Cyanine5 DBCO
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
A30F0 | 1 mg | $110.00 | in stock | |
B30F0 | 5 mg | $210.00 | in stock | |
C30F0 | 10 mg | $310.00 | in stock | |
D30F0 | 25 mg |
$410.00
|
in stock | |
E30F0 | 50 mg |
$695.00
|
in stock | |
F30F0 | 100 mg |
$1190.00
|
in stock |
A derivative of Cyanine5 red-emitting fluorophore possessing DBCO (dibenzocyclooctyne, also known as ADIBO, azodibenzocyclooctyne) group for copper free Click chemistry.
Strained cycloalkynes, such as cyclooctynes, react with azides very rapidly in the absence of copper catalyst in a strain promoted alkyne azide cycloaddition (spAAC). This reaction is very fast, mild, and biocompatible.
Compared to other cycloalkynes, DBCO provide among the fastest reaction kinetics, still possessing good stability.
Absorption and emission spectra of Cyanine5

Customers also purchased with this product
Sulfo-Cyanine5 amine
Sulfonated Cyanine5 amine derivative, for the conjugation with electrophiles, and enzymatic transamination labeling.Sulfo-Cyanine5 azide
Water soluble sulfo-Cyanine5 fluorescent dye azide for Click Chemistry.Cyanine5 alkyne
Cyanine5 alkyne is an alkyne dye for Click Chemistry.General properties
Appearance: | dark blue solid |
Mass spec M+ increment: | 928.4 |
Molecular weight: | 929.03 |
Molecular formula: | C53H59N4F6O2P |
Solubility: | good in DMF, DMSO, chlorinated organic solvents, practically insoluble in water (<1 uM, < 1 mg/L) |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation maximum, nm: | 646 |
ε, L⋅mol−1⋅cm−1: | 250000 |
Emission maximum, nm: | 662 |
Fluorescence quantum yield: | 0.2 |
CF260: | 0.03 |
CF280: | 0.04 |
Product citations
- Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
- Qiu, C.-X.; Bai, X.-F.; Shen, Y.; Zhou, Z.; Pan, L.-Q.; Xu, Y.-C.; Zhao, W.-B.; Chen, S.-Q. Specific Inhibition of Tumor Growth by T Cell Receptor-Drug Conjugates Targeting Intracellular Cancer-Testis Antigen NY-ESO-1/LAGE-1. Bioconjugate Chemistry, 2020, 31(12), 2767–2778. doi: 10.1021/acs.bioconjchem.0c00548
- Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
- Liu, W.; Zhao, W.; Bai, X.; Jin, S.; Li, Y.; Qiu, C.; Pan, L.; Ding, D.; Xu, Y.; Zhou, Z.; Chen, S. High antitumor activity of Sortase A-generated anti-CD20 antibody fragment drug conjugates. European Journal of Pharmaceutical Sciences, 2019, 134, 81–92. doi: 10.1016/j.ejps.2019.04.015
