Cyanine7.5 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 16020 | 1 mg | $110.00 | in stock | |
| 26020 | 5 mg | $210.00 | in stock | |
| 46020 | 25 mg |
$410.00
|
in stock | |
| 56020 | 50 mg |
$695.00
|
in stock | |
| 66020 | 100 mg |
$1190.00
|
in stock |
Cyanine7.5 is a NIR dye with very long-wave emission. This product is amine-reactive derivative of this fluorophore.
Near infrared radiation readily penetrates tissues and can be used for imaging applications in vivo.
This product can be used for the labeling of various biomolecules containing amine groups, such as proteins and peptides, to track their distribution in organism in vivo by NIR imaging.
Increased rigidity of central polymethyne moiety allows to increase quantum yield by 20% compared to parent structure of Cy7.5® NHS.
Cy7.5 absorbance and emission spectra
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Cyanine5.5 alkyne
Cyanine5.5 alkyne is a NIR (near infrared) dye azide for both copper-catalyzed, and copper-free Click Chemistry.BDP 630/650 X NHS ester
BDP 630/650 is a borondipyrromethene fluorophore tuned to Cyanine5 excitation and emission channels. The dye is bright and highly photostable. It is useful for fluorescence polarization assays This is an amine-reactive NHS ester derivative.BDP 630/650 carboxylic acid
BDP 630/650 is a bright fluorophore for far red part of the spectrum. This dye is perfect for microscopy and fluorescence polarization assays. This is a carboxylic acid that can be activated for the coupling, or used as a control.
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General properties
| Appearance: | green powder |
| Mass spec M+ increment: | 630.4 |
| Molecular weight: | 833.76 |
| CAS number: | 1469541-54-5 (without anion), 1469278-04-3 (chloride) |
| Molecular formula: | C49H52N3BF4O4 |
| IUPAC name: | 1H-Benz[e]indolium, 2-[2-[3-[2-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl- |
| Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation maximum, nm: | 788 |
| ε, L⋅mol−1⋅cm−1: | 223000 |
| Emission maximum, nm: | 808 |
Product citations
- Mo, Y.; Du, H.; Chen, B.; Liu, D.; Yin, Q.; Yan, Y.; Wang, Z.; Wan, F.; Qi, T.; Wang, Y.; Zhang, Q.; Wang, Y. Quick-Responsive Polymer-Based Thermo-Sensitive Liposomes for Controlled Doxorubicin Release and Chemotherapy. ACS Biomaterials Science & Engineering, 2019, 5(5), 2316–2329. doi: 10.1021/acsbiomaterials.9b00343
- He, Z.; Hu, Y.; Gui, Z.; Zhou, Y.; Nie, T.; Zhu, J.; Liu, Z.; Chen, K.; Liu, L.; Leong, K.W.; Cao, P.; Chen, Y.; Mao, H.-Q. Sustained release of exendin-4 from tannic acid/Fe (III) nanoparticles prolongs blood glycemic control in a mouse model of type II diabetes. Journal of Controlled Release, 2019, 301, 119–128. doi: 10.1016/j.jconrel.2019.03.014
- Näkki, S.; Wang, J.T.-W.; Wu, J.; Fan, L.; Rantanen, J.; Nissinen, T.; Kettunen, M.I.; Backholm, M.; Ras, R.H.A.; Al-Jamal, K.T.; Lehto, V.-P.; Xu, W. Designed inorganic porous nanovector with controlled release and MRI features for safe administration of doxorubicin. International Journal of Pharmaceutics, 2019, 554, 327–336. doi: 10.1016/j.ijpharm.2018.10.074
- Xu, H.; Bandari, R.; Lee, L.E.; Li, R.; Yu, P.; Smith, C.J.; Ma, L. Design, Synthesis, and In Vitro and In Vivo Evaluation of High Affinity and Specificity Near-Infrared Fluorescent Bombesin Antagonists for Tumor Imaging. Journal of Medicinal Chemistry, 2018, 61(17), 7657–7670. doi: 10.1021/acs.jmedchem.8b00614
Cy® is a trademark of GE Healthcare.
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