Cyanine5 tetrazine

Tetrazines Copper-free click chemistry Cyanine5

Cat. #	Quantity	Price	Lead time
130E0	1 mg	$125	in stock
230E0	5 mg	$260	in stock
430E0	25 mg	$510	in stock
530E0	50 mg	$895	in stock
630E0	100 mg	$1490	in stock

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Tetrazine-cyclooctene (TCO) ligation is one of the fastest bioconjugation reactions known to date. In order to use it for fluorescent labeling, a fluorescent reporter molecule bearing one of the reacting groups is necessary.

Cyanine5 tetrazine is a molecule bearing Cyanine5 fluorophore, and tetrazine moiety. Cyanine5 is a very popular fluorophore compatible with numerous instruments.

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Absorption and emission spectra of Cyanine5

General properties

Appearance:	dark blue solid
Mass spec M+ increment:	637.4
Molecular weight:	811.84
Molecular formula:	C₄₂H₄₈N₇F₆OP
Solubility:	good in DMF, DMSO, DCM
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	646
ε, L⋅mol⁻¹⋅cm⁻¹:	250000
Emission maximum, nm:	662
Fluorescence quantum yield:	0.2
CF₂₆₀:	0.03
CF₂₈₀:	0.04

Product citations

Santiana, J.J. ; Sawant, S.S.; Gomez, N.; Rouge, J. L. Multi-Layered Stimuli Responsive DNA Micelles for the Stepwise Controlled Release of Small Molecules. Journal of Materials Chemistry B, 2022, 10(37), 7518–7526. doi: 10.1039/D1TB02722K