Alkyne dT phosphoramidite
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 1897-100mg | 100 mg | $270.00 | in stock | |
| 1897-1g | 1 g |
$1590.00
|
in stock | |
| 1897-5g | 5 g |
$5400.00
|
in stock |
This reagent is designed for the synthesis of oligonucleotides bearing triple bond (alkyne) in the middle of the chain. Alkyne is attached to deoxyuridine fragment, and it does not interfere with the hybridization to the complementary strand. This allows to prepare modified oligonucleotide probes bearing fluorescent dyes, quenchers, and other fragments attached to the middle of the chain, by virtue of copper catalyzed Click chemistry reaction with various azides.
This phosphoramidite is solid, so it is easy to dispense and handle. It is compatible with the standard deblocking conditions.
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TFA-amino modifier CPG for oligo synthesis. 500 Å, high load controlled pore glass.Cyanine5.5 azide
Far red / near infrared fluorescent Cyanine5.5 dye derivative for Click Chemistry.General properties
| Appearance: | off white solid |
| Mass spec M+ increment: | 437.1 |
| Molecular weight: | 877.96 |
| Molecular formula: | C48H56N5O9P |
| MSDS: | Download |
| Product specifications |
Oligo synthesis details
| Diluent: | acetonitrile |
| Coupling conditions: | standard coupling, identical to normal nucleobases |
| Cleavage conditions: | ammonia, 2 h at room temperature |
| Deprotection conditions: | identical to protected nucleobases |
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