Cyanine5.5 DBCO

Cat. # Quantity Price Lead time
A70F0 1 mg $110.00 in stock
B70F0 5 mg $210.00 in stock
C70F0 10 mg $310.00 in stock
D70F0 25 mg $410.00 in stock
E70F0 50 mg $695.00 in stock
F70F0 100 mg $1190.00 in stock

Strain promoted alkyne azide cycloaddition (spAAc) between strained cycloalkynes and azides is a useful bioconjugation method that eliminates the need for copper catalyst necessary for classical CuAAc Click chemistry.

Cyanine5.5 DBCO is a cyclooctyne product containing Cyanine5.5 fluorescent dye. This fluorophore is used in bioimaging, biodistribution studies, and microscopy.

Cyanine5.5 DBCO can be used to conjugate the fluorophore with various azides.

Absorption and emission spectra of Cyanine5.5

Absorption and emission spectra of Cyanine5.5

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Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Cyanine5.5 carboxylic acid

Cy5.5 unactivated free acid cyanine dye.

Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

General properties

Appearance: dark colored solid
Mass spec M+ increment: 882.5
Molecular weight: 1029.14
Molecular formula: C61H63N4F6O2P
Solubility: good in DMF, DMSO, chlorinated organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Fornasier, M.; Porcheddu, A.; Casu, A.; Raghavan, S.R.; Jönsson, P.; Schillén, K.; Murgia, S. Surface-modified nanoerythrosomes for potential optical imaging diagnostics. Journal of Colloid and Interface Science, 2021, 582, 246–253. doi: 10.1016/j.jcis.2020.08.032
  2. Lim, Y.G.; Kim, H.J.; Kim, J.W.; Park, K. Calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging. Journal of Industrial and Engineering Chemistry, 2020, 89, 442–447. doi: 10.1016/j.jiec.2020.06.018
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