Alkyne dT phosphoramidite

Cat. # Quantity Price Lead time
1897-100mg 100 mg $330.00 in stock
1897-1g 1 g $2590.00 in stock
1897-5g 5 g $9900.00 in stock

This reagent is designed for the synthesis of oligonucleotides bearing triple bond (alkyne) in the middle of the chain. Alkyne is attached to deoxyuridine fragment, and it does not interfere with the hybridization to the complementary strand. This allows to prepare modified oligonucleotide probes bearing fluorescent dyes, quenchers, and other fragments attached to the middle of the chain, by virtue of copper catalyzed Click chemistry reaction with various azides.

This phosphoramidite is solid, so it is easy to dispense and handle. It is compatible with the standard deblocking conditions.

Customers also purchased with this product

TFA-aminolinker C6 phosphoramidite

Trifluoroacetyl protected aminolink C6 phosphoramidite for the synthesis of amino-modified oligonucleotides.

TFA-Amino modifier CPG 500

TFA-amino modifier CPG for oligo synthesis. 500 Å, high load controlled pore glass.

Hexaethylene glycol phosphoramidite

Spacer phosphoramidite 18 (hexaethylene glycol amidite) provides a long hydrophilic linker for oligo synthesis.

General properties

Appearance: off white solid
Mass spec M+ increment: 437.1
Molecular weight: 877.96
Molecular formula: C48H56N5O9P
Solubility: good in acetonitrile, DCM
Quality control: NMR 1H, NMR 31P, HPLC-MS
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Oligo synthesis details

Diluent: acetonitrile
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.