Mass spectrometry reagents

Mass spectrometry reagents / product groups & items in this category
Products for mass spectrometry. Compounds containing stable isotopes to be used as quantitative standards in LCMS/MS analysis.

Isotopically labeled hormone standards

Isotope-labeled hormones used in metabolic research.
    • Melatonin-d3
      Melatonin-d3 is a deuterium-labeled primary pineal gland hormone, melatonin.
    • Testosterone-d3
      Testosterone-d3 is an analytical reference standard for the quantification of testosterone by GC- or LC-MS.
    • Estradiol-d3
      Estradiol-d3 is the deuterium labeled estradiol, intended for use as an internal standard for the quantification of estradiol by GC- or LC-MS.
    • Сortisol-d4
      Cortisol-d4 (Hydrocortisone-d4) is deuterated cortisol and intended for use as an internal standard for the quantification of hydrocortisone/cortisol by LC-MS.
    • 5α-Dihydrotestosterone-d3
      Stable isotope labeled 5α-dihydrotestosterone for use as an internal standard by tandem mass spectrometry (MS/MS) methods.
    • Pregnenolone-d4
      Pregnenolone-d4 is the deuterium labeled pregnenolone and used as an internal standard utilized in the measurement of pregnenolone through LC-MS methods.
    • Serotonin-d4
      Serotonin-d4 is deuterium labeled serotonin and intended for use as an internal standard for the quantification of serotonin by LC-MS.
    • Androstenedione-d7
      Androstenedione-d7 is a deuterium-labeled androstenedione and is intended for use as an analytical reference standard in LC-MS.
    • 21-Deoxycortisol-d4
      21-Deoxycortisol-(9,11,12,12)-d4 is the deuterium labeled 21-deoxycortisol intended for use as an internal standard utilized in the measurement of 21-Deoxycortisol through LC-MS methods.
    • Progesterone-d9
      Progesterone-d9 is the deuterium labeled progesterone and intended for use as an internal standard for quantification of progesterone through GC- or LC-MS methods.
    • 11-Deoxycortisol-d5
      11-Deoxycortisol-d5 (2,2,4,6,6-d5) is the deuterium-labeled 11-deoxycortisol and is intended for use as an analytical reference standard in GC- or LC-MS.
    • Deoxycorticosterone-d8
      Deoxycorticosterone-d8 is the deuterium-labeled deoxycorticosterone for use as an internal standard for the quantification of deoxycorticosterone by LC-MS.
    • Cortisone-d8
      Cortisone-d8 is a deuterated form of the cortisone and is intended for use as an internal standard for the quantification of cortisone by GC- or LC-MS.
    • 17α-Hydroxyprogesterone-d8
      A deuterium labeled 17α-hydroxyprogesterone for use as an internal standard utilized in the measurement of 17α-hydroxyprogesterone through GC- or LC-MS methods.

Isotopically labeled vitamin and cofactor standards

Isotope-labeled vitamins for the quantitative analysis based on liquid chromatography - tandem mass spectrometry (LC-MS/MS).
    • Retinol-d5
      Retinol-d5 is a biologically active form of fat-soluble vitamin A, with a stable deuterium label for quantitative studies by MS methods.
    • α-Tocopherol-d6
      alpha-Tocopherol-d6 is a deuterated form of vitamin E for mass spectrometry.
    • Coenzyme Q10-d6
      Coenzyme Q10-d6 is an isotopically labeled MS/MS standard for the quantification of CoQ10 by LC-MS.
    • Methylcobalamin-d3
      Methylcobalamin-d3, or Mecobalamin-d3, is a deuterated form of methylated vitamin B12.

Isotopically labeled amino acid standards

Isotope-labeled amino acids in high chemical purity for mass spectrometry.
    • L-Leucine-d3
      L-Leucine-5,5,5-d3 is the deuterium labeled amino acid L-Leucine.
    • L-Tyrosine (ring-d4)
      L-Tyrosine-d4, deuterated amino acid tyrosine with a phenyl ring.
    • L-Phenylalanine (ring-d5)
      L-Phenylalanine-d5 is a stable isotope of amino acid phenylalanine.
    • L-Methionine (S-methyl-d3)
      L-Methionine-d3 is the deuterium labeled amino acid L-methionine.
    • D,L-Arginine-d3
      D,L-Arginine-d3 is a labeled with stable isotop arginine, used in studies by mass spectrometry (MS).
    • L-Citrulline-d2
      L-Citrulline-d2, deuterated citrulline used as stable isotope labeled internal standard for quantitative applications.
    • L-Ornithine-d2
      Deuterated L-Ornithine used as stable isotope labeled internal standard for quantitative applications.
    • D,L-Glutamic acid-d3
      D,L-Glutamic-2,4,4-d3 acid is a deuterium-labeled amino acid used as a standard for quantification of glutamic acid and glutamine by chromatographic methods with tandem mass spectrometry.
    • L-Alanine-d3
      L-Alanine-d3 is the deuterium-labeled L-alanine and is intended for use as an analytical reference standard in LC-MS.
    • Glycine-d2
      Glycine-d2 is the deuterium-labeled glycine and is intended for use as an internal standard for the quantification of glycine by LC-MS.
    • 3-O-Methyldopa-d3 (3-OMD-d3)
      3-O-Methyldopa-d3 is deuterated 3-Methoxy-L-tyrosine. The reagent is intended for use as an internal standard for the quantitative determination of 3-Methoxy-L-tyrosine by MS/MS.

Isotopically labeled carnitine standards

Isotope-labeled carnitines and acylcarnitines in high chemical purity for labeling biomolecules.
    • 3-(5-methyl-1H-pyrazol-3-yl)propionic acid-d6 (MPP)
      Isotopically labeled compound for the quantification of succinylacetone after hydrazine derivatization.
    • Adenosine-d2
      Adenosine-d2 is the deuterium labeled Adenosine and intended for use as an internal standard for the quantification of adenosine by HPLC and LC-MS methods. Adenosine-d2 is commonly used as a tracer in studies related to adenosine receptors and adenosine signaling pathways.
    • Caffeine-d3
      Caffeine-d3 is deuterated caffeine and intended for use as an internal standard for the quantification of caffeine by GC- or LC-MS.
    • Pyrene-d10
      Pyrene-d10 is a deuterated analog of pyrene, valuable in quantitative analysis through techniques such as gas chromatography-mass spectrometry (GC-MS).
    • 2′-Deoxyadenosine-d2
      2′-Deoxyadenosine-d2 is a deuterated form of the nucleoside 2′-deoxyadenosine and is intended for use as an internal standard for the quantification of deoxyadenosine by LC-MS.
    • C26:LPC IS (C26:0-lysophosphatidylcholine-d4)
      C26:0-lysophosphatidylcholine-d4 is deuterated C26:0-lysophosphatidylcholine (Lysopc(26:0)) and intended for use as an internal standard for the quantification of C26:0-lysophosphatidylcholine by GC- or LC-MS.
    • Orotic acid (1,3-15N2) monohydrate
      Orotic acid-1,3-15N2 (monohydrate) is a stable isotope labeled orotic acid for use as an internal standard in GC- or LC-MS.

MS/MS controls

Tandem mass spectrometry controls corresponding to natural analytes without isotopic labels.
    • Succinylacetone
      Control for chromatography with tandem mass spectrometry for assessment of concentrations in biological samples.
    • (C10) Decanoylcarnitine
      Decanoylcarnitine is used as an analytical reference standard using GC- or LC-MS methods.
    • C26:0-lysophosphatidylcholine (LPC)
      Lysopc(26:0), also known as LysoPC a C26:0, is used as internal standard LC-MS studies.
    • (C2) Acetylcarnitine
      Acetyl-L-carnitine is a short-chain acylcarnitine that is used as a control for MS/MS.
    • (C18) Octadecanoylcarnitine
      Stearoyl-L-carnitine for use as an analytical reference standard for MS/MS.
    • (C16) Hexadecanoylcarnitine
      Palmitoyl-L-carnitine is used as an analytical standard in HPLC-MS and MS/MS studies.
    • (C14) Tetradecanoylcarnitine
      Myristoyl-L-carnitine may be used as an analytical standard for high-performance liquid chromatography or LC MS/MS studies.
    • (C12) Dodecanoylcarnitine
      Dodecanoylcarnitine chloride, also referred to as lauroyl-L-carnitine chloride, is used as a control for chromatographic mass spectrometry methods MS/MS.
    • (C8) Octanoylcarnitine
      Octanoylcarnitine, a representative of medium-chain acylcarnitines, an ester of a saturated fatty acid (octanoic acid) and the amino acid carnitine.
    • L-Arginine
      The L-enantiomer of the basic alpha amino acid arginine, of high chemical purity, can be used as a control for mass spectroscopy.
    • (C0) Сarnitine
      Carnitine is an analogue of a natural amino acid, of high chemical purity, and can be used as an analyte for constructing calibration graphs.
    • (C6) Hexanoylcarnitine
      Hexanoylcarnitine is an organic endogenous compound made from fatty acid and carnitine, a representative of medium-chain acylcarnitines.
    • (C5DC) Glutarylcarnitine
      (C5DC) Glutarylcarnitine chloride is an endogenous metabolite, an ester of carnitine and glutaric acid.
    • (C5) Isovalerylcarnitine
      Isovalerylcarnitine chloride is an analogue of endogenous short-chain acylcarnitine and can be used as a control in MS/MS.
    • (C4) Butyrylcarnitine
      An analytical reference standard for the separation and identification of underivatized butyryl-L-carnitine using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS).
    • (C3) Propionylcarnitine
      The acylcarnitine C3 (propionylcarnitine) level along with C3/C2 ratio is used as a diagnostic marker to evaluate metabolism disorders.
    • L-Citrulline
      L-Citrulline is a non-proteinogenic alpha amino acid that can be used as a control in gas chromatography-mass spectrometry or in the standard addition method.
    • (C26) D,L-Carnitine
      (C26) D,L-Carnitine is a very long chain fatty-acylcarnitine also known as o-hexacosanoylcarnitine and intended for use as an internal standard in GC- or LC-MS.

MALDI matrices

Highly purified components for matrix assisted laser desorption ionization (MALDI) mass spectrometry.
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