• Products
  • Oligonucleotide synthesis reagents

Oligonucleotide synthesis reagents

Oligonucleotide synthesis reagents / product groups & items in this category
Reagents for oligonucleotide synthesis.

FAM amidites and supports

Fluorescein phosphoramidites and supports used for 3'-, internal, and 5'-modification of oligonucleotides.
Group tags FAM (Fluorescein), Phosphoramidites, Oligonucleotide synthesis, CPG modifier solid supports
    • FAM phosphoramidite, 6-isomer
      FAM (fluorescein) phosphoramidite 6-isomer, is a widely used reagent in nucleic acid chemistry for labeling oligonucleotides. It is derived from the single pure isomer of 6-carboxyfluorescein and separated from amidite linkage via C6 aminohexanol spacer.
    • FAM CPG 500, 6-isomer
      Controlled pore glass for the synthesis of modified oligonucleotides containing 3'-fluorescein (FAM) modification.
    • FAM-dT phosphoramidite
      Phosphoramidite for synthesis of oligonucleotides labeled with fluorescein (FAM) in the middle of sequence.
    • FAM phosphoramidite, 5-isomer
      Single isomer 5-FAM phosphoramidite for the synthesis of modified oligonucleotides.
    • FAM phosphoramidite, 6-isomer (hydroxyprolinol)
      Non-nucleoside phosphoramidite reagent suitable for labeling of oligonucleotides with fluorescein.

Cyanine phosphoramidites

Cyanine dye phosphoramidites for the synthesis of 5'-modified oligos.
Group tags Cyanine5, Phosphoramidites, Cyanine3, Cyanine5.5, Oligonucleotide synthesis

Xanthene amidites and supports (except FAM)

Phosphoramidite reagents for oligonucleotide labeling with xanthene dyes other than fluorescein.
Group tags TET (Tetrachlorofluorescein), Phosphoramidites, JOE, TAMRA (TMR, Tetramethylrhodamine), R6G, VIC, Oligonucleotide synthesis, CPG modifier solid supports, SIMA (Dichloro-diphenyl-fluorescein), HEX (Hexachlorofluorescein)

Quencher phosphoramidites and supports

Solid supports with fluorescence quenchers, and phosphoramidites for the labeling of terminal and internal positions of the oligonucleotide.
Group tags DusQ® 21, DusQ® 1, DusQ® 2, DusQ® 3, Phosphoramidites, Oligonucleotide synthesis, CPG modifier solid supports
    • DusQ® 1 phosphoramidite
      A black quencher dye phosphoramidite for the synthesis of oligonucleotide probes labeled with DusQ® 1 quenchers at 5′-terminal. Useful for HEX, JOE, ROX, Cyanine3.
    • DusQ® 2 phosphoramidite
      DusQ® 2 phosphoramidite for the synthesis of oligonucleotides labeled with DusQ® 2 quencher at 3'-end, 5'-end and internal position. The phosphoramidite has DMT protection and can be used for cartridge purification.
    • DusQ® 1 dT phosphoramidite
      A phosphoramidite used for DusQ® 1 dT labelling of oligonucleotides.
    • DusQ® 2 dT phosphoramidite
      A phosphoramidite used for DusQ® 2 dT labelling of oligonucleotides.
    • DusQ® 1 CPG 500
      Controlled pore glass (CPG) 500 solid support for synthesizing oligonucleotides with 3'-terminal DusQ® 1 quencher. Compatible with standard deblocking conditions.
    • DusQ® 2 CPG 500
      Controlled pore glass (CPG) 500 modified support for the synthesis of oligonucleotides with DusQ® 2 quencher at the 3′ end. Compatible with standard deblocking conditions.
    • DusQ® 1 CPG 1000
      Controlled pore glass (CPG) 1000 solid support for synthesis of oligonucleotides with 3'-terminal DusQ® 1 quencher. Compatible with standard deblocking conditions.
    • DusQ® 1 amidite, 5'-terminal
      Terminal phosphoramidite for labeling oligonucleotides at the 5' end with DusQ® 1 quencher.
    • DusQ® 2 CPG 1000
      Controlled pore glass (CPG) 1000 modified support for the synthesis of oligonucleotides with DusQ® 2 quencher at the 3′ end. Compatible with standard deblocking conditions.
    • DusQ® 3 CPG 500
      DusQ® 3 is a dark quencher for far red and near infrared dyes like Cyanine5.5. This is a controlled pore glass solid support for the synthesis of oligonucleotides with the quencher attached to 3′-terminus.
    • DusQ® 21 CPG 500
      DusQ® 21 is a quencher for dyes in red part of the spectrum, including Cyanine5 and Cyanine5.5.

Universal solid supports

Non-nucleosidic controlled pore glass (CPG) support with universal linkers for the solid phase oligonucleotide automated synthesis of the sequence with any nucleoside at 3'-terminus.
Group tags Oligonucleotide synthesis, CPG modifier solid supports
    • Universal CPG type I, 500A
      This universal support is intended for the automated synthesis of all types of oligonucleotides. Pore size of 500 Å is recommended for the synthesis of oligonucleotides up to 50 bases in length.
    • Universal CPG type II, 1000A
      This universal support is intended for automated synthesis of oligonucleotides to accelerate the dephosphorylation process during deblocking. Pore size of 1000 Å is recommended for the synthesis of oligonucleotides up to 120 bases.
    • Universal CPG type II, 500A
      This universal support is intended for automated synthesis of oligonucleotides for short-term dephosphorylation process during deblocking. Pore size of 500 Å is recommended for the synthesis of oligonucleotides up to 50 bases.
    • MGB CPG 1000
      MGB CPG 1000 for the synthesis of oligonucleotides bearing dihydropyrroloindole tripeptide for binding to the DNA minor groove.

Click chemistry amidites and supports

Phosphoramidites and solid supports for the synthesis of oligonucleotides with azide and alkyne groups capable of downstream Click chemistry modification.
Group tags Cycloalkenes, Copper-free click chemistry, Cycloalkynes, Phosphoramidites, Azides, Alkynes, Oligonucleotide synthesis, CPG modifier solid supports, Click chemistry
    • Alkyne phosphoramidite, 5'-terminal
      Alkyne phosphoramidite for the synthesis of oligonucleotides ready for click chemistry.
    • Alkyne amidite, hydroxyprolinol
      Acetylenic amidite for the incorporation of acetylene groups into oligos.
    • Alkyne CPG modifier 500
      Solid support for the synthesis of 3'-modified oligonucleotides with alkyne group for Click Chemistry.
    • Alkyne CPG 1000A
      Controlled pore glass solid support for DNA/RNA synthesis with alkyne modification (pore size 1000 Å) for synthesizing long-modified oligonucleotides with 3'-alkyne modification.
    • Alkyne dT phosphoramidite
      Phosphoramidite modifier for synthesizing oligonucleotides containing alkyne modification in the middle of the chain.
    • Alkyne-PEG4-phosphoramidite
      Alkyne phosphoramidite for conjugation of oligonucleotides with biomolecules.
    • endo-BCN CE-phosphoramidite
      BCN-containing phosphoramidite for the synthesis of oligonucleotides and their labeling using copper-free click reactions.
    • TCO phosphoramidite C6
      Trans-cyclooctene (TCO) amidite is used to introduce a TCO moiety into substrates containing primary or secondary hydroxyl group
    • 3'-Azido-modifier CPG 1000A
      Controlled pore glass solid support for DNA/RNA synthesis with azide modification (pore size 1000 Å) for the synthesis of long modified oligonucleotides with 3'-azide modification.
    • DBCO-TEG-phosphoramidite
      DBCO-TEG phosphoramidite is a specialized reagent used in the synthesis of oligonucleotides, for applications involving copper-free click chemistry. This phosphoramidite features a dibenzocyclooctyne (DBCO) moiety linked to a triethylene glycol (TEG) spacer, which enhances its solubility and reactivity in various chemical environments.
    • exo-BCN CE-phosphoramidite
      BCN-containing phosphoramidite for the synthesis of oligonucleotides and their labeling using copper-free click reactions.
    • C8-Alkyne-dT-CE-phosphoramidite
      C8-Alkyne-dT-CE-phosphoramidite is a specialized reagent used in the synthesis of oligonucleotides that incorporates a single dT alkyne group. This compound is particularly valuable for applications involving click chemistry, allowing for efficient conjugation reactions.

Phosphorylation amidites and supports

Reagents and solid supports for the solid phase synthesis of 3'- and 5’-phosphorylated oligonucleotides.
Group tags Phosphoramidites, Oligonucleotide synthesis, CPG modifier solid supports

Amino amidites and supports

Reagents for the synthesis of amino modified oligonucleotides, which can be further modified or immobilized on certain solid supports.
Group tags Phosphoramidites, Oligonucleotide synthesis, CPG modifier solid supports

Biotinylation amidites and supports

Phosphoramidites and solid supports for the incorporation of biotin moiety into oligonucleotides.
Group tags Biotinylation, Phosphoramidites, CPG modifier solid supports

Spacer phosphoramidites

Spacer modifiers to insert linkers and spacer arms into oligonucleotides, and to prepare branched oligonucleotides.
Group tags Phosphoramidites, Oligonucleotide synthesis
    • Long trebler phosphoramidite
      Long trebler phosphoramidite is a branching reagent for DNA synthesis, allowing to prepare branched oligonucleotides, and dendrimers.
    • Hexaethylene glycol phosphoramidite
      Spacer phosphoramidite 18 (hexaethylene glycol amidite) provides a long hydrophilic linker for oligo synthesis.
    • Abasic phosphoramidite
      Abasic phosphoramidite for DNA synthesis and DNA damage and repair study.
    • C6 Spacer phosphoramidite
      Spacer 6 phosphoramidite, commonly referred to as C6 spacer amidite, is a specialized reagent used in the synthesis of oligonucleotides. This compound incorporates a 6-carbon hydrophobic spacer into oligonucleotide sequences, either internally or at the 5' end.

Polyaromatic phosphoramidites

Phosphoramidites with polycyclic aromatic hydrocarbons (PAHs) moieties for the introduction of polyaromatic residues in solid-phase synthesised oligonucleotides.
Group tags Phosphoramidites, Pyrene, Oligonucleotide synthesis

Modified nucleobase amidites

Non-standard nucleobase phosphoramidites suitable for solid phase synthesis of modified oligonucleotides.
Group tags Phosphoramidites, Oligonucleotide synthesis

Sulfurization reagents

Reagents for the synthesis of phosphothioate oligomers via amidite chemistry.
Group tags Oligonucleotide synthesis
    • DDTT Sulfurizing Reagent
      DDTT Sulfurizing Reagent for the fast and efficient production of phosphorothioate oligonucleotides (PTOs).
Short link - lumiprobe.com/sh/c/2
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.