Cat. # Quantity Price Lead time
118F0 1 mg $140 in stock
218F0 5 mg $450 in stock
418F0 25 mg $1460 in stock
518F0 50 mg $1890 in stock
618F0 100 mg $2640 in stock
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Dibenzocyclooctyne (DBCO, DBCO, ADIBO) is one of the most reactive cycloalkynes for copper-free click reaction (SPAAC, strain-promoted azide-alkyne cycloaddition). The rate of interaction of DBCO with azides is significantly higher than that of other cyclooctynes, as well as Cu-catalyzed click reaction (CuAAC). Unlike other cyclooctynes, DBCO does not interact with tetrazines, which makes it possible to use it in bioorthogonal reactions together with trans-cyclooctenes and tetrazines.

AF 488 is sulfonated rhodamine, a bright, photostable, and hydrophilic fluorophore that emits in the green channel. The absorption maximum is 495 nm. The emission maximum is 519 nm.

AF 488 DBCO allows fluorescent labeling of azide-containing biomolecules inside living cells, whole organisms, and inanimate samples.

Absorption and emission spectra of AF 488

Absorption and emission spectra of AF 488

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AF 555 NHS ester

AF 555 NHS ester, a bright, photostable, and hydrophilic fluorescent dye for the yellow channel.

General properties

Appearance: orange solid
Molecular weight: 936.08
Molecular formula: C48H49N5O11S2
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 495
Emission maximum, nm: 519
Fluorescence quantum yield: 0.91

Product citations

  1. Xia, Q.; Perera, H.A.; Bolarinho, R.; Piskulich, Z.A.; Guo, Z.; Yin, J.; He, H.; Li, M.; Ge, X.; Cui, Q.; Ramström, O.; Yan, M.; Cheng, J.-X. Click-free imaging of carbohydrate trafficking in live cells using an azido photothermal probe. bioRxiv, 2024, preprint. doi: 10.1101/2024.03.08.584185
  2. Xu, W.; He, M.; Lu, Q. Fibronectin Connecting Cell Sheet Based on Click Chemistry for Wound Repair. Advanced Science, 2024, 11(11), 2306746. doi: 10.1002/advs.202306746
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