TODi-3, far-red fluorescent nucleic acid stain
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A2610 | 50 uL, 5 mM/DMSO | $85 | in stock | |
| 22610 | 200 uL, 5 mM/DMSO | $320 | in stock |
TODi-3 (Thiazole Red Homodimer, also known as TOTO®-3) is a far-red fluorescent carbocyanine dimeric dye. TODi-3 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits a significant fluorescence enhancement upon binding to dsDNA.
The bright fluorescence signal and low background make TODi-3 ideal for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in multicolor fluorescence labeling experiments. TODi-3 is non-cytotoxic and may be used for long-term monitoring of cell viability and dead cell detection in culture. The long-wavelength fluorescence of TODi-3 is well separated from green and red fluorophores, which makes it ideal for multicolor fluorescence labeling experiments.
Absorption and emission spectra of TODi-3 (DNA–dye complex)
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| Appearance: | blue solution |
| Molecular weight: | 1354.87 |
| CAS number: | 166196-17-4 |
| Molecular formula: | C53H62I4N6S2 |
| IUPAC name: | Quinolinium, 1,1′-[1,3-propanediylbis[(dimethyliminio)-3,1-propanediyl]]bis[4-[3-(3-methyl-2(3H)-benzothiazolylidene)-1-propenyl]-, tetraiodide |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 644 |
| Emission maximum, nm: | 662 |
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