEG4-amine

PEG4 amine azide is a bifunctional linker with amine and azide functional groups. It is based on a tetraethyleneglycol core. The length of the PEG4 linker is 1.4 nm.
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Cat. # Quantity Price Lead time
1868-1g 1 g $90 in stock
1868-5g 5 g $250 in stock
1868-25g 25 g please inquire in stock
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Azide-PEG4-azide

PEG4 diazide is a homobifunctional linker with two azide groups. It can be used for the synthesis of dimeric molecules with a hydrophilic core by click chemistry.
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Cat. # Quantity Price Lead time
1865-1g 1 g $90 in stock
1865-5g 5 g $250 in stock
1865-25g 25 g $950 in stock
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Azide-PEG4-carboxylic acid

Bifunctional tetraethylene glycol with terminal carboxyl and azido groups.
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Cat. # Quantity Price Lead time
2723-250mg 250 mg $134 in stock
2723-1g 1 g $299 in stock
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Azide-PEG4-hydrazide

A bifunctional reagent containing the azide group and hydrazide function. It reacts with aldehydes and ketones. The azide group can then be coupled with various alkynes via CuAAC reaction.
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Cat. # Quantity Price Lead time
4697-100mg 100 mg $248 in stock
4697-500mg 500 mg $791 in stock
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Azide-PEG4-OH

Azide-PEG4-OH is a bifunctional molecule with an azide group, primary alcohol, and a hydrophilic PEG4 linker in between.
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2472-1g 1 g $140 in stock
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Azide-PEG6-NHS ester

A hydrophilic bifunctional linker with azide and NHS ester function groups flanking PEG6 (hexaethylene glycol).
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Cat. # Quantity Price Lead time
3692-250mg 250 mg $325 5 days
3692-1g 1 g $539 in stock
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Azide-PEG6-OH

Water-soluble heterobifunctional crosslinker with a primary hydroxyl group, alkyne-reactive azide group, and a PEG6 hydrophilic linker.
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Cat. # Quantity Price Lead time
2989-500mg 500 mg $209 in stock
2989-1g 1 g $319 in stock
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BDP® 558/568 alkyne

BDP 558/568 is a borondipyrromethene dye for Cyanine3-channel. This product is a terminal alkyne derivative for copper-catalyzed click chemistry.
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Cat. # Quantity Price Lead time
A74B0 1 mg $125 in stock
B74B0 5 mg $260 in stock
C74B0 10 mg $325 in stock
D74B0 25 mg $510 in stock
E74B0 50 mg $895 in stock
F74B0 100 mg $1490 in stock
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BDP® 558/568 azide

BDP 558/568 is a borondipyrromethene fluorophore with absorption and emission spectra close to Cyanine3. This is an azide derivative for сlick chemistry.
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Cat. # Quantity Price Lead time
17430 1 mg $125 in stock
27430 5 mg $260 in stock
37430 10 mg $325 in stock
47430 25 mg $510 in stock
57430 50 mg $895 in stock
67430 100 mg $1490 in stock
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BDP® 576/589 azide

Azide derivative of BDP 576/589 dye for labeling and detecting alkyne-containing biomolecules via сlick reaction.
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Cat. # Quantity Price Lead time
AG430 1 mg $140 in stock
BG430 5 mg $450 in stock
DG430 25 mg $1460 in stock
EG430 50 mg $1890 in stock
FG430 100 mg $2640 in stock
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BDP® 581/591 alkyne

BDP 581/591 is a borondipyrromethene fluorophore useful for fluorescence polarization assays, microscopy, and two-photon experiments. This alkyne is a derivative for copper-catalyzed click chemistry.
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Cat. # Quantity Price Lead time
A64B0 1 mg $125 in stock
B64B0 5 mg $260 in stock
C64B0 10 mg $325 in stock
D64B0 25 mg $510 in stock
E64B0 50 mg $895 in stock
F64B0 100 mg $1490 in stock
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BDP® 581/591 azide

BDP 581/591 is a relatively hydrophobic borondipyrromethene fluorophore that can be used as a probe for ROS species, or fluorescence polarization tracer. This is an azide derivative for сlick chemistry.
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Cat. # Quantity Price Lead time
16430 1 mg $125 in stock
26430 5 mg $260 in stock
36430 10 mg $325 in stock
46430 25 mg $510 in stock
56430 50 mg $895 in stock
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BDP® 630/650 alkyne

Alkyne dye for copper-catalyzed click chemistry, containing borondipyrromethene fluorophore BDP 630/650 for the red channel.
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Cat. # Quantity Price Lead time
A54B0 1 mg $125 in stock
B54B0 5 mg $260 in stock
C54B0 10 mg $325 in stock
D54B0 25 mg $510 in stock
E54B0 50 mg $895 in stock
F54B0 100 mg $1490 in stock
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BDP® 630/650 azide

BDP 630/650 is a bright borondipyrromethene-based fluorophore for the far red area of the spectrum. It possesses a high extinction coefficient and quantum yield. This is an azide for сlick chemistry labeling.
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Cat. # Quantity Price Lead time
15430 1 mg $125 in stock
25430 5 mg $260 in stock
35430 10 mg $325 in stock
45430 25 mg $510 in stock
55430 50 mg $895 in stock
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BDP® 650/665 alkyne

BDP 650/665 is a bright borondipyrromethene red-emitting dye. The terminal ethynyl group of BDP 650/665 alkyne can be easily conjugated with various azides using a copper-catalyzed click reaction.
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Cat. # Quantity Price Lead time
A84B0 1 mg $125 in stock
B84B0 5 mg $260 in stock
C84B0 10 mg $325 in stock
D84B0 25 mg $510 in stock
E84B0 50 mg $895 in stock
F84B0 100 mg $1490 in stock
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BDP® 650/665 azide

BDP 650/665 is a red-emitting borondipyrromethene dye. This azide derivative can be conjugated with alkynes and cycloalkynes.
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Cat. # Quantity Price Lead time
18430 1 mg $125 in stock
28430 5 mg $260 in stock
38430 10 mg $325 in stock
48430 25 mg $510 in stock
58430 50 mg $895 in stock
68430 100 mg please inquire in stock
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BDP® FL alkyne

Borondipyrromethene dye alkyne for click chemistry. Bright and photostable dye for FAM channel.
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Cat. # Quantity Price Lead time
A14B0 1 mg $125 in stock
B14B0 5 mg $260 in stock
C14B0 10 mg $325 in stock
D14B0 25 mg $510 in stock
E14B0 50 mg $895 in stock
F14B0 100 mg $1490 in stock
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BDP® FL azide

BDP FL is a bright and photostable borondipyrromethene dye for the fluorescein channel. This is a dye azide for сlick сhemistry.
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Cat. # Quantity Price Lead time
11430 1 mg $125 in stock
21430 5 mg $260 in stock
31430 10 mg $325 in stock
41430 25 mg $510 in stock
51430 50 mg $895 in stock
61430 100 mg $1490 in stock
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BDP® R6G alkyne

Terminal alkyne derivative of BDP R6G dye for сlick chemistry. BDP R6G is a borondipyrromethene dye whose absorption and emission spectra are similar to R6G (rhodamine 6G).
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Cat. # Quantity Price Lead time
A44B0 1 mg $125 in stock
B44B0 5 mg $260 in stock
C44B0 10 mg $325 in stock
D44B0 25 mg $510 in stock
E44B0 50 mg $895 in stock
F44B0 100 mg $1490 in stock
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BDP® R6G azide

BDP R6G is a high performance borondipyrromethene fluorophore which is tuned to match excitation and emission channels of R6G dye.
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Cat. # Quantity Price Lead time
1476-1mg 1 mg $125 in stock
1476-5mg 5 mg $260 in stock
1476-10mg 10 mg $325 in stock
1476-25mg 25 mg $510 in stock
1476-50mg 50 mg $895 in stock
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BDP® TMR alkyne

Borondipyrromethene dye for TAMRA channel, with alkyne group for copper-catalyzed click chemistry.
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Cat. # Quantity Price Lead time
A24B0 1 mg $125 in stock
B24B0 5 mg $260 in stock
C24B0 10 mg $325 in stock
D24B0 25 mg $510 in stock
E24B0 50 mg $895 in stock
F24B0 100 mg $1490 in stock
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BDP® TMR azide

Borondipyrromethene dye with azido group. Spectral properties are similar to TAMRA dye. Due to long fluorescence lifetime, BDP TMR is especially useful for fluorescence polarization measurements.
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Cat. # Quantity Price Lead time
12430 1 mg $125 in stock
22430 5 mg $260 in stock
32430 10 mg $325 in stock
42430 25 mg $410 in stock
52430 50 mg $895 in stock
62430 100 mg $1490 in stock
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BDP® TR alkyne

BDP TR is a fluorophore for ROX channel. This borondipyrromethene dye is very bright, and resistant to oxidation.
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Cat. # Quantity Price Lead time
A34B0 1 mg $125 in stock
B34B0 5 mg $260 in stock
C34B0 10 mg $325 in stock
D34B0 25 mg $510 in stock
E34B0 50 mg $895 in stock
F34B0 100 mg $1490 in stock
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BDP® TR azide

BDP TR is a red-emitting fluorophore for the ROX channel. This is an azide for copper-catalyzed and copper-free сlick chemistry conjugation.
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Cat. # Quantity Price Lead time
13430 1 mg $125 in stock
23430 5 mg $260 in stock
33430 10 mg $325 in stock
43430 25 mg $510 in stock
53430 50 mg $895 in stock
63430 100 mg $1490 in stock
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Biotin alkyne

Biotin alkyne is a reactive affinity label which can be attached to biomolecules via click reaction.
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Cat. # Quantity Price Lead time
C37B0 10 mg $135 in stock
D37B0 25 mg $325 in stock
E37B0 50 mg $575 in stock
F37B0 100 mg $1150 in stock
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Biotin-PEG2-alkyne

Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.
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Cat. # Quantity Price Lead time
2546-50mg 50 mg $125 in stock
2546-100mg 100 mg $185 in stock
2546-1g 1 g $990 in stock
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Biotin-PEG2-azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
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Cat. # Quantity Price Lead time
2630-50mg 50 mg $140 in stock
2630-100mg 100 mg $180 in stock
2630-1g 1 g $850 in stock
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Biotin-PEG3-azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
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Cat. # Quantity Price Lead time
C3730 10 mg $125 in stock
D3730 25 mg $220 in stock
E3730 50 mg $325 in stock
F3730 100 mg $450 in stock
K3730 1 g $1420 in stock
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Biotin-PEG4-alkyne

Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.
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Cat. # Quantity Price Lead time
2615-50mg 50 mg $125 in stock
2615-100mg 100 mg $185 in stock
2615-1g 1 g $990 in stock
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Biotin-PEG4-azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
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Cat. # Quantity Price Lead time
2674-50mg 50 mg $140 in stock
2674-100mg 100 mg $180 in stock
2674-1g 1 g $850 in stock
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BTTAA ligand

BTTAA is the newest generation of water-soluble ligands for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that dramatically accelerates reaction rates and suppresses cell cytotoxicity.
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Cat. # Quantity Price Lead time
3253-100mg 100 mg $159 in stock
3253-500mg 500 mg $560 in stock
3253-1g 1 g $990 in stock
3253-5g 5 g please inquire in stock
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C8-Alkyne-dT-CE-phosphoramidite

C8-Alkyne-dT-CE-phosphoramidite is a specialized reagent used in the synthesis of oligonucleotides that incorporates a single dT alkyne group. This compound is particularly valuable for applications involving click chemistry, allowing for efficient conjugation reactions.
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Cat. # Quantity Price Lead time
B5460
/ Easily soluble lyophilised form in 8 mL septum
100 umol $110 in stock
25460
/ Easily soluble lyophilised form in 8 mL septum
250 mg $260 in stock
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Cholesterol-PEG4-azide

Cholesterol derivative with azide group for сlick chemistry conjugation.
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Cat. # Quantity Price Lead time
4340-100mg 100 mg $165 in stock
4340-500mg 500 mg $447 in stock
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Copper(II)-BTTAA complex

A catalyst for copper-catalyzed click reactions in aqueous media. A stable сopper(II) complex with BTTAA which must be converted to copper(I) using reducing agents. The complex can be used to prepare a reaction buffer of any composition.
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Cat. # Quantity Price Lead time
10050 1 mL $80 in stock
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Copper(II)-TBTA complex

A catalyst for click reaction. A stable copper(II) complex which must be converted to monovalent copper(I) in situ using reducing agents. The complex can be used to prepare a reaction buffer of any composition.
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Cat. # Quantity Price Lead time
21050 1.5 mL $75 in stock
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Copper(II)-THPTA catalytic buffer, 1.5x

Ready-to-use catalytic buffer containing сopper(II) and water-soluble THPTA ligand. It is suitable for click chemistry modification of proteins.
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Cat. # Quantity Price Lead time
B5150 1 mL $30 in stock
K5150 10 mL $120 in stock
S5150 50 mL $490 in stock