SIMA (Dichloro-diphenyl-fluorescein) in Fluorophores

Absorption max 531 nm Emission max 555 nm Fluorophore chart
SIMA or dichloro-diphenyl-fluorescein is a dye with spectral properties similar to HEX, but with a higher quantum yield. SIMA also has improved stability during deprotection under basic conditions

SIMA azide, 6-isomer

Azide of green-yellow emitting dye SIMA for conjugation with oligonucleotides via [3+2]-dipolar cycloaddition.
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Cat. # Quantity Price Lead time
AE230 1 mg
$110
in stock
BE230 5 mg
$180
in stock
CE230 10 mg
$310
in stock
DE230 25 mg
$410
in stock
EE230 50 mg
$695
in stock
FE230 100 mg
$1190
in stock
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SIMA carboxylic acid, 6-isomer

Derivative of SIMA fluorophore with non-activated free carboxylic acid group.
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Cat. # Quantity Price Lead time
2E290 5 mg
$125
21 days
4E290 25 mg
$225
21 days
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SIMA phosphoramidite, 6-isomer

A phosphoramidite for the synthesis of SIMA-labeled oligonucleotides. SIMA is a more stable analog of HEX.
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Cat. # Quantity Price Lead time
DE260
/ Easily soluble lyophilised form in 6 mL septum
250 mg
$202
in stock
EE260
/ Easily soluble lyophilised form in 8 mL septum
500 mg
$340
in stock
FE260
/ Easily soluble lyophilised form in 20 mL septum
1 g
$575
in stock
HE260 10 g
please inquire
in stock
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SIMA phosphoramidite, 6-isomer (hydroxyprolinol)

A phosphoramidite (hydroxyprolinol) for the synthesis of SIMA-labeled oligonucleotides. SIMA is a more stable analog of HEX.
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Cat. # Quantity Price Lead time
13360
/ Easily soluble lyophilised form in 6 mL septum
100 mg
$140 $120
in stock
23360
/ Easily soluble lyophilised form in 6 mL septum
250 mg
$340 $290
in stock
43360
/ Easily soluble lyophilised form in 6 mL septum
1 g
$990 $790
in stock
63360 5 g
$3900 $3390
in stock
83360 10 g
please inquire
21 days
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SIMA-dT phosphoramidite, 6-isomer

Phosphoramidite for synthesis of oligonucleotides labeled with SIMA in the middle of sequence.
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Cat. # Quantity Price Lead time
2950-100mg 100 mg
$180
in stock
2950-250mg 250 mg
$390
in stock
2950-1g 1 g
$1120
in stock
2950-5g 5 g
$4520
in stock
2950-10g 10 g
$8650
in stock
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