Tetrazines in Reactive groups
Tetrazines (1,2,4,5-tetrazine) are a six-membered cyclic system with four nitrogen atoms. Tetrazines react extremely fast with terminal alkenes and trans-cyclooctenes in Inverse electron demand Diels-Alder ligation (IEDDA). IEDDA is the fastest cycloaddition reaction among click reactions known. It possesses exceptional selectivity and kinetics. Tetrazines also react with some strained cycloalkynes. IEDDA ligation is a fast and easy method to perform labeling or bioconjugation.
AF 430 tetrazine
Tetrazine derivative of AF 430 fluorescent dye suitable for in vitro cell labeling.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 108E0 | 1 mg | $125 | in stock | |
| 208E0 | 5 mg | $325 | in stock | |
| 308E0 | 10 mg |
$480
|
in stock | |
| 408E0 | 25 mg |
$950
|
in stock | |
| 508E0 | 50 mg |
$1625
|
in stock | |
| 608E0 | 100 mg |
$2090
|
in stock |
AF 488 tetrazine, 5-isomer
Tetrazine derivative of AF 488 fluorophore for TCO ligation and in vitro cell labeling.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 118E0 | 1 mg | $140 | in stock | |
| 218E0 | 5 mg |
$450
|
in stock | |
| 418E0 | 25 mg |
$1460
|
in stock | |
| 518E0 | 50 mg |
$1890
|
in stock | |
| 618E0 | 100 mg |
$2640
|
in stock |
AF 594 tetrazine, 6-isomer
Tetrazine derivative of AF 594 fluorophore for TCO ligation and in vitro labeling.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 178E0 | 1 mg | $198 | in stock | |
| 278E0 | 5 mg |
$736
|
in stock | |
| 478E0 | 25 mg |
$2396
|
in stock |
Azide-PEG3-tetrazine
A hydrophilic bifunctional linker with azide and tetrazine function groups flanking PEG3 (triethylene glycol) spacer.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 2798-250mg | 250 mg |
$549
|
in stock |
BDP® 558/568 tetrazine
Stable fluorophore that can be conjugated with trans-cyclooctene derivatives of biomolecules for their visualization.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A74E0 | 1 mg | $125 | in stock | |
| B74E0 | 5 mg | $260 | in stock | |
| C74E0 | 10 mg | $325 | in stock | |
| D74E0 | 25 mg |
$510
|
in stock | |
| E74E0 | 50 mg |
$895
|
in stock | |
| F74E0 | 100 mg |
$1490
|
in stock |
BDP® 576/589 tetrazine
Tetrazine derivative of BDP 576/589 hydrophobic dye for conjugation with trans-cyclooctenes and cyclopropenes in the TCO ligation reaction.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 1G4E0 | 1 mg | $110 | in stock | |
| 2G4E0 | 5 mg | $290 | in stock | |
| 3G4E0 | 10 mg |
$450
|
in stock | |
| 4G4E0 | 25 mg |
$690
|
in stock | |
| 5G4E0 | 50 mg |
$1270
|
in stock | |
| 6G4E0 | 100 mg |
$1990
|
in stock |
BDP® 581/591 tetrazine
BDP 581/591 is a borondipyrromethene dye with a tetrazine group for the inverse electron demand Diels-Alder (IEDDA) ligation.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 164E0 | 1 mg | $110 | in stock | |
| 264E0 | 5 mg | $290 | in stock | |
| 464E0 | 25 mg |
$690
|
in stock | |
| 564E0 | 50 mg |
$1270
|
in stock | |
| 664E0 | 100 mg |
$1990
|
in stock |
BDP® 630/650 tetrazine
BDP 630/650 is a borondipyrromethene dye for Cyanine5 channel. This is a tetrazine derivative for the coupling with strained cycloalkenes.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 154E0 | 1 mg | $110 | in stock | |
| 254E0 | 5 mg | $290 | in stock | |
| 454E0 | 25 mg |
$690
|
in stock | |
| 554E0 | 50 mg |
$1270
|
in stock | |
| 654E0 | 100 mg |
$1990
|
in stock |
BDP® FL tetrazine
BDP FL tetrazine (methyltetrazine) is a reactive dye for the inverse electron demand Diels-Alder (IEDDA) reaction with trans-cyclooctenes, cyclopropenes, and other strained cycloolefines. BDP FL is a bright and photostable dye for the 488 nm fluorescein (FAM) channel.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 114E0 | 1 mg | $110 | in stock | |
| 214E0 | 5 mg | $290 | in stock | |
| 414E0 | 25 mg |
$690
|
in stock | |
| 514E0 | 50 mg |
$1270
|
in stock | |
| 614E0 | 100 mg |
$1990
|
in stock |
BDP® R6G tetrazine
BDP R6G tetrazine is a borondipyrromethene dye with absorption and emission wavelengths similar to those of rhodamine 6G. It contains a tetrazine fragment for IEDDA ligation.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 144E0 | 1 mg | $110 | in stock | |
| 244E0 | 5 mg | $290 | in stock | |
| 444E0 | 25 mg |
$690
|
in stock | |
| 544E0 | 50 mg |
$1270
|
in stock | |
| 644E0 | 100 mg |
$1990
|
in stock |
BDP® TMR tetrazine
A fluorophore for the TAMRA channel with a functional group that can form conjugates in click chemistry reactions (IEDDA ligation) .
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 124E0 | 1 mg | $125 | in stock | |
| 224E0 | 5 mg | $260 | in stock | |
| 424E0 | 25 mg |
$510
|
in stock | |
| 524E0 | 50 mg |
$895
|
in stock | |
| 624E0 | 100 mg |
$1490
|
in stock |
BDP® TR tetrazine
BDP TR is a borondipyrromethene fluorophore for the ROX channel. The dye produces bright fluorescent emission. Tetrazines are reactive components for the conjugation with strained cycloalkenes.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 134E0 | 1 mg | $110 | in stock | |
| 234E0 | 5 mg | $290 | in stock | |
| 434E0 | 25 mg |
$690
|
in stock | |
| 534E0 | 50 mg |
$1270
|
in stock | |
| 634E0 | 100 mg |
$1990
|
in stock |
Biotin-PEG4-tetrazine
Biotin tetrazine is a reagent for copper-free click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 3797-25mg | 25 mg | $210 | in stock | |
| 3797-250mg | 250 mg |
$1190
|
in stock |
Cyanine3 tetrazine
Tetrazine derivative of the fluorophore Cyanine3. Tetrazines react extremely quickly with strained alkenes (such as trans-cyclooctenes, cyclopropenes), and some strained alkynes.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 110E0 | 1 mg | $125 | in stock | |
| 210E0 | 5 mg | $260 | in stock | |
| 410E0 | 25 mg |
$510
|
in stock | |
| 510E0 | 50 mg |
$895
|
in stock | |
| 610E0 | 100 mg |
$1490
|
in stock |
Cyanine3B tetrazine
Cyanine3B dye tetrazine derivative for IEDDA conjugation with strained olefins and terminal alkenes.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 193E0 | 1 mg | $348 | in stock | |
| 293E0 | 5 mg |
$737
|
in stock | |
| 493E0 | 25 mg |
$1950
|
in stock |
Cyanine5 tetrazine
Cyanine5 is a universal red emitting dye with a very high extinction coefficient, and good quantum yield. This tetrazine derivative reacts very quickly with trans-cyclooctenes and cyclopropenes with the formation of stable conjugates.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 130E0 | 1 mg | $125 | in stock | |
| 230E0 | 5 mg | $260 | in stock | |
| 430E0 | 25 mg |
$510
|
in stock | |
| 530E0 | 50 mg |
$895
|
in stock | |
| 630E0 | 100 mg |
$1490
|
in stock |
Cyanine5.5 tetrazine
A compound containing Cyanine5.5 fluorophore, a far red emitting dye, and tetrazine fragment for the conjugation with trans-cyclooctenes / cyclopropenes via TCO ligation.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 170E0 | 1 mg | $125 | in stock | |
| 270E0 | 5 mg | $260 | in stock | |
| 470E0 | 25 mg |
$510
|
in stock | |
| 570E0 | 50 mg |
$895
|
in stock | |
| 670E0 | 100 mg |
$1490
|
in stock |
Cyanine7 tetrazine
Near infrared Cyanine7 dye derivative containing tetrazine group for TCO ligation.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 150E0 | 1 mg | $125 | in stock | |
| 250E0 | 5 mg | $325 | in stock | |
| 450E0 | 25 mg |
$510
|
in stock | |
| 550E0 | 50 mg |
$895
|
in stock | |
| 650E0 | 100 mg |
$1490
|
in stock |
Cyanine7.5 tetrazine
Cyanine7.5 tetrazine is a tetrazine derivative for TCO ligation and Diels-Alder reaction containing a NIR fluorophore and suitable for in vivo infrared imaging.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 160E0 | 1 mg | $125 | in stock | |
| 260E0 | 5 mg | $325 | in stock | |
| 460E0 | 25 mg |
$510
|
in stock | |
| 560E0 | 50 mg |
$895
|
in stock | |
| 660E0 | 100 mg |
$1490
|
in stock |
FAM tetrazine, 5-isomer
FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 141E0 | 1 mg | $110 | in stock | |
| 241E0 | 5 mg | $210 | in stock | |
| 441E0 | 25 mg |
$410
|
in stock | |
| 541E0 | 50 mg |
$695
|
in stock | |
| 641E0 | 100 mg |
$1190
|
in stock |
FAM tetrazine, 6-isomer
This molecule is a conjugate of bright fluorophore FAM (fluorescein) and tetrazine, a reactive group that reacts with trans-cycloalkenes in a reaction called IEDDA (inverse electron demand Diels-Alder reaction).
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 151E0 | 1 mg | $110 | in stock | |
| 251E0 | 5 mg | $210 | in stock | |
| 451E0 | 25 mg |
$410
|
in stock | |
| 551E0 | 50 mg |
$695
|
in stock | |
| 651E0 | 100 mg |
$1190
|
in stock |
ROX tetrazine, 5-isomer
A tetrazine derivative of bright red-emitting dye ROX (Rhodamine X, Rhodamine 101) for copper-free bioconjugation. Pure 5-isomer.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 112E0 | 1 mg | $110 | in stock | |
| 212E0 | 5 mg | $210 | in stock | |
| 412E0 | 25 mg |
$410
|
in stock | |
| 512E0 | 50 mg |
$695
|
in stock | |
| 612E0 | 100 mg |
$1190
|
in stock |
sulfo-Cyanine3 tetrazine
Water-soluble sulfo-Cyanine3 dye tetrazine derivative for TCO ligation labeling with trans-cyclooctenes.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 113E0 | 1 mg | $125 | in stock | |
| 213E0 | 5 mg | $325 | in stock | |
| 313E0 | 10 mg |
$470
|
in stock | |
| 413E0 | 25 mg |
$850
|
in stock | |
| 513E0 | 50 mg |
$1490
|
in stock | |
| 613E0 | 100 mg |
$1990
|
in stock |
sulfo-Cyanine5 tetrazine
Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 133E0 | 1 mg | $125 | in stock | |
| 233E0 | 5 mg | $325 | in stock | |
| 333E0 | 10 mg |
$470
|
in stock | |
| 433E0 | 25 mg |
$850
|
in stock | |
| 533E0 | 50 mg |
$1490
|
in stock | |
| 633E0 | 100 mg |
$1990
|
in stock |
sulfo-Cyanine5.5 tetrazine
Tetrazine derivative of water-soluble far-red emitting fluorescent dye sulfo-Cyanine5.5 for TCO ligation with trans-cyclooctenes and other strained olefins.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 173E0 | 1 mg | $125 | in stock | |
| 273E0 | 5 mg | $325 | in stock | |
| 473E0 | 25 mg |
$850
|
in stock | |
| 573E0 | 50 mg |
$1490
|
in stock | |
| 673E0 | 100 mg |
$1990
|
in stock |
sulfo-Cyanine7 tetrazine
Near infrared, water soluble dye methyltetrazine for the conjugation with strained cycloalkenes in TCO ligation reaction.
Show pricing
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 153E0 | 1 mg | $125 | in stock | |
| 253E0 | 5 mg | $325 | in stock | |
| 453E0 | 25 mg |
$850
|
in stock | |
| 553E0 | 50 mg |
$1490
|
in stock | |
| 653E0 | 100 mg |
$1990
|
in stock |
Tetrazine-PEG3-OH
Tetrazine-PEG3-OH is a mono-reactive triethyleneglycol with a tetrazine group for IEDDA conjugation with strained olefins.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 1978-250mg | 250 mg | $390 | in stock | |
| 1978-1g | 1 g |
$950
|
in stock |
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