AHA (L-Azidohomoalanine)

Azides Copper-free click chemistry Click chemistry

Cat. #	Quantity	Price	Lead time
3799-1mg	1 mg	–	in stock
3799-25mg	25 mg	$125	in stock
3799-100mg	100 mg	$235	in stock

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L-Azidohomoalanine (AHA) is a noncanonical amino acid analog of methionine that contains an azide moiety. AHA-labeling is a fast, sensitive, non-toxic, and non-radioactive alternative to the traditional technique for detecting nascent protein synthesis.

AHA is the cell-permeable compound randomly incorporated into synthesizing protein instead of methionine during translation. The resulting azide-labeled full-length proteins can be detected via copper-catalyzed click reaction (with fluorescent or biotin-labeled alkynes) or copper-free click reaction (with cycloalkynes) and used for subsequent microscopic imaging or purification tasks.

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General properties

Appearance:	white to light beige powder
Molecular weight:	180.60
CAS number:	942518-29-8
Molecular formula:	C₄H₉ClN₄O₂
IUPAC name:	(S)-2-Amino-4-azidobutanoic acid
Solubility:	water, DMSO, DMF
Quality control:	NMR ¹H and HPLC-MS (95+%)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	Download
	Product specifications

Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.