Cyanine7.5 NHS ester
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
16020 | 1 mg | $125 | in stock | |
26020 | 5 mg | $260 | in stock | |
46020 | 25 mg | $510 | in stock | |
56020 | 50 mg | $895 | in stock | |
66020 | 100 mg | $1490 | in stock |
Cyanine7.5 is a NIR dye with very long-wave emission. This product is amine-reactive derivative of this fluorophore.
Near infrared radiation readily penetrates tissues and can be used for imaging applications in vivo.
This product can be used for the labeling of various biomolecules containing amine groups, such as proteins and peptides, to track their distribution in organism in vivo by NIR imaging.
Increased rigidity of central polymethyne moiety allows to increase quantum yield by 20% compared to parent structure of Cy7.5® NHS.
Cy7.5 absorbance and emission spectra
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sulfo-Cyanine7.5 dicarboxylic acid
sulfo-Cyanine7.5 dicarboxylic acid is a bifunctional cyanine dye with two carboxylic acid (COOH) groups. The molecule can be used to construct cross conjugates containing a near-infrared emitting fluorophore.Cyanine3 NHS ester
Amine-reactive Cyanine3 dye NHS ester for the labeling of amino-groups.BDP FL carboxylic acid
Borondipyrromethene dye for fluorescein (FAM) channel, free unactivated carboxylic acid useful as a negative control, and for the calibration.
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General properties
Appearance: | green powder |
Mass spec M+ increment: | 630.4 |
Molecular weight: | 833.76 |
CAS number: | 2708152-94-5 |
Molecular formula: | C49H52N3BF4O4 |
IUPAC name: | 1H-Benz[e]indolium, 2-[2-[3-[2-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl- |
Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 788 |
ε, L⋅mol−1⋅cm−1: | 223000 |
Emission maximum, nm: | 808 |
Fluorescence quantum yield: | 0.10 |
Product citations
- Chang, C.; Liu, H.; Li, X.; Song, D.; Liu, Y.; Lu, C.; Zhen, Y.; Chen, Y.; Xu, J.; Li, W.; Jia, X.; Chen, Z.; Chen, R. Combined ROS Responsive Polydopamine-Coated Berberine Nanoparticles Effective Against Ulcerative Colitis in Mouse Model. International Journal of Nanomedicine, 2024, 19, 1205-1224. doi: 10.2147/ijn.s442761
- Tang, M.; Chen, B.; Xia, H.; Pan, M.; Zhao, R.; Zhou, J.; Yin, Q.; Wan, F.; Yan, Y.; Fu, C.; Zhong, L.; Zhang, Q.; Wang, Y. pH-gated nanoparticles selectively regulate lysosomal function of tumour-associated macrophages for cancer immunotherapy. Nature Communications, 2023, 14, 5888. doi: 10.1038/s41467-023-41592-0
- Sreekanth, K.V.; Perumal, J.; Dinish, U.S.; Prabhathan, P.; Liu, Y.; Singh, R.; Olivo, M.; Teng, J. Tunable Tamm plasmon cavity as a scalable biosensing platform for surface enhanced resonance Raman spectroscopy. Nature Communications, 2023, 14, 7085. doi: 10.1038/s41467-023-42854-7
- Nie, Q.; Li, C.; Wang, Y.; Hu, Y.; Pu, W.; Zhang, Q.; Cai, J.; Lin, Y.; Li, G.; Wang, C.; Li, L.; Dou, Y.; Zhang, J. Pathologically Triggered in Situ Aggregation of Nanoparticles for Inflammation-Targeting Amplification and Therapeutic Potentiation. Acta Pharmaceutica Sinica B, 2023, 13(1), 390–409. doi: 10.1016/j.apsb.2022.07.013
Cy® is a trademark of GE Healthcare.
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