Cyanine3 DBCO

Cat. # Quantity Price Lead time
A10F0 1 mg $110.00 in stock
B10F0 5 mg $210.00 in stock
C10F0 10 mg $310.00 in stock
D10F0 25 mg $410.00 in stock
E10F0 50 mg $695.00 in stock
F10F0 100 mg $1190.00 in stock

Azodibenzocyclooctyne (DBCO or ADIBO) is a stable but very reactive cycloalkyne for copper free Click chemistry.

This reagent is a conjugate of DBCO with Cyanine3 fluorophore for the non-catalyzed, strain promoted reaction with azides.

Absorption and emission spectra of Cyanine3 fluorophore

Absorption and emission spectra of Cyanine3 fluorophore

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General properties

Appearance: dark red powder
Molecular weight: 902.99
Molecular formula: C51H57N4O2PF6
Solubility: good in DMF, DMSO, DCM, alcohols, practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

Product citations

  1. Jiang, Z.; He, H.; Liu, H.; Thayumanavan, S. Cellular Uptake Evaluation of Amphiphilic Polymer Assemblies: Importance of Interplay between Pharmacological and Genetic Approaches. Biomacromolecules, in press. doi: 10.1021/acs.biomac.9b01073
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