Alkynes in Reactive groups

Terminal alkynes react with azides in a copper-catalyzed process called copper-catalyzed alkyne azide cycloaddition (CuAAC). The reaction is a useful method for the conjugation and fluorescent labeling of biomolecules.

Click chemistry (CuAAc) reaction scheme

Lumiprobe offers a range of terminal alkyne derivatives, including fluorescent dye alkynes, and linkers with alkyne group.

1-Ethynyl pyrene

Pyrene is a polyaromatic hydrocarbon containing four fused rings. This reagent contains a terminal alkyne group for click chemistry and other reactions, such as Sonogashira coupling.
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Cat. # Quantity Price Lead time
515B0 50 mg $30.00 in stock
615B0 100 mg $50.00 in stock

3-Ethynyl perylene

Alkyne derivative of ultra-bright and photostable perylene fluorophore.
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Cat. # Quantity Price Lead time
555B0 50 mg $50.00 in stock
655B0 100 mg $80.00 in stock

AF 430 alkyne

AF 430 is a dye emitting in the green-yellow range. A dye is useful for flow cytometry.
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Cat. # Quantity Price Lead time
A08B0 1 mg $110.00 in stock
B08B0 5 mg $290.00 in stock
C08B0 10 mg $470.00 in stock
D08B0 25 mg $690.00 in stock
E08B0 50 mg $1270.00 in stock
F08B0 100 mg $1990.00 in stock

AF 488 alkyne, 5-isomer

Alkyne derivative of AF 488 dye for copper-catalyzed cycloaddition to azides.
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Cat. # Quantity Price Lead time
A18B0 1 mg $110.00 in stock
B18B0 5 mg $290.00 in stock
D18B0 25 mg $690.00 in stock
E18B0 50 mg $1270.00 in stock
F18B0 100 mg $1990.00 in stock

AF 568 alkyne, 5-isomer

AF 568 derivative designed for fluorescence microscopy and flow cytometry.
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Cat. # Quantity Price Lead time
A48B0 1 mg $110.00 in stock
B48B0 5 mg $290.00 in stock
C48B0 10 mg $470.00 in stock
D48B0 25 mg $690.00 in stock
E48B0 50 mg $1270.00 in stock
F48B0 100 mg $1990.00 in stock

Alkyne amidite, hydroxyprolinol

Acetylenic amidite for the incorporation of acetylene groups into oligos.
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Cat. # Quantity Price Lead time
21360 250 mg $110.00 in stock
41360 1 g $390.00 in stock

Alkyne CPG modifier 500

Solid support for the synthesis of 3'-modified oligonucleotides with alkyne group for Click Chemistry.
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Cat. # Quantity Price Lead time
12860 100 mg $60.00 in stock
22860 250 mg $120.00 in stock
32860 500 mg $230.00 in stock
42860 1 g $380.00 in stock
52860 5 g $1450.00 in stock

Alkyne dT phosphoramidite

Phosphoramidite modifier for the synthesis of oligonucleotides containing alkyne modification in the middle of the chain.
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Cat. # Quantity Price Lead time
1897-100mg 100 mg $330.00 in stock
1897-1g 1 g $2590.00 in stock
1897-5g 5 g $9900.00 in stock

Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.
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Cat. # Quantity Price Lead time
41770 25 mg $95.00 in stock
51770 50 mg $195.00 in stock
61770 100 mg $290.00 in stock

Alkyne maleimide

Maleimide reagent for the attachment of alkyne functional group to proteins, peptides, and other molecules bearing SH (thiol) groups, including cysteine residues.
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Cat. # Quantity Price Lead time
41780 25 mg $95.00 in stock
51780 50 mg $175.00 in stock
61780 100 mg $200.00 in stock

Alkyne Phosphoramidite, 5'-terminal

Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.
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Cat. # Quantity Price Lead time
22260 250 mg $110.00 in stock
32260 500 mg $190.00 in stock
42260 1 g $310.00 in stock
62260 5 g $1290.00 in stock
82260 10 g please inquire in stock

Alkyne-PEG2-amine

Diethyleneglycol (PEG2) based bifunctional linker containing amine and alkyne functional groups.
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Cat. # Quantity Price Lead time
2065-1g 1 g $120.00 in stock
2065-5g 5 g $350.00 in stock
2065-25g 25 g please inquire in stock

Alkyne-PEG2-carboxylic acid

Bifunctional diethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
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Cat. # Quantity Price Lead time
2155-1g 1 g $380.00 7 days

Alkyne-PEG2-iodide

Bifunctional reactive crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling, and reactive alkyl iodide group.
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Cat. # Quantity Price Lead time
2136-1g 1 g $450.00 in stock

Alkyne-PEG2-NHS ester

Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on diethyleneglycol (PEG2).
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Cat. # Quantity Price Lead time
2219-1g 1 g $490.00 in stock
2219-5g 5 g $980.00 21 days

Alkyne-PEG3-amine

Alkyne-PEG3-amine is a medium-length heterobifunctional linker for conjugation.
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Cat. # Quantity Price Lead time
425-1g 1 g $195.00 in stock
425-5g 5 g $580.00 in stock

Alkyne-PEG3-carboxylic acid

Bifunctional triethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
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Cat. # Quantity Price Lead time
1743-1g 1 g $490.00 in stock
1743-5g 5 g $980.00 in stock
1743-25g 25 g please inquire in stock

Alkyne-PEG3-Iodide

PEG3 with alkyne and iodide functional groups, a reactive and hydrophilic linker for alkylation and Click chemistry.
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Cat. # Quantity Price Lead time
2193-1g 1 g $490.00 in stock
2193-5g 5 g $1150.00 in stock
2193-25g 25 g please inquire in stock

Alkyne-PEG3-maleimide

Bifunctional spacer with alkyne and maleimide groups.
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Cat. # Quantity Price Lead time
2344-100mg 100 mg $140.00 in stock
2344-1g 1 g $530.00 in stock

Alkyne-PEG3-NHS ester

Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on triethyleneglycol (PEG3).
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Cat. # Quantity Price Lead time
2298-1g 1 g $490.00 in stock
2298-5g 5 g $980.00 21 days
2298-25g 25 g please inquire 21 days

Alkyne-PEG3-OH

Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.
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Cat. # Quantity Price Lead time
418-1g 1 g $95.00 in stock
418-5g 5 g $280.00 in stock
418-25g 25 g please inquire in stock

Alkyne-PEG4-amine

A bifunctional linker molecule containing both terminal alkyne moiety for click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.
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Cat. # Quantity Price Lead time
2025-100mg 100 mg $95.00 in stock
2025-1g 1 g $390.00 in stock

Alkyne-PEG4-carboxylic acid

Bifunctional tetraethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
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Cat. # Quantity Price Lead time
2187-1g 1 g $380.00 12 days

Alkyne-PEG4-iodide

Bifunctional reactive PEG4-based crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling and reactive alkyl iodide group.
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Cat. # Quantity Price Lead time
2188-1g 1 g $450.00 12 days

Alkyne-PEG4-maleimide

Water soluble, heterobifunctional hydrophilic linker with a length of 14 Å, containing maleimide for thiol labeling, and alkyne for click chemistry. An ideal reagent to attach an alkyne moiety to a protein.
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Cat. # Quantity Price Lead time
2002-100mg 100 mg $150.00 in stock
2002-1g 1 g $590.00 in stock