Alkynes in Reactive groups

Terminal alkynes react with azides in a copper catalyzed process called copper catalyzed alkyne azide cycloaddition (CuAAc). The reaction is a useful method for the conjugation and fluorescent labeling of biomolecules.

Click chemistry (CuAAc) reaction scheme

Lumiprobe offers a range of terminal alkyne derivatives, including fluorescent dye alkynes, and linkers with alkyne group.

1-Ethynyl pyrene

Pyrene is polyaromatic hydrocarbon containing four fused rings. This reagent contains terminal alkyne group for Click Chemistry and other reactions, such as Sonogashira coupling.
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Cat. # Quantity Price Lead time
515B0 50 mg $30.00 in stock
615B0 100 mg $50.00 in stock

3-Ethynyl perylene

Alkyne derivative of ultra-bright and photostable perylene fluorophore.
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Cat. # Quantity Price Lead time
555B0 50 mg $50.00 in stock
655B0 100 mg $80.00 in stock

AF430 alkyne

AF430 is a dye emitting in green-yellow range. A dye is useful for flow cytometry.
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Cat. # Quantity Price Lead time
A08B0 1 mg $110.00 in stock
B08B0 5 mg $290.00 in stock
C08B0 10 mg $470.00 in stock
D08B0 25 mg $690.00 in stock
E08B0 50 mg $1270.00 in stock
F08B0 100 mg $1990.00 in stock

AF568 alkyne, 5-isomer

AF568 derivative designed for fluorescence microscopy and flow cytometry
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Cat. # Quantity Price Lead time
A48B0 1 mg $110.00 in stock
B48B0 5 mg $290.00 in stock
C48B0 10 mg $470.00 in stock
D48B0 25 mg $690.00 in stock
E48B0 50 mg $1270.00 in stock
F48B0 100 mg $1990.00 in stock

Alkyne Amidite, hydroxyprolinol

Acetylenic amidite for the incorporation of acetylene groups into oligos.
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Cat. # Quantity Price Lead time
21360 250 mg $110.00 in stock
41360 1 g $390.00 in stock

Alkyne CPG modifier 500

Solid support for the synthesis of 3'-modified oligonucleotides with alkyne group for Click Chemistry.
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Cat. # Quantity Price Lead time
12860 100 mg $60.00 in stock
22860 250 mg $120.00 in stock
32860 500 mg $230.00 in stock
42860 1 g $380.00 in stock
52860 5 g $1450.00 in stock

Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.
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Cat. # Quantity Price Lead time
41770 25 mg $95.00 in stock
51770 50 mg $195.00 in stock
61770 100 mg $290.00 in stock

Alkyne maleimide

Maleimide reagent for the attachment of alkyne functional group to proteins, peptides, and other molecules bearing SH (thiol) groups, including cysteine residues.
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Cat. # Quantity Price Lead time
41780 25 mg $95.00 in stock
51780 50 mg $195.00 in stock
61780 100 mg $290.00 in stock

Alkyne NHS ester (hexynoic acid NHS ester)

Alkyne NHS ester for the labeling of biomolecules with alkyne group for Copper catalyzed Click chemistry.
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Cat. # Quantity Price Lead time
41720 25 mg $95.00 5 days
51720 50 mg $180.00 in stock
61720 100 mg $290.00 in stock
91720 1 g please inquire in stock

Alkyne Phosphoramidite, 5'-terminal

Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.
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Cat. # Quantity Price Lead time
22260 250 mg $110.00 in stock
32260 500 mg $190.00 in stock
42260 1 g $310.00 in stock
62260 5 g $1290.00 in stock
82260 10 g please inquire in stock

Alkyne-PEG2-amine

Diethyleneglycol (PEG2) based bifunctional linker, containing amine and alkyne functional groups.
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Cat. # Quantity Price Lead time
2065-1g 1 g $120.00 in stock
2065-5g 5 g $350.00 in stock
2065-25g 25 g please inquire in stock

Alkyne-PEG2-iodide

Bifunctional reactive cross linker containing terminal alkyne group for Click chemistry or Sonogashira coupling, and reactive alkyl iodide group.
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Cat. # Quantity Price Lead time
2136-1g 1 g $490.00 in stock

Alkyne-PEG3-amine

Alkyne PEG3 amine is a medium length heterobifunctional linker for the conjugation.
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Cat. # Quantity Price Lead time
425-1g 1 g $195.00 in stock
425-5g 5 g $580.00 in stock

Alkyne-PEG3-COOH

Bifunctional linker with terminal alkyne function, and carboxylic acid moiety, CAS# 1415800-32-6.
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Cat. # Quantity Price Lead time
1743-1g 1 g $490.00 in stock
1743-5g 5 g $980.00 in stock
1743-25g 25 g please inquire in stock

Alkyne-PEG3-Iodide

PEG3 with alkyne and iodide functional groups, a reactive and hydrophilic linker for alkylation and Click chemistry.
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Cat. # Quantity Price Lead time
2193-1g 1 g $490.00 in stock
2193-5g 5 g $1150.00 in stock
2193-25g 25 g please inquire in stock

Alkyne-PEG3-maleimide

Bifunctional spacer with alkyne and maleimide groups.
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Cat. # Quantity Price Lead time
2344-100mg 100 mg $140.00 in stock
2344-1g 1 g $530.00 in stock

Alkyne-PEG3-NHS ester

Bifunctional hyrophilic linker with NHS ester and terminal alkyne functional group based on triethyleneglycol (PEG3).
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Cat. # Quantity Price Lead time
2298-1g 1 g $490.00 in stock
2298-5g 5 g $980.00 21 days
2298-25g 25 g please inquire 21 days

Alkyne-PEG3-OH

Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.
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Cat. # Quantity Price Lead time
418-1g 1 g $95.00 in stock
418-5g 5 g $280.00 in stock
418-25g 25 g please inquire in stock

Alkyne-PEG4-Amine

A bifunctional linker molecule containing both terminal alkyne moiety for Click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.
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Cat. # Quantity Price Lead time
2025-100mg 100 mg $95.00 in stock
2025-1g 1 g $390.00 in stock

Alkyne-PEG4-Maleimide

Water soluble, heterobifunctional hydrophilic linker with a length of 14 Å, containing maleimide for thiol labeling, and alkyne for Click chemistry. An ideal reagent to attach an alkyne moiety to a protein.
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Cat. # Quantity Price Lead time
2002-100mg 100 mg $150.00 in stock
2002-1g 1 g $590.00 in stock

Alkyne-PEG4-phosphoramidite

Alkyne phosphoramidite for conjugation of oligonucleotides with biomolecules.
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Cat. # Quantity Price Lead time
2779-100mg 100 mg $390.00 in stock
2779-250mg 250 mg $680.00 in stock
2779-1g 1 g $1640.00 in stock
2779-5g 5 g please inquire 5 days

BDP 558/568 alkyne

BDP 558/568 is a borondipyrromethene dye for Cyanine3 channel. This is a terminal alkyne derivative.
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Cat. # Quantity Price Lead time
A74B0 1 mg $110.00 in stock
B74B0 5 mg $210.00 in stock
C74B0 10 mg $310.00 in stock
D74B0 25 mg $410.00 in stock
E74B0 50 mg $695.00 in stock
F74B0 100 mg $1190.00 in stock

BDP 581/591 alkyne

BDP 581/591 is a borondipyrromethene fluorophore which is useful for fluorescence polarization assays, microscopy, and two photon experiments. This alkyne is a derivative for copper-catalyzed Click chemistry.
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Cat. # Quantity Price Lead time
A64B0 1 mg $110.00 in stock
B64B0 5 mg $210.00 in stock
C64B0 10 mg $310.00 in stock
D64B0 25 mg $410.00 in stock
E64B0 50 mg $695.00 in stock
F64B0 100 mg $1190.00 in stock

BDP 650/665 alkyne

BDP 650/665 alkyne is a red emitting BODIPY dye derivative carrying a terminal alkyne group for a copper catalyzed conjugation with azides. Absorption and emission spectra of BDP 650/665 are designed to fit Cy5 channel of various instruments.
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Cat. # Quantity Price Lead time
A84B0 1 mg $110.00 in stock
B84B0 5 mg $210.00 in stock
C84B0 10 mg $310.00 in stock
D84B0 25 mg $410.00 in stock
E84B0 50 mg $695.00 in stock
F84B0 100 mg $1190.00 in stock

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.
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Cat. # Quantity Price Lead time
A14B0 1 mg $110.00 in stock
B14B0 5 mg $210.00 in stock
C14B0 10 mg $310.00 in stock
D14B0 25 mg $410.00 in stock
E14B0 50 mg $695.00 in stock
F14B0 100 mg $1190.00 in stock

BDP R6G alkyne

Terminal alkyne derivative of BDP R6G dye for Click chemistry. BDP R6G is a borondipyrromethene dye whose absorption and emission spectra are similar to R6G (rhodamine 6G).
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Cat. # Quantity Price Lead time
A44B0 1 mg $110.00 in stock
B44B0 5 mg $210.00 in stock
C44B0 10 mg $310.00 in stock
D44B0 25 mg $410.00 in stock
E44B0 50 mg $695.00 in stock
F44B0 100 mg $1190.00 in stock

BDP TMR alkyne

Borondipyrromethene dye for TAMRA channel, with alkyne group for copper-catalyzed Click Chemistry.
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Cat. # Quantity Price Lead time
A24B0 1 mg $110.00 in stock
B24B0 5 mg $210.00 in stock
C24B0 10 mg $310.00 in stock
D24B0 25 mg $410.00 in stock
E24B0 50 mg $695.00 in stock
F24B0 100 mg $1190.00 in stock

BDP TR alkyne

BDP TR is a fluorophore for ROX channel. This borondipyrromethene dye is very bright, and resistant to oxidation.
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Cat. # Quantity Price Lead time
A34B0 1 mg $110.00 in stock
B34B0 5 mg $210.00 in stock
C34B0 10 mg $310.00 in stock
D34B0 25 mg $410.00 in stock
E34B0 50 mg $695.00 in stock
F34B0 100 mg $1190.00 in stock

Biotin alkyne

Biotin alkyne is a reactive affinity label which can be attached to biomolecules via Click Chemistry.
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Cat. # Quantity Price Lead time
C37B0 10 mg $90.00 in stock
D37B0 25 mg $160.00 in stock
E37B0 50 mg $270.00 in stock
F37B0 100 mg $420.00 5 days

Cyanine3 alkyne

Cyanine3 alkyne is a fluorescent dye alkyne for Click Chemistry.
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Cat. # Quantity Price Lead time
A10B0 1 mg $110.00 in stock
B10B0 5 mg $210.00 in stock
C10B0 10 mg $310.00 in stock
D10B0 25 mg $410.00 in stock
E10B0 50 mg $695.00 in stock
F10B0 100 mg $1190.00 in stock