Cycloalkyne in Reactive groups
Strained cycloalkynes, like cyclooctynes, react quickly with azides in a reaction called spAAC, strain promoted alkyne-azide cycloaddition. The reaction does not require catalyst, it is very rapid and high yielding. The process is useful for the conjugation of different classes of molecules even in vivo.
There is a balance between reactivity and stability of cycloalkynes. Azodibenzocyclooctynes (DBCO, ADIBO) are cyclooctyne derivatives that are characterized by excellent reaction kinetics, and very good stability.
BDP 581/591 DBCO
BDP 581/591 is a borondipyrromethene dye that can be used not only as a fluorescent dye, but also as a ROS probe. It can be conjugated with azides using copper free Click chemistry.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A64F0 | 1 mg | $110.00 | in stock | |
| B64F0 | 5 mg | $210.00 | in stock | |
| C64F0 | 10 mg | $310.00 | in stock | |
| D64F0 | 25 mg |
$410.00
|
in stock | |
| E64F0 | 50 mg |
$695.00
|
in stock | |
| F64F0 | 100 mg |
$1190.00
|
in stock |
BDP FL DBCO
BDP FL DBCO is a dye cyclooctyne for copper free Click chemistry reaction with azides. Absorption and emission wavelengths of BDP FL correspond to those of fluorescein (FAM), but BDP FL is significantly more photostable.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A14F0 | 1 mg | $110.00 | in stock | |
| B14F0 | 5 mg | $210.00 | in stock | |
| C14F0 | 10 mg | $310.00 | in stock | |
| D14F0 | 25 mg |
$410.00
|
in stock | |
| E14F0 | 50 mg |
$695.00
|
in stock | |
| F14F0 | 100 mg |
$1190.00
|
in stock |
BDP R6G DBCO
A derivative of BDP R6G dye with azodibenzocyclooctyne (DBCO or ADIBO) for copper free Click chemistry conjugation with azides.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A44F0 | 1 mg | $110.00 | in stock | |
| B44F0 | 5 mg | $210.00 | in stock | |
| C44F0 | 10 mg | $310.00 | in stock | |
| D44F0 | 25 mg |
$410.00
|
in stock | |
| E44F0 | 50 mg |
$695.00
|
in stock | |
| F44F0 | 100 mg |
$1190.00
|
in stock |
Cyanine3 DBCO
Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper free Click chemistry.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A10F0 | 1 mg | $110.00 | 5 days | |
| B10F0 | 5 mg | $210.00 | in stock | |
| C10F0 | 10 mg | $310.00 | in stock | |
| D10F0 | 25 mg |
$410.00
|
in stock | |
| E10F0 | 50 mg |
$695.00
|
in stock | |
| F10F0 | 100 mg |
$1190.00
|
in stock |
Cyanine5 DBCO
Cyanine5 dye with dibenzocyclooctyne (DBCO) functional group for copper free Click chemistry.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A30F0 | 1 mg | $110.00 | in stock | |
| B30F0 | 5 mg | $210.00 | in stock | |
| C30F0 | 10 mg | $310.00 | in stock | |
| D30F0 | 25 mg |
$410.00
|
in stock | |
| E30F0 | 50 mg |
$695.00
|
in stock | |
| F30F0 | 100 mg |
$1190.00
|
in stock |
Cyanine5.5 DBCO
Cyanine5.5 is a far-red / NIR emitting dye that is useful for bioimaging studies. Cyanine5.5 DBCO is a derivative of the dye with a cycloalkyne moiety for Copper free Click chemistry.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A70F0 | 1 mg | $110.00 | in stock | |
| B70F0 | 5 mg | $210.00 | in stock | |
| C70F0 | 10 mg | $310.00 | in stock | |
| D70F0 | 25 mg |
$410.00
|
in stock | |
| E70F0 | 50 mg |
$695.00
|
in stock | |
| F70F0 | 100 mg |
$1190.00
|
in stock |
Cyanine7 DBCO
NIR fluorescent dye functionalized with cyclooctyne moiety for copper free Click chemistry conjugation with azides.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A50F0 | 1 mg | $110.00 | in stock | |
| B50F0 | 5 mg | $210.00 | in stock | |
| C50F0 | 10 mg | $310.00 | in stock | |
| D50F0 | 25 mg |
$410.00
|
in stock | |
| E50F0 | 50 mg |
$695.00
|
in stock | |
| F50F0 | 100 mg |
$1190.00
|
in stock |
DBCO NHS ester
Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 34720 | 10 mg | $60.00 | 5 days | |
| 44720 | 25 mg | $95.00 | in stock | |
| 54720 | 50 mg | $145.00 | in stock | |
| 64720 | 100 mg | $210.00 | in stock | |
| 94720 | 1 g |
$1190.00
|
21 days | |
| K4720 | 5 g |
$3570.00
|
21 days | |
| N4720 | 25 g |
please inquire
|
21 days |
FAM DBCO, 6-isomer
Cyclooctyne derivative of fluorescein (FAM) for copper free Click chemistry reaction with azides. Contains pure 6-isomer of fluorescein.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 151F0 | 1 mg | $110.00 | in stock | |
| 251F0 | 5 mg | $160.00 | in stock | |
| 451F0 | 25 mg | $210.00 | in stock | |
| 551F0 | 50 mg | $270.00 | in stock | |
| 651F0 | 100 mg |
$420.00
|
in stock |
ROX DBCO, 5-isomer
ROX (rhodamine X) is a bright rhodamine dye. This is a DBCO (dibenzocyclooctyne) derivative that has high reactivity against azides.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 112F0 | 1 mg | $110.00 | in stock | |
| 212F0 | 5 mg | $290.00 | in stock | |
| 412F0 | 25 mg |
$690.00
|
in stock | |
| 512F0 | 50 mg |
$1270.00
|
in stock | |
| 612F0 | 100 mg |
$1990.00
|
in stock |
sulfo-Cyanine3 DBCO
Sulfo-Cyanine3 DBCO is a cycloalkyne derivative of water soluble, general purpose fluorophore sulfo-Cyanine3 for Click Chemistry.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 113F0 | 1 mg | $110.00 | in stock | |
| 213F0 | 5 mg | $290.00 | in stock | |
| 413F0 | 25 mg |
$690.00
|
in stock | |
| 513F0 | 50 mg |
$1270.00
|
in stock | |
| 613F0 | 100 mg |
$1990.00
|
in stock |
sulfo-Cyanine5 DBCO
Water soluble cycloalkyne for copper free Click chemistry reaction with azides. A derivative of sulfo-Cyanine5 aka Cy5.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 133F0 | 1 mg | $110.00 | in stock | |
| 233F0 | 5 mg | $290.00 | in stock | |
| 433F0 | 25 mg |
$690.00
|
in stock | |
| 533F0 | 50 mg |
$1270.00
|
in stock | |
| 633F0 | 100 mg |
$1990.00
|
in stock |
sulfo-Cyanine5.5 DBCO
Sulfo-Cyanine5.5 DBCO is a far-red, water-soluble reagent for copper-free reaction with azides.
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| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 173F0 | 1 mg | $110.00 | in stock | |
| 273F0 | 5 mg | $290.00 | in stock | |
| 473F0 | 25 mg |
$690.00
|
in stock | |
| 573F0 | 50 mg |
$1270.00
|
in stock | |
| 673F0 | 100 mg |
$1990.00
|
in stock |
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