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Oligonucleotide synthesis reagents

Oligonucleotide synthesis reagents / product groups & items in this category
Reagents for oligonucleotide synthesis.

FAM amidites and supports

Fluorescein phosphoramidites and supports used in solid phase oligo synthesis for introducing terminal modifications or labeling with FAM in the middle of oligonucleotide sequence.
Group tags Oligonucleotide synthesis, FAM (Fluorescein), Phosphoramidites, CPG modifier solid supports

Cyanine phosphoramidites

Cyanine dyes phosphoramidites to incorporate fluorescent label in 5’-terminus of a desirable sequence.
Group tags Oligonucleotide synthesis, Cyanine5, Phosphoramidites, Cyanine5.5, Cyanine3

Xanthene amidites and supports (except FAM)

Xanthene dyes phosphoramidite reagents suitable for oligonucleotide labeling.
Group tags Oligonucleotide synthesis, TET (Tetrachlorofluorescein), HEX (Hexachlorofluorescein), VIC, Phosphoramidites, TAMRA (TMR, Tetramethylrhodamine), JOE, R6G, SIMA (Dichloro-diphenyl-fluorescein)

Quencher phosphoramidites and supports

Solid-phase carriers modified with fluorescence quenchers and phosphoramidites for labeling at both internal and end positions of the oligonucleotide.
Group tags Oligonucleotide synthesis, DusQ 1, DusQ 2, DusQ 3, Phosphoramidites, DusQ 21, CPG modifier solid supports
  • DusQ 1 CPG 1000
    Controlled pore glass (CPG) 1000 solid support for synthesis of oligonucleotides with 3’-terminal DusQ1 quencher. Compatible with standard deblocking conditions.
  • DusQ 1 CPG 500
    Controlled pore glass (CPG) 500 solid support for the synthesis of oligonucleotides with 3’-terminal DusQ 1 quencher. Compatible with standard deblocking conditions.
  • DusQ 1 amidite, 5'-terminal
    Terminal phosphoramidite for labeling oligonucleotides at the 5' end with DusQ 1 quencher.
  • DusQ 1 dT phosphoramidite
  • DusQ 1 phosphoramidite
  • DusQ 2 CPG 1000
    Controlled pore glass (CPG) 1000 modified support for the synthesis of oligonucleotides with DusQ 2 quencher at the 3’ end. Compatible with standard deblocking conditions.
  • DusQ 2 CPG 500
    Controlled pore glass (CPG) 500 modified support for the synthesis of oligonucleotides with DusQ 2 quencher at the 3’ end. Compatible with standard deblocking conditions.
  • DusQ 2 dT phosphoramidite
  • DusQ 2 phosphoramidite
    DusQ 2 is a black quencher dye phosphoramidite for the synthesis of dual-labeled probes. Useful for HEX, JOE, ROX, Cyanine5, and other dyes.
  • DusQ 21 CPG 500
    DusQ 21 is a quencher for dyes in red part of the spectrum, including Cyanine5 and Cyanine5.5.
  • DusQ 3 CPG 500
    DusQ 3 is a dark quencher for far red and near infrared dyes like Cyanine5.5. This is a controlled pore glass solid support for the synthesis of oligonucleotides with the quencher attached to 3'-terminus.

Universal solid supports

Non-nucleosidic controlled pore glass (CPG) support with universal linkers for the solid phase oligonucleotide automated synthesis of the sequence with any nucleoside at 3'-terminus.
Group tags Oligonucleotide synthesis, CPG modifier solid supports
  • Universal CPG type I, 500A
    This universal support is intended for automated synthesis of oligonucleotides without the 3’ terminus modifications under harsh deblock conditions and extended cleavage times. Pore size of 500 Å is recommended for the synthesis of oligonucleotides up to 50 bases in length.
  • Universal CPG type II, 1000A
    This universal support is intended for automated synthesis of oligonucleotides to accelerate the dephosphorylation process during deblocking. Pore size of 1000 Å is recommended for the synthesis of oligonucleotides up to 120 bases.
  • Universal CPG type II, 500A
    This universal support is intended for automated synthesis of oligonucleotides for short-term dephosphorylation process during deblocking. Pore size of 500 Å is recommended for the synthesis of oligonucleotides up to 50 bases.

Click chemistry amidites and supports

Group tags Oligonucleotide synthesis, Copper-free click chemistry, Alkynes, Click chemistry, Phosphoramidites, CPG modifier solid supports
  • Alkyne CPG 1000A
    Controlled pore glass solid support for DNA/RNA synthesis with alkyne modification (pore size 1000 Å) for the synthesis of long modified oligonucleotides with 3'-alkyne modification.
  • Alkyne CPG modifier 500
    Solid support for the synthesis of 3'-modified oligonucleotides with alkyne group for Click Chemistry.
  • Alkyne Phosphoramidite, 5'-terminal
    Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.
  • Alkyne amidite, hydroxyprolinol
    Acetylenic amidite for the incorporation of acetylene groups into oligos.
  • Alkyne dT phosphoramidite
    Phosphoramidite modifier for the synthesis of oligonucleotides containing alkyne modification in the middle of the chain.
  • Alkyne-PEG4-phosphoramidite
    Alkyne phosphoramidite for conjugation of oligonucleotides with biomolecules.
  • endo-BCN CE-Phosphoramidite
    BCN-containing phosphoramidite for the synthesis of oligonucleotides and their labeling using copper-free click reactions.

Phosphorylation amidites and supports

Group tags Oligonucleotide synthesis, Phosphoramidites, CPG modifier solid supports

Amino amidites and supports

Group tags Oligonucleotide synthesis, Amines, Phosphoramidites, CPG modifier solid supports

Biotinylation amidites and supports

Group tags Biotinylation, Phosphoramidites, CPG modifier solid supports

Spacer phosphoramidites

Group tags Oligonucleotide synthesis, Phosphoramidites

Polyaromatic phosphoramidites

Group tags Oligonucleotide synthesis, Phosphoramidites, Pyrene

Modified nucleobase amidite

Group tags Oligonucleotide synthesis, Phosphoramidites

Sulfurization reagents

Group tags Oligonucleotide synthesis
  • DDTT Sulfurizing Reagent
    DDTT Sulfurizing Reagent for the fast and efficient production of phosphorothioate oligonucleotides (PTOs).
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