Cyanine5 DBCO
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A30F0 | 1 mg | $110.00 | in stock | |
| B30F0 | 5 mg | $210.00 | in stock | |
| C30F0 | 10 mg | $310.00 | in stock | |
| D30F0 | 25 mg |
$410.00
|
in stock | |
| E30F0 | 50 mg |
$695.00
|
in stock | |
| F30F0 | 100 mg |
$1190.00
|
in stock |
A derivative of Cyanine5 red-emitting fluorophore possessing DBCO (dibenzocyclooctyne, also known as ADIBO, azodibenzocyclooctyne) group for copper free Click chemistry.
Strained cycloalkynes, such as cyclooctynes, react with azides very rapidly in the absence of copper catalyst in a strain promoted alkyne azide cycloaddition (spAAC). This reaction is very fast, mild, and biocompatible.
Compared to other cycloalkynes, DBCO provide among the fastest reaction kinetics, still possessing good stability.
Absorption and emission spectra of Cyanine5
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Cyanine5 alkyne
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Cyanine5 carboxylic acid, unactivated dye.
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BDP 581/591 azide
BDP 581/591 is a relatively hydrophobic borondipyrromethene fluorophore that can be used as a probe for ROS species, or fluorescence polarization tracer. This is an azide derivative for Click chemistry.General properties
| Appearance: | dark blue solid |
| Mass spec M+ increment: | 928.4 |
| Molecular weight: | 929.03 |
| Molecular formula: | C53H59N4F6O2P |
| Solubility: | good in DMF, DMSO, chlorinated organic solvents, practically insoluble in water (<1 uM, < 1 mg/L) |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation maximum, nm: | 646 |
| ε, L⋅mol−1⋅cm−1: | 250000 |
| Emission maximum, nm: | 662 |
| Fluorescence quantum yield: | 0.2 |
| CF260: | 0.03 |
| CF280: | 0.04 |
Product citations
- Liu, W.; Zhao, W.; Bai, X.; Jin, S.; Li, Y.; Qiu, C.; Pan, L.; Ding, D.; Xu, Y.; Zhou, Z.; Chen, S. High antitumor activity of Sortase A-generated anti-CD20 antibody fragment drug conjugates. European Journal of Pharmaceutical Sciences, 2019, 134, 81–92. doi: 10.1016/j.ejps.2019.04.015
Cy® is a trademark of GE Healthcare.
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