Tetrazines in Reactive groups

Tetrazines (1,2,4,5-tetrazine) are a six-membered cyclic system with four nitrogen atoms. Tetrazines react extremely fast with terminal alkenes and trans-cyclooctenes in Inverse electron demand Diels-Alder ligation (IEDDA). IEDDA is the fastest cycloaddition reaction among click reactions known. It possesses exceptional selectivity and kinetics. Tetrazines also react with some strained cycloalkynes. IEDDA ligation is a fast and easy method to perform labeling or bioconjugation.

AF 430 tetrazine

Tetrazine derivative of AF 430 fluorescent dye suitable for in vitro cell labeling.
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Cat. # Quantity Price Lead time
108E0 1 mg $125.00 in stock
208E0 5 mg $325.00 in stock
308E0 10 mg $480.00 in stock
408E0 25 mg $950.00 in stock
508E0 50 mg $1625.00 in stock
608E0 100 mg $2090.00 in stock

Azide-PEG3-tetrazine

A hydrophilic bifunctional linker with azide and tetrazine function groups flanking PEG3 (triethylene glycol) spacer.
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Cat. # Quantity Price Lead time
2798-250mg 250 mg $549.00 in stock

BDP 558/568 tetrazine

Stable fluorophore that can be conjugated with trans-cyclooctene derivatives of biomolecules for their visualization.
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Cat. # Quantity Price Lead time
A74E0 1 mg $125.00 in stock
B74E0 5 mg $260.00 in stock
C74E0 10 mg $325.00 in stock
D74E0 25 mg $510.00 in stock
E74E0 50 mg $895.00 in stock
F74E0 100 mg $1490.00 in stock

BDP 576/589 tetrazine

Tetrazine derivative of BDP 576/589 hydrophobic dye for conjugation with trans-cyclooctenes and cyclopropenes in the TCO ligation reaction.
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Cat. # Quantity Price Lead time
1G4E0 1 mg $110.00 in stock
2G4E0 5 mg $290.00 in stock
3G4E0 10 mg $450.00 in stock
4G4E0 25 mg $690.00 in stock
5G4E0 50 mg $1270.00 in stock
6G4E0 100 mg $1990.00 in stock

BDP 581/591 tetrazine

BDP 581/591 is a borondipyrromethene dye with tetrazine group for the inverse electron demand Diels-Alder (IEDDA) ligation.
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Cat. # Quantity Price Lead time
164E0 1 mg $110.00 in stock
264E0 5 mg $290.00 in stock
464E0 25 mg $690.00 in stock
564E0 50 mg $1270.00 in stock
664E0 100 mg $1990.00 in stock

BDP 630/650 tetrazine

BDP 630/650 is a borondipyrromethene dye for Cyanine5 channel. This is a tetrazine derivative for the coupling with strained cycloalkenes.
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Cat. # Quantity Price Lead time
154E0 1 mg $110.00 in stock
254E0 5 mg $290.00 in stock
454E0 25 mg $690.00 in stock
554E0 50 mg $1270.00 in stock
654E0 100 mg $1990.00 in stock

BDP FL tetrazine

BDP FL tetrazine (methyltetrazine) is a reactive dye for the inverse electron demand Diels-Alder (IEDDA) reaction with trans-cyclooctenes, cyclopropenes, and other strained cycloolefines. BDP FL is a bright and photostable dye for the 488 nm fluorescein (FAM) channel.
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Cat. # Quantity Price Lead time
114E0 1 mg $110.00 in stock
214E0 5 mg $290.00 in stock
414E0 25 mg $690.00 in stock
514E0 50 mg $1270.00 in stock
614E0 100 mg $1990.00 in stock

BDP R6G tetrazine

BDP R6G tetrazine is a borondipyrromethene dye with absorption and emission wavelengths similar to rhodamine 6G. It contains tetrazine fragment for IEDDA ligation.
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Cat. # Quantity Price Lead time
144E0 1 mg $110.00 in stock
244E0 5 mg $290.00 in stock
444E0 25 mg $690.00 in stock
544E0 50 mg $1270.00 in stock
644E0 100 mg $1990.00 in stock

BDP TMR tetrazine

A fluorophore for the TAMRA channel with a functional group that can form conjugates in click chemistry reactions (IEDDA ligation) .
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Cat. # Quantity Price Lead time
124E0 1 mg $125.00 in stock
224E0 5 mg $260.00 in stock
424E0 25 mg $510.00 in stock
524E0 50 mg $895.00 in stock
624E0 100 mg $1490.00 in stock

BDP TR tetrazine

BDP TR is a borondipyrromethene fluorophore for ROX channel. The dye produces bright fluorescent emission. Tetrazines are reactive components for the conjugation with strained cycloalkenes.
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Cat. # Quantity Price Lead time
134E0 1 mg $110.00 in stock
234E0 5 mg $290.00 in stock
434E0 25 mg $690.00 in stock
534E0 50 mg $1270.00 in stock
634E0 100 mg $1990.00 in stock

Biotin-PEG4-tetrazine

Biotin tetrazine is a reagent for copper-free click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
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Cat. # Quantity Price Lead time
3797-25mg 25 mg $210.00 in stock
3797-250mg 250 mg $1190.00 in stock

Cyanine3 tetrazine

Tetrazine derivative of the fluorophore Cyanine3. Tetrazines react extremely quickly with strained alkenes (such as trans-cyclooctenes, cyclopropenes), and some strained alkynes.
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Cat. # Quantity Price Lead time
110E0 1 mg $125.00 in stock
210E0 5 mg $260.00 in stock
410E0 25 mg $510.00 in stock
510E0 50 mg $895.00 in stock
610E0 100 mg $1490.00 in stock

Cyanine5 tetrazine

Cyanine5 is a universal red emitting dye with a very high extinction coefficient, and good quantum yield. This tetrazine derivative reacts very quickly with trans-cyclooctenes and cyclopropenes with the formation of stable conjugates.
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Cat. # Quantity Price Lead time
130E0 1 mg $125.00 in stock
230E0 5 mg $260.00 in stock
430E0 25 mg $510.00 in stock
530E0 50 mg $895.00 in stock
630E0 100 mg $1490.00 in stock

Cyanine5.5 tetrazine

A compound containing Cyanine5.5 fluorophore, a far red emitting dye, and tetrazine fragment for the conjugation with trans-cyclooctenes / cyclopropenes via TCO ligation.
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Cat. # Quantity Price Lead time
170E0 1 mg $125.00 in stock
270E0 5 mg $260.00 in stock
470E0 25 mg $510.00 in stock
570E0 50 mg $895.00 in stock
670E0 100 mg $1490.00 in stock

Cyanine7 tetrazine

Near infrared Cyanine7 dye derivative containing tetrazine group for TCO ligation.
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Cat. # Quantity Price Lead time
150E0 1 mg $125.00 in stock
250E0 5 mg $325.00 in stock
450E0 25 mg $510.00 in stock
550E0 50 mg $895.00 in stock
650E0 100 mg $1490.00 in stock

Cyanine7.5 tetrazine

Cyanine7.5 tetrazine is a tetrazine derivative for TCO ligation and Diels-Alder reaction containing a NIR fluorophore and suitable for in vivo infrared imaging.
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Cat. # Quantity Price Lead time
160E0 1 mg $125.00 in stock
260E0 5 mg $325.00 in stock
460E0 25 mg $510.00 in stock
560E0 50 mg $895.00 in stock
660E0 100 mg $1490.00 in stock

FAM tetrazine, 5-isomer

FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.
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Cat. # Quantity Price Lead time
141E0 1 mg $110.00 in stock
241E0 5 mg $210.00 in stock
441E0 25 mg $410.00 in stock
541E0 50 mg $695.00 in stock
641E0 100 mg $1190.00 in stock

FAM tetrazine, 6-isomer

This molecule is a conjugate of bright fluorophore FAM (fluorescein) and tetrazine, a reactive group that reacts with trans-cycloalkenes in a reaction called IEDDA (inverse electron demand Diels-Alder reaction).
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Cat. # Quantity Price Lead time
151E0 1 mg $110.00 in stock
251E0 5 mg $210.00 in stock
451E0 25 mg $410.00 in stock
551E0 50 mg $695.00 in stock
651E0 100 mg $1190.00 in stock

PEG3-tetrazine

PEG3 tetrazine is a mono-reactive triethyleneglycol with a tetrazine group for IEDDA conjugation with strained olefins.
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Cat. # Quantity Price Lead time
1978-250mg 250 mg $390.00 in stock
1978-1g 1 g $950.00 in stock

ROX tetrazine, 5-isomer

A tetrazine derivative of bright red-emitting dye ROX (Rhodamine X, Rhodamine 101) for copper-free bioconjugation. Pure 5-isomer.
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Cat. # Quantity Price Lead time
112E0 1 mg $110.00 in stock
212E0 5 mg $210.00 in stock
412E0 25 mg $410.00 in stock
512E0 50 mg $695.00 in stock
612E0 100 mg $1190.00 in stock

sulfo-Cyanine3 tetrazine

Water soluble sulfo-Cyanine3 dye tetrazine derivative for TCO ligation labeling with trans-cyclooctenes.
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Cat. # Quantity Price Lead time
113E0 1 mg $125.00 in stock
213E0 5 mg $325.00 in stock
313E0 10 mg $470.00 in stock
413E0 25 mg $850.00 in stock
513E0 50 mg $1490.00 in stock
613E0 100 mg $1990.00 in stock

sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.
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Cat. # Quantity Price Lead time
133E0 1 mg $125.00 in stock
233E0 5 mg $325.00 in stock
333E0 10 mg $470.00 in stock
433E0 25 mg $850.00 in stock
533E0 50 mg $1490.00 in stock
633E0 100 mg $1990.00 in stock

sulfo-Cyanine5.5 tetrazine

Tetrazine derivative of water-soluble far-red emitting fluorescent dye sulfo-Cyanine5.5 for TCO ligation with trans-cyclooctenes and other strained olefins.
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Cat. # Quantity Price Lead time
173E0 1 mg $125.00 in stock
273E0 5 mg $325.00 in stock
473E0 25 mg $850.00 in stock
573E0 50 mg $1490.00 in stock
673E0 100 mg $1990.00 in stock

sulfo-Cyanine7 tetrazine

Near infrared, water soluble dye methyltetrazine for the conjugation with strained cycloalkenes in TCO ligation reaction.
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Cat. # Quantity Price Lead time
153E0 1 mg $125.00 in stock
253E0 5 mg $325.00 in stock
453E0 25 mg $850.00 in stock
553E0 50 mg $1490.00 in stock
653E0 100 mg $1990.00 in stock

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