Cycloalkynes

Dibenzocyclooctyne (DBCO, ADIBO) is one of the most reactive cycloalkynes for copper-free click reaction (SPAAC, strain-promoted azide-alkyne cycloaddition). The rate of interaction of DBCO with azides is significantly higher than that of other cyclooctynes, as well as Cu-catalyzed click reaction (CuAAC). Unlike other cyclooctynes, DBCO does not interact with tetrazines, which makes it possible to use it in bioorthogonal reactions together with trans-cyclooctenes and tetrazines.

AF 488 DBCO

Dibenzocyclooctyne (DBCO, ADIBO) containing the green fluorophore AF 488 for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples. Pure 5-isomer.
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Cat. # Quantity Price Lead time
118F0 1 mg $140 in stock
218F0 5 mg $450 in stock
418F0 25 mg $1460 in stock
518F0 50 mg $1890 in stock
618F0 100 mg $2640 in stock
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AF 568 DBCO

Dibenzocyclooctyne (DBCO, ADIBO) containing the orange fluorophore AF 568 for cooper-free labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples.
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Cat. # Quantity Price Lead time
1158F0 1 mg $140 in stock
2158F0 5 mg $450 in stock
4158F0 25 mg $1460 in stock
5158F0 50 mg $1890 in stock
6158F0 100 mg $2990 in stock
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AF 647 DBCO

Dibenzocyclooctyne (DBCO, ADIBO) derivative of the far red fluorophore AF 647 for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples.
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Cat. # Quantity Price Lead time
1G8F0 1 mg $140 21 days
2G8F0 5 mg $450 21 days
4G8F0 25 mg $1460 21 days
5G8F0 50 mg $1890 21 days
6G8F0 100 mg $2990 21 days
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BDP 558/568 DBCO

BDP 558/568 DBCO is a bright and photostable dye with emission in the yellow spectrum range. It contains a cyclooctyne substituting group (i.e. DBCO), which can react with various azides in Click Chemistry reactions.
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Cat. # Quantity Price Lead time
174F0 1 mg $125 in stock
274F0 5 mg $260 in stock
374F0 10 mg $325 in stock
474F0 25 mg $510 in stock
574F0 50 mg $895 in stock
674F0 100 mg $1490 in stock
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BDP 581/591 DBCO

BDP 581/591 is a borondipyrromethene dye that can be used not only as a fluorescent dye, but also as a ROS probe. It can be conjugated with azides using copper-free click chemistry.
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Cat. # Quantity Price Lead time
A64F0 1 mg $125 in stock
B64F0 5 mg $260 in stock
C64F0 10 mg $325 in stock
D64F0 25 mg $510 in stock
E64F0 50 mg $895 in stock
F64F0 100 mg $1490 in stock
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BDP 650/665 DBCO

This red-fluorescent dye contains a substituting group for copper-free click chemistry.
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Cat. # Quantity Price Lead time
AE4F0 1 mg $125 in stock
BE4F0 5 mg $260 in stock
CE4F0 10 mg $325 in stock
DE4F0 25 mg $510 in stock
EE4F0 50 mg $895 in stock
FE4F0 100 mg $1490 in stock
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BDP FL DBCO

BDP FL DBCO is a dye cyclooctyne for copper-free click chemistry reactions with azides. Its absorption and emission wavelengths correspond to those of fluorescein (FAM), but BDP FL is significantly more photostable.
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Cat. # Quantity Price Lead time
A14F0 1 mg $125 in stock
B14F0 5 mg $260 in stock
C14F0 10 mg $325 in stock
D14F0 25 mg $510 in stock
E14F0 50 mg $895 in stock
F14F0 100 mg $1490 in stock
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BDP R6G DBCO

A derivative of BDP R6G dye with azodibenzocyclooctyne (DBCO or ADIBO) for copper-free click chemistry conjugation with azides.
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Cat. # Quantity Price Lead time
A44F0 1 mg $125 in stock
B44F0 5 mg $260 in stock
C44F0 10 mg $325 in stock
D44F0 25 mg $510 in stock
E44F0 50 mg $895 in stock
F44F0 100 mg $1490 in stock
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BDP TMR DBCO

This yellow-orange-fluorescent boron dipyrromethene dye contains a DBCO substituting group for participation in click chemistry reactions.
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Cat. # Quantity Price Lead time
124F0 1 mg $125 in stock
224F0 5 mg $260 in stock
424F0 25 mg $510 in stock
524F0 50 mg $895 in stock
624F0 100 mg $1490 in stock
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BDP TR DBCO

A dye with a dibenzocyclooctyne substituting group for the ROX channel.
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Cat. # Quantity Price Lead time
1D4F0 1 mg $125 in stock
2D4F0 5 mg $260 in stock
4D4F0 25 mg $510 in stock
5D4F0 50 mg $895 in stock
6D4F0 100 mg $1490 in stock
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Cyanine3.5 DBCO

Cyclooctyne derivative of Cyanine3.5 dye, which easily reacts with various azides resulting in stable conjugates.
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Cat. # Quantity Price Lead time
A20F0 1 mg $125 in stock
B20F0 5 mg $260 in stock
C20F0 10 mg $325 in stock
D20F0 25 mg $510 in stock
E20F0 50 mg $895 in stock
F20F0 100 mg $1490 in stock
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Cyanine3B DBCO

Dibenzocyclooctyne (DBCO, ADIBO) containing Cyanine3B fluorophore for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples.
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Cat. # Quantity Price Lead time
193F0 1 mg $369 in stock
293F0 5 mg $727 in stock
493F0 25 mg $1950 in stock
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Cyanine3 DBCO

Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper-free click chemistry.
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Cat. # Quantity Price Lead time
A10F0 1 mg $125 in stock
B10F0 5 mg $260 in stock
C10F0 10 mg $325 in stock
D10F0 25 mg $510 in stock
E10F0 50 mg $895 in stock
F10F0 100 mg $1490 in stock
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Cyanine5.5 DBCO

Cyanine5.5 is a far-red / NIR emitting dye that is useful for bioimaging studies. Cyanine5.5 DBCO is a derivative of the dye with a cycloalkyne moiety for copper-free click chemistry.
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Cat. # Quantity Price Lead time
A70F0 1 mg $125 in stock
B70F0 5 mg $260 in stock
C70F0 10 mg $325 in stock
D70F0 25 mg $510 in stock
E70F0 50 mg $895 in stock
F70F0 100 mg $1490 in stock
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Cyanine5 DBCO

Cyanine5 dye with dibenzocyclooctyne (DBCO) functional group for copper-free click chemistry.
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Cat. # Quantity Price Lead time
A30F0 1 mg $125 in stock
B30F0 5 mg $260 in stock
C30F0 10 mg $325 in stock
D30F0 25 mg $510 in stock
E30F0 50 mg $895 in stock
F30F0 100 mg $1490 in stock
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Cyanine7 DBCO

NIR fluorescent dye functionalized with cyclooctyne moiety for copper free click chemistry conjugation with azides.
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Cat. # Quantity Price Lead time
A50F0 1 mg $125 in stock
B50F0 5 mg $260 in stock
C50F0 10 mg $325 in stock
D50F0 25 mg $510 in stock
E50F0 50 mg $895 in stock
F50F0 100 mg $1490 in stock
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FAM DBCO, 6-isomer

Cyclooctyne derivative of fluorescein (FAM) for copper-free click chemistry reaction with azides. Pure 6-isomer of fluorescein.
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Cat. # Quantity Price Lead time
151F0 1 mg $110 in stock
251F0 5 mg $160 in stock
451F0 25 mg $260 in stock
551F0 50 mg $370 in stock
651F0 100 mg $525 5 days