Cycloalkyne in Reactive groups
Strained cycloalkynes, like cyclooctynes, react quickly with azides in a reaction called spAAC, strain promoted alkyne-azide cycloaddition. The reaction does not require catalyst, it is very rapid and high yielding. The process is useful for the conjugation of different classes of molecules even in vivo.
There is a balance between reactivity and stability of cycloalkynes. Azodibenzocyclooctynes (DBCO, ADIBO) are cyclooctyne derivatives that are characterized by excellent reaction kinetics, and very good stability.
Cyanine3 DBCO
Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper free Click chemistry.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A10F0 | 1 mg | $110.00 | stock | |
| B10F0 | 5 mg | $210.00 | stock | |
| C10F0 | 10 mg | $310.00 | stock | |
| D10F0 | 25 mg |
$410.00 |
stock | |
| E10F0 | 50 mg |
$695.00 |
stock | |
| F10F0 | 100 mg |
$1190.00 |
stock |
Cyanine5 DBCO
Cyanine5 dye with dibenzocyclooctyne (DBCO) functional group for copper free Click chemistry.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A30F0 | 1 mg | $110.00 | stock | |
| B30F0 | 5 mg | $210.00 | stock | |
| C30F0 | 10 mg | $310.00 | stock | |
| D30F0 | 25 mg |
$410.00 |
stock | |
| E30F0 | 50 mg |
$695.00 |
stock | |
| F30F0 | 100 mg |
$1190.00 |
stock |
Cyanine7 DBCO
NIR fluorescent dye functionalized with cyclooctyne moiety for copper free Click chemistry conjugation with azides.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A50F0 | 1 mg | $110.00 | stock | |
| B50F0 | 5 mg | $210.00 | stock | |
| C50F0 | 10 mg | $310.00 | stock | |
| D50F0 | 25 mg |
$410.00 |
stock | |
| E50F0 | 50 mg |
$695.00 |
21 days | |
| F50F0 | 100 mg |
$1190.00 |
21 days |
DBCO NHS ester
Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 34720 | 10 mg | $60.00 | stock | |
| 44720 | 25 mg | $95.00 | stock | |
| 54720 | 50 mg | $145.00 | stock | |
| 64720 | 100 mg | $210.00 | stock | |
| 94720 | 1 g |
$1190.00 |
stock |
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