Isotopically labeled standards and controls for MS/MS

Isotopically labeled standards and controls for MS/MS / product groups & items in this category
Compounds containing stable isotopes can be used as quantitative standards in quantitative LCMS/MS analysis, especially in complex matrices of biological origin.

MS/MS controls

Tandem mass spectrometry controls.
  • (C0) Сarnitine
    Carnitine is an analogue of a natural amino acid, of high chemical purity, and can be used as an analyte for constructing calibration graphs.
  • (C10) Decanoylcarnitine
    Decanoylcarnitine is used as an analytical reference standard using GC- or LC-MS methods.
  • (C12) Dodecanoylcarnitine
    Dodecanoylcarnitine chloride, also referred to as lauroyl-L-carnitine chloride, is used as a control for chromatographic mass spectrometry methods MS/MS.
  • (C14) Tetradecanoylcarnitine
    Myristoyl-L-carnitine may be used as an analytical standard for high-performance liquid chromatography or LC MS/MS studies.
  • (C16) Hexadecanoylcarnitine
    Palmitoyl-L-carnitine is used as an analytical standard in HPLC-MS and MS/MS studies.
  • (C18) Octadecanoylcarnitine
    Stearoyl-L-carnitine for use as an analytical reference standard for MS/MS.
  • (C2) Acetylcarnitine
    Acetyl-L-carnitine is a short-chain acylcarnitine that is used as a control for MS/MS.
  • (C3) Propionylcarnitine
    The acylcarnitine C3 (propionylcarnitine) level along with C3/C2 ratio is used as a diagnostic marker to evaluate metabolism disorders.
  • (C4) Butyrylcarnitine
    An analytical reference standard for the separation and identification of underivatized butyryl-L-carnitine using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS).
  • (C5) Isovalerylcarnitine
    Isovalerylcarnitine chloride is an analogue of endogenous short-chain acylcarnitine and can be used as a control in MS/MS.
  • (C5DC) Glutarylcarnitine
    (C5DC) Glutarylcarnitine chloride is an endogenous metabolite, an ester of carnitine and glutaric acid.
  • (C6) Hexanoylcarnitine
    Hexanoylcarnitine is an organic endogenous compound made from fatty acid and carnitine, a representative of medium-chain acylcarnitines.
  • (C8) Octanoylcarnitine
    Octanoylcarnitine, a representative of medium-chain acylcarnitines, an ester of a saturated fatty acid (octanoic acid) and the amino acid carnitine.
  • C26:0-lysophosphatidylcholine (LPC)
    Lysopc(26:0), also known as LysoPC a C26:0, is used as internal standard LC-MS studies.
  • L-Arginine
    The L-enantiomer of the basic alpha amino acid arginine, of high chemical purity, can be used as a control for mass spectroscopy.
  • L-Citrulline
    L-Citrulline is a non-proteinogenic alpha amino acid that can be used as a control in gas chromatography-mass spectrometry or in the standard addition method.
  • Succinylacetone
    Control for chromatography with tandem mass spectrometry for assessment of concentrations in biological samples.

Isotopically labeled carnitine standards

Isotope-labeled carnitines and acylcarnitines in high chemical purity for labeling biomolecules.
  • (C0) L-Carnitine-d9
    L-isomeric form of carnitine, labeled with deuterium for studies using mass spectrometry.
  • (C10) Decanoyl-L-carnitine-d3
    Decanoyl-L-carnitine-d3 is deuterium labeled decanoyl-L-carnitine, it can be used as an internal standard for the quantification of decanoylcarnitine, decenoylcarnitine, decadienoylcarnitine using GC- or LC-MS methods.
  • (C12) Dodecanoyl-L-carnitine-d3
    Deuterium labeled Lauroyl-L-carnitine used as an internal standard utilized in the measurement of lauroyl-L-carnitine through GC- or LC-MS methods.
  • (C14) Tetradecanoyl-L-carnitine-d3
    Tetradecanoyl-L-carnitine-d3 is deuterium labeled myristoyl-L-carnitine and intended for use as an internal standard for the quantification by GC- or LC-MS.
  • (C16) Hexadecanoyl-L-carnitine-d3
    Deuterated ester of L-carnitine and palmitic acid, intended for use as an internal standard for the quantification of palmitoyl-L-carnitine by GC- or LC-MS.
  • (C18) Octadecanoyl-L-carnitine-d3
    Deuterium-labeled octadecanoyl-L-carnitine is the standard for MS/MS quantitation of carnitine derivatives.
  • (C2) Acetyl-L-carnitine-(N-methyl-d3)
    Isotopically labeled acetylated d3-carnitine, C2 Carnitine-d3, is used for MS imaging and quantitative measurements.
  • (C26) Carnitine-d3
    (C26) Carnitine-d3 is a deuterium labeled (C26) Carnitine and intended for use as an internal standard in GC- or LC-MS.
  • (C26) D,L-Carnitine
    (C26) D,L-Carnitine is a very long chain fatty-acylcarnitine also known as o-hexacosanoylcarnitine and intended for use as an internal standard in GC- or LC-MS.
  • (C3) Propionyl-L-carnitine-(N-methyl-d3)
    C3 Carnitine-d3 is a labeled with stable isotop of carnitine derivative is used for tracking of carnitine and metabolic studies by mass spectrometry (MS).
  • (C4) Butyryl-L-carnitine-(N-methyl-d3)
    C4 Carnitine-d3, deuterated butyrate ester of carnitine used as stable isotope labeled internal standards for quantitative applications.
  • (C5) Isovaleryl-L-carnitine-(trimethyl-d9)
    Deuterium-labeled isovaleryl-L-carnitine is the standard for MS/MS quantitation of carnitine derivatives.
  • (C5DC) Glutaryl-L-carnitine-d6
    Glutaryl-L-carnitine-d6 chloride contains an isotopic label to be used as an internal standard for tandem mass spectrometry.
  • (C6) Hexanoyl-L-carnitine-d3
    C6-Carnitine-d3 is one of the derivatives of the L-isomer of hexanoylcarnitine, labeled with stable isotopes.
  • (C8) Octanoyl-L-carnitine-d3
    Deuterated octanoyl-L-carnitine is used as an internal standard for the quantification of octanoyl-L-carnitine by GC or LC-MS.

Isotopically labeled amino acid standards

Isotope-labeled amino acids in high chemical purity for mass spectrometry.
  • D,L-Arginine-d3
    D,L-Arginine-d3 is a labeled with stable isotop arginine, used in studies by mass spectrometry (MS).
  • D,L-Glutamic acid-d3
    D,L-Glutamic-2,4,4-d3 acid is a deuterium-labeled amino acid used as a standard for quantification of glutamic acid and glutamine by chromatographic methods with tandem mass spectrometry.
  • L-Citrulline-d2
    L-Citrulline-d2, deuterated citrulline used as stable isotope labeled internal standard for quantitative applications.
  • L-Leucine-d3
    L-Leucine-5,5,5-d3 is the deuterium labeled amino acid L-Leucine.
  • L-Methionine (S-methyl-d3)
    L-Methionine-d3 is the deuterium labeled amino acid L-methionine.
  • L-Ornithine-d2
    Deuterated L-Ornithine used as stable isotope labeled internal standard for quantitative applications.
  • L-Phenylalanine (ring-d5)
    L-Phenylalanine-d5 is a stable isotope of amino acid phenylalanine.
  • L-Tyrosine (ring-d4)
    L-Tyrosine-d4, deuterated amino acid tyrosine with a phenyl ring.

Isotopically labeled vitamin standards

Isotope-labeled vitamins for the quantitative analysis based on liquid chromatography - tandem mass spectrometry (LC-MS/MS).
  • Retinol-d5
    Retinol-d5 is a biologically active form of fat-soluble vitamin A, with a stable deuterium label for quantitative studies by MS methods.
  • alpha-Tocopherol-d6
    alpha-Tocopherol-d6 is a deuterated form of vitamin E for mass spectrometry.

Isotopically labeled hormone standards

Isotope-labeled hormones used in metabolic research.
  • 21-Deoxycortisol-d4
    21-Deoxycortisol-(9,11,12,12)-d4 is the deuterium labeled 21-deoxycortisol intended for use as an internal standard utilized in the measurement of 21-Deoxycortisol through GC- or LC-MS methods.
  • 3-O-Methyldopa-d3 (3-OMD-d3)
    3-O-Methyldopa-d3 is deuterated 3-Methoxy-L-tyrosine. The reagent is intended for use as an internal standard for the quantitative determination of 3-Methoxy-L-tyrosine by MS/MS.
  • 5α-Dihydrotestosterone-d3
    Stable isotope labeled 5α-dihydrotestosterone for use as an internal standard by tandem mass spectrometry (MS/MS) methods.
  • Androstenedione-d7
    Androstenedione-d7 is a deuterium-labeled androstenedione and is intended for use as an analytical reference standard in GC- or LC-MS.
  • Estradiol-d3
    Estradiol-d3 is the deuterium labeled estradiol, intended for use as an internal standard for the quantification of estradiol by GC- or LC-MS.
  • Melatonin-d3
    Melatonin-d3 is a deuterium-labeled primary pineal gland hormone, melatonin.
  • Pregnenolone-d4
    Pregnenolone-d4 is the deuterium labeled pregnenolone and used as an internal standard utilized in the measurement of pregnenolone through GC- or LC-MS methods.
  • Progesterone-d9
    Progesterone-d9 is the deuterium labeled progesterone and intended for use as an internal standard for quantification of progesterone through GC- or LC-MS methods.
  • Serotonin-d4
    Serotonin-d4 is deuterium labeled serotonin and intended for use as an internal standard for the quantification of serotonin by GC- or LC-MS.
  • Testosterone-d3
    Testosterone-d3 is an analytical reference standard for the quantification of testosterone by GC- or LC-MS.
  • Сortisol-d4
    Cortisol-d4 (Hydrocortisone-d4) is deuterated cortisol and intended for use as an internal standard for the quantification of hydrocortisone/cortisol by GC- or LC-MS.
  • 3-(5-methyl-1H-pyrazol-3-yl)propionic acid-d6 (MPP)
    Succinylacetone reference standard, stable isotope-labeled succinylacetone (SUAC).
  • Adenosine-d2
    Adenosine-d2 is the deuterium labeled Adenosine and intended for use as an internal standard for the quantification of adenosine by HPLC and LC-MS methods. Adenosine-d2 is commonly used as a tracer in studies related to adenosine receptors and adenosine signaling pathways.
  • Caffeine-d3
    Caffeine-d3 is deuterated caffeine and intended for use as an internal standard for the quantification of caffeine by GC- or LC-MS.
  • Coenzyme Q10-d6
    Coenzyme Q10-d6 is a fat-soluble benzoquinone with a stable deuterium tag, is suitable for use as an internal standard for the quantification of CoQ10 by GC- or LC-MS.
  • Pyrene-d10
    Pyrene-d10 is a deuterated analog of pyrene, valuable in quantitative analysis through techniques such as gas chromatography-mass spectrometry (GC-MS).
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