Cyanine5 tetrazine

Cat. # Quantity Price Lead time
130E0 1 mg $110.00 in stock
230E0 5 mg $290.00 in stock
430E0 25 mg $690.00 in stock
530E0 50 mg $1270.00 in stock
630E0 100 mg $1990.00 in stock

Tetrazine-cyclooctene (TCO) ligation is one of the fastest bioconjugation reactions known to date. In order to use it for fluorescent labeling, a fluorescent reporter molecule bearing one of the reacting groups is necessary.

Cyanine5 tetrazine is a molecule bearing Cyanine5 fluorophore, and tetrazine moiety. Cyanine5 is a very popular fluorophore compatible with numerous instruments.

Absorption and emission spectra of Cyanine5

Absorption and emission spectra of Cyanine5

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Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.
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Cyanine3 tetrazine

Tetrazine derivative of the fluorophore Cyanine3. Tetrazines react extremely quickly with strained alkenes (such as trans-cyclooctenes, cyclopropenes), and some strained alkynes.

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

General properties

Appearance: dark blue solid
Mass spec M+ increment: 637.4
Molecular weight: 811.84
Molecular formula: C42H48N7F6OP
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04
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