STP esters in Reactive groups

Primary or secondary amino groups are ubiquitous in biomolecules. They are present in proteins and peptides as ε-amino groups of lysines and N-terminal amino groups. Many natural and synthetic small molecules are amines, and DNAs with amino groups can be prepared by solid phase synthesis and enzymatically.

Amino groups can be modified by acylation with various activated carbonyl compounds. The most common for these purposes are N-hydroxysuccinimide esters (NHS esters) and sulfotetrafluorophenyl ethers (STP ethers).

STP ethers are reactive derivatives that react efficiently with primary amines to form the same acylation products as NHS esters. They are dramatically more water-soluble than the corresponding NHS esters, making them ideal for labeling biomolecules in an aqueous environment.

DBCO-STP ester

Activated ester for modification of proteins/antibodies/peptides followed by introduction into copper-free click chemistry reaction.

Show pricing

Cat. #	Quantity	Price	Lead time
2584-10mg	10 mg	$90	in stock
2584-25mg	25 mg	$180	in stock
2584-100mg	100 mg	$450	in stock
2584-500mg	500 mg	$1700	in stock
2584-1g	1 g	$3000	in stock
2584-5g	5 g	please inquire	in stock