Sulfo-Cyanine5.5 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 17320 | 1 mg | $110.00 | in stock | |
| 27320 | 5 mg | $290.00 | in stock | |
| 47320 | 25 mg |
$690.00
|
in stock | |
| 57320 | 50 mg |
$1190.00
|
in stock | |
| 67320 | 100 mg |
$1850.00
|
in stock |
Sulfo-Cyanine5.5 NHS ester is an amine reactive activated ester of sulfonated far red Cyanine5.5 fluorophore, an analog of Cy5.5®. This is a reagent of choice for the labeling of antibodies, sensitive proteins, and others which require reactions in purely aqueous environment, or without any significant additions of organic co-solvents.
The dye is well suitable for non-invasive in vivo NIR imaging, and for the applications requiring low fluorescent background.
Absorption and emission spectra of sulfo-Cyanine5.5 fluorophore
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Sulfo-Cyanine3 alkyne
A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.Coumarin 343 X NHS ester
Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.Cyanine5 amine
Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.
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General properties
| Appearance: | dark blue solid |
| Mass spec M+ increment: | 884.15 |
| Molecular weight: | 1114.37 |
| Molecular formula: | C44H42N3K3O16S4 |
| Solubility: | good in water, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation maximum, nm: | 675 |
| ε, L⋅mol−1⋅cm−1: | 195000 |
| Emission maximum, nm: | 694 |
| CF260: | 0.09 |
| CF280: | 0.11 |
Product citations
- Kwon, Y.-D.; Oh, J.-M.; La, M.T.; Chung, H.-J.; Lee, S.J.; Chun, S.; Lee, S.-H.; Jeong, B.-H.; Kim, H.-K. Synthesis and Evaluation of Multifunctional Fluorescent Inhibitors with Synergistic Interaction of PSMA and Hypoxia for Prostate Cancer. Bioconjugate Chemistry, 2019, 30(1), 90–100. doi: 10.1021/acs.bioconjchem.8b00767
- Liu, Y.; Wang, Z.; Li, X.; Ma, X.; Wang, S.; Kang, F.; Yang, W.; Ma, W.; Wang, J. Near-infrared Fluorescent Peptides with High Tumor Selectivity: Novel Probes for Image-Guided Surgical Resection of Orthotopic Glioma. Molecular Pharmaceutics, 2019, 16(1), 108–117. doi: 10.1021/acs.molpharmaceut.8b00888
- Jasinski, D.L.; Yin, H.; Li, Z.; Guo, P. The Hydrophobic Effect from Conjugated Chemicals or Drugs on in Vivo Biodistribution of RNA Nanoparticles. Human Gene Therapy, 2018, 29(1), 77–86. doi: 10.1089/hum.2017.054
- Park, S.; Shevlin, E.; Vedvyas, Y.; Zaman, M.; Park, S.; Hsu, Y.-M.S.; Min, I.M.; Jin, M.M. Micromolar affinity CAR T cells to ICAM-1 achieves rapid tumor elimination while avoiding systemic toxicity. Scientific Reports, 2017, 7, 14366. doi: 10.1038/s41598-017-14749-3
Cy® is a trademark of GE Healthcare.
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