Cyanine3 DBCO

Cat. # Quantity Price Lead time
A10F0 1 mg $125 in stock
B10F0 5 mg $260 in stock
C10F0 10 mg $325 in stock
D10F0 25 mg $510 in stock
E10F0 50 mg $895 in stock
F10F0 100 mg $1490 in stock
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Azodibenzocyclooctyne (DBCO or ADIBO) is a stable but very reactive cycloalkyne for copper-free click chemistry.

This reagent is a conjugate of DBCO with Cyanine3 fluorophore for the non-catalyzed, strain promoted reaction with azides.

Absorption and emission spectra of Cyanine3 fluorophore

Absorption and emission spectra of Cyanine3 fluorophore

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General properties

Appearance: dark red powder
Molecular weight: 902.99
CAS number: 2692677-79-3
Molecular formula: C51H57N4O2PF6
Solubility: good in DMF, DMSO, DCM, alcohols, practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31

Product citations

  1. Tsuchiya, M.; Tachibana, N.; Hamachi, I. Flow cytometric analysis of phosphatidylcholine metabolism using organelle-selective click labeling. STAR Protocols, 2023, 4(3), 102525. doi: 10.1016/j.xpro.2023.102525
  2. Jiang, Z.; He, H.; Liu, H.; Thayumanavan, S. Azide-Terminated RAFT Polymers for Biological Applications. Current Protocols in Chemical Biology, 2020, 12(4), e85. doi: 10.1002/cpch.85
  3. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  4. Jiang, Z.; He, H.; Liu, H.; Thayumanavan, S. Cellular Uptake Evaluation of Amphiphilic Polymer Assemblies: Importance of Interplay between Pharmacological and Genetic Approaches. Biomacromolecules, 2019, 20(12), 4407–4418. doi: 10.1021/acs.biomac.9b01073
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