DMS(O)MT aminolink C6
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 23260 | 250 mg | $90.00 | in stock | |
| 43260 | 1 g | $260.00 | in stock | |
| 63260 | 5 g |
$950.00
|
in stock | |
| 83260 | 10 g |
$1890.00
|
21 days | |
| 93260 | 25 g |
please inquire
|
21 days |
Aminolink phosphoramidite for oligonucleotide synthesis. DMS(O)MT is a special protective group similar to traditional MMT, but designed as an improved alternative to it. DMS(O)MT aminolink is fully compatible with standard coupling, deblock, and purification protocols. However, DMS(O)MT group is much better suited for DMT-on and cartridge purification of amino-oligonucleotides because of higher stability, and better oligonucleotide recovery. Oligonucleotides containing DMS(O)MT are more stable in solution than MMT analogs.
In case of cartridge purification, DMS(O)MT protection allows for 2-3 fold increase of oligonucleotide yield, making this reagent a unique solution for high-throughput manufacturing of amino-oligonucleotides.
Customers also purchased with this product
TFA-Amino modifier CPG 500
TFA-amino modifier CPG for oligo synthesis. 500 Å, high load controlled pore glass.TFA-aminolinker C6 phosphoramidite
Trifluoroacetyl protected aminolink C6 phosphoramidite for the synthesis of amino-modified oligonucleotides.ROX azide, 5- isomer
ROX (aka rhodamine X or rhodamine 101) azide for biomolecule labeling through Click Chemistry.General properties
| Appearance: | yellowish viscous oil |
| Molecular weight: | 681.86 |
| Molecular formula: | C37H52N3O5PS |
| Solubility: | soluble in acetonitrile, dichloromethane |
| Quality control: | NMR 1H, 31P, HPLC (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. |
| MSDS: | Download |
| Product specifications |
Oligo synthesis details
| Coupling conditions: | standard coupling, identical to normal nucleobases |
| Cleavage conditions: | ammonia, 2 h at room temperature; if an oligonucleotide with trityl group needs to be evaporated, add small amount of Tris base before it, or trityl group can be lost. |
| Deprotection conditions: | identical to protected nucleobases. Trityl group can be removed by acidic cleavage in either 80% acetic acid, or on C18 cartridge during purification using 2% to 4% trifluoroacetic acid. |
Product citations
- Aparin, I.O.; Farzan, V.M.; Veselova, O.A.; Chistov, A.A.; Podkolzin, A.T.; Ustinov, A.V.; Shipulin, G.A.; Formanovsky, A.A.; Korshun, V.A.; Zatsepin, T.S. 1-Phenylethynylpyrene (PEPy) as a novel blue-emitting dye for qPCR assay. Analyst, 2016, 141, 1331–1338. doi: 10.1039/c5an01767j
The count of items is incorrect.
Your cart is empty
$ 
