Sulfo-Cyanine5.5 NHS ester

Cat. # Quantity Price Lead time
17320 1 mg $110.00 in stock
27320 5 mg $290.00 in stock
47320 25 mg $690.00 in stock
57320 50 mg $1190.00 in stock
67320 100 mg $1850.00 in stock

Sulfo-Cyanine5.5 NHS ester is an amine reactive activated ester of sulfonated far red Cyanine5.5 fluorophore, an analog of Cy5.5®. This is a reagent of choice for the labeling of antibodies, sensitive proteins, and others which require reactions in purely aqueous environment, or without any significant additions of organic co-solvents.

The dye is well suitable for non-invasive in vivo NIR imaging, and for the applications requiring low fluorescent background.

Absorption and emission spectra of sulfo-Cyanine5.5 fluorophore

Absorption and emission spectra of sulfo-Cyanine5.5 fluorophore

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General properties

Appearance: dark blue solid
Mass spec M+ increment: 884.15
Molecular weight: 1114.37
Molecular formula: C44H42N3K3O16S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 675
ε, L⋅mol−1⋅cm−1: 235000
Emission maximum, nm: 694
CF260: 0.09
CF280: 0.11

Product citations

  1. Khatri, S.; Hansen, J.; Mendes, A.C.; Chronakis, I.S.; Hung, S.-C.; Mellins, E.D.; Astakhova, K. Citrullinated Peptide Epitope Targets Therapeutic Nanoparticles to Human Neutrophils. Bioconjugate Chemistry, 2019, 30(10), 2584–2593. doi: 10.1021/acs.bioconjchem.9b00518
  2. Wang, Y.; Li, K.; Han, S.; Tian, Y.-H.; Hu, P.-C.; Xu, X.-L.; He, Y.-Q.; Pan, W.-T.; Gao, Y.; Zhang, Z.; Zhang, J.-W.; Wei, L. Chlorotoxin targets ERα/VASP signaling pathway to combat breast cancer. Cancer Medicine, 2019, 8(4), 1679–1693. doi: 10.1002/cam4.2019
  3. Ha, S.-W.; Hwang, K.; Jin, J.; Cho, A.-S.; Kim, T.Y.; Hwang, S.I.; Lee, H.J.; Kim, C.-Y. Ultrasound-sensitizing nanoparticle complex for overcoming the blood-brain barrier: an effective drug delivery system. International Journal of Nanomedicine, 2019, 14, 3743–3752. doi: 10.2147/ijn.s193258
  4. Liu, R.; Li, Z.; Marvin, J.S.; Kleinfeld, D. Direct wavefront sensing enables functional imaging of infragranular axons and spines. Nature Methods, 2019, 16, 615–618. doi: 10.1038/s41592-019-0434-7
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