Cycloalkynes

Dibenzocyclooctyne (DBCO, ADIBO) is one of the most reactive cycloalkynes for copper-free click reaction (SPAAC, strain-promoted azide-alkyne cycloaddition). The rate of interaction of DBCO with azides is significantly higher than that of other cyclooctynes, as well as Cu-catalyzed click reaction (CuAAC). Unlike other cyclooctynes, DBCO does not interact with tetrazines, which makes it possible to use it in bioorthogonal reactions together with trans-cyclooctenes and tetrazines.

AF 488 DBCO

Dibenzocyclooctyne (DBCO, ADIBO) containing the green fluorophore AF 488 for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples. Pure 5-isomer.
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Cat. # Quantity Price Lead time
118F0 1 mg $140 in stock
218F0 5 mg $450 in stock
418F0 25 mg $1460 in stock
518F0 50 mg $1890 in stock
618F0 100 mg $2640 5 days
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AF 555 DBCO

Dibenzocyclooctyne (DBCO, ADIBO) containing the yellow fluorophore AF 555 for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples.
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Cat. # Quantity Price Lead time
1K8F0 1 mg $140 in stock
2K8F0 5 mg $450 in stock
4K8F0 25 mg $1460 in stock
5K8F0 50 mg $1890 in stock
6K8F0 100 mg $2990 in stock
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AF 568 DBCO

Dibenzocyclooctyne (DBCO, ADIBO) containing the orange fluorophore AF 568 for cooper-free labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples.
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Cat. # Quantity Price Lead time
1158F0 1 mg $140 in stock
2158F0 5 mg $450 in stock
4158F0 25 mg $1460 in stock
5158F0 50 mg $1890 in stock
6158F0 100 mg $2990 in stock
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AF 647 DBCO

Dibenzocyclooctyne (DBCO, ADIBO) derivative of the far red fluorophore AF 647 for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples.
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Cat. # Quantity Price Lead time
1G8F0 1 mg $140 in stock
2G8F0 5 mg $450 in stock
4G8F0 25 mg $1460 in stock
5G8F0 50 mg $1890 in stock
6G8F0 100 mg $2990 in stock
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BDP® 558/568 DBCO

BDP 558/568 DBCO is a bright and photostable dye with emission in the yellow spectrum range. It contains a cyclooctyne substituting group (i.e. DBCO), which can react with various azides in Click Chemistry reactions.
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Cat. # Quantity Price Lead time
174F0 1 mg $125 in stock
274F0 5 mg $260 in stock
374F0 10 mg $325 in stock
474F0 25 mg $510 in stock
574F0 50 mg $895 in stock
674F0 100 mg $1490 in stock
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BDP® 581/591 DBCO

BDP 581/591 is a borondipyrromethene dye that can be used not only as a fluorescent dye, but also as a ROS probe. It can be conjugated with azides using copper-free click chemistry.
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Cat. # Quantity Price Lead time
A64F0 1 mg $125 in stock
B64F0 5 mg $260 in stock
C64F0 10 mg $325 in stock
D64F0 25 mg $510 in stock
E64F0 50 mg $895 in stock
F64F0 100 mg $1490 in stock
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BDP® 650/665 DBCO

This red-fluorescent dye contains a substituting group for copper-free click chemistry.
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Cat. # Quantity Price Lead time
AE4F0 1 mg $125 in stock
BE4F0 5 mg $260 in stock
CE4F0 10 mg $325 in stock
DE4F0 25 mg $510 in stock
EE4F0 50 mg $895 in stock
FE4F0 100 mg $1490 in stock
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BDP® FL DBCO

BDP FL DBCO is a dye cyclooctyne for copper-free click chemistry reactions with azides. Its absorption and emission wavelengths correspond to those of fluorescein (FAM), but BDP FL is significantly more photostable.
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Cat. # Quantity Price Lead time
A14F0 1 mg $125 in stock
B14F0 5 mg $260 in stock
C14F0 10 mg $325 in stock
D14F0 25 mg $510 in stock
E14F0 50 mg $895 in stock
F14F0 100 mg $1490 in stock
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BDP® R6G DBCO

A derivative of BDP R6G dye with azodibenzocyclooctyne (DBCO or ADIBO) for copper-free click chemistry conjugation with azides.
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Cat. # Quantity Price Lead time
A44F0 1 mg $125 in stock
B44F0 5 mg $260 in stock
C44F0 10 mg $325 in stock
D44F0 25 mg $510 in stock
E44F0 50 mg $895 in stock
F44F0 100 mg $1490 in stock