Potentiometric probes

Potentiometric probes are voltage-sensitive dyes that change their spectral properties in response to electric potential changes. They allow linear measurements of the firing activity of electrically active cells: neurons, myocytes, and some secretory cells. Potentiometric dyes are used to measure spatial and temporal fluctuations in potential across the membrane of single cells and large cell populations. It also makes it possible to monitor the electrical activity inside cell organelles like mitochondria and dendritic spines, where direct electrode insertion is not feasible.

Di-4-ANEPPS, potentiometric probe

Fast-response potential-sensitive fluorescent probe for imaging functional activity of neurons and heart cells. The dye is quickly internalized by cells and is well-suited for short-term experiments.
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Cat. # Quantity Price Lead time
3429-50ug 50 ug –   in stock
3429-5mg 5 mg $225 5 days
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Di-8-ANEPPS, potentiometric probe

Fast-response potential-sensitive fluorescent probe for imaging functional activity of neurons and heart cells. The dye has more lipophilic properties than other dyes of the ANEP family, making it well-suited for long-term experiments.
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Cat. # Quantity Price Lead time
4274-50ug 50 ug –   in stock
4274-5mg 5 mg $238 in stock
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Pluronic® F-127

A nonionic detergent widely used to solubilize hydrophobic molecules such as cell-permeable AM esters of Fluo-4, Fluorica-8 calcium indicators, and Di-4-ANEPS, Di-8-ANEPS potentiometric probes and facilitate their loading into cells.
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Cat. # Quantity Price Lead time
P9050 30 mL $72 21 days
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RH 237, potentiometric probe

Fast-response potential-sensitive fluorescent probe for imaging functional activity of mitochondria, neurons, and heart cells.
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Cat. # Quantity Price Lead time
3734-5mg 5 mg $139 in stock
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