Cell biology reagents
Cell biology reagents / product groups & items in this category
Dyes and reagents for cell biology: cell markers and indicators, substances for metabolic labeling, inhibitors, etc.
Nuclear stains
Cell-membrane permeant and impermeant DNA dyes for specific staining nuclei in live or fixed cells.
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BO-TAP-1, cyan fluorescent nucleic acid stain
BO-TAP-1 is a cell-impermeant cyan fluorescent nucleic acid stain. BO-TAP-1 is chemically equivalent to BO-PRO®-1.
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BO-TAP-3, orange fluorescent nucleic acid stain
BO-TAP-3 is a cell-impermeant orange fluorescent nucleic acid stain. BO-TAP-3 is chemically equivalent to BO-PRO®-3.
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BODi-1, cyan fluorescent nucleic acid stain
BODi-1 is a cell-impermeant cyan fluorescent nucleic acid stain. BODi-1 is chemically equivalent to BOBO®-1.
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DAPI, blue fluorescent nucleic acid stain
DAPI (4′,6-diamidino-2-phenylindole) is a blue-emitting fluorescent DNA dye used for chromosome staining and as a nuclear counterstain in fluorescence microscopy and flow cytometry.
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Hoechst 33258, blue fluorescent nucleic acid stain
Hoechst 33258 is a cell-permeant blue-emitting fluorescent dsDNA dye used for staining chromosomes and nuclei in live and fixed cells.
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Hoechst 33342, blue fluorescent nucleic acid stain
Hoechst 33342 (bisbenzimide) is a cell-permeant blue-emitting fluorescent dsDNA dye used for staining chromosomes and nuclei in live and fixed cells.
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Hoechst 34580, blue fluorescent nucleic acid stain
Hoechst 34580 is a cell-permeant blue-emitting fluorescent dsDNA dye used for staining chromosomes and nuclei in live and fixed cells.
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Hoechst S769121 (Nuclear Yellow), yellow fluorescent nucleic acid stain
Hoechst S769121 (Nuclear Yellow) is a cell-permeant yellow-emitting fluorescent dsDNA dye used for staining DNA content in live and fixed cells.
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LUCS® 13, green fluorescent nucleic acid stain
LUCS 13 is a cell-permeant green fluorescent nucleic acid stain that exhibits bright, green fluorescence upon binding to nucleic acids.
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LUCS® 5, far-red fluorescent nucleic acid stain
Cell-permeant far-red fluorescent DNA dye for live and fixed cell imaging and analysis.
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PO-TAP-1, blue fluorescent nucleic acid stain
PO-TAP-1 is a cell-impermeant blue fluorescent nucleic acid stain. PO-TAP-1 is chemically equivalent to PO-PRO®-1.
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PO-TAP-3, yellow fluorescent nucleic acid stain
PO-TAP-3 is a cell-impermeant yellow fluorescent nucleic acid stain. PO-TAP-3 is chemically equivalent to PO-PRO®-3.
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PODi-1, blue fluorescent nucleic acid stain
PODi-1 is a cell-impermeant blue fluorescent nucleic acid stain. PODi-1 is chemically equivalent to POPO®-1.
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Propidium Iodide
Propidium iodide is a membrane-impermeable intercalating DNA dye for staining nuclei of death cells.
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TO-TAP-1, green fluorescent nucleic acid stain
TO-TAP-1 is a cell-impermeant green fluorescent nucleic acid stain. TO-TAP-1 is chemically equivalent to TO-PRO®-1.
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TO-TAP-3, far-red fluorescent nucleic acid stain
TO-TAP-3 is a cell-impermeant far-red fluorescent nucleic acid stain. TO-TAP-3 is chemically equivalent to TO-PRO®-3.
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TODi-1, green fluorescent nucleic acid stain
TODi-1 is a cell-impermeant green fluorescent nucleic acid stain. TODi-1 is chemically equivalent to TOTO®-1.
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TODi-3, far-red fluorescent nucleic acid stain
TODi-3 is a cell-impermeant far-red fluorescent nucleic acid stain. TODi-3 is chemically equivalent to TOTO®-3.
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TOR-G4, G-quadruplexes fluorescent probe
TOR-G4 is a fluorescent probe that allows sensitive distinction of G-quadruplexes RNA based on changes to the fluorescence lifetime of a probe upon nucleic acid binding.
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Thiazole Orange
Cyanine dye that is essentially dark in solution but has a bright fluorescence in double-stranded DNA and RNA complexes.
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YO-TAP-1, green fluorescent nucleic acid stain
YO-TAP-1 is a cell-impermeant green-fluorescent nucleic acid stain. YO-TAP-1 is chemically equivalent to YO-PRO®-1.
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YO-TAP-3, red fluorescent nucleic acid stain
YO-TAP-3 is a cell-impermeant red fluorescent nucleic acid stain. YO-TAP-3 is chemically equivalent to YO-PRO®-3.
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YODi-1, green fluorescent nucleic acid stain
YODi-1 is a cell-impermeant green-fluorescent nucleic acid stain. YODi-1 is chemically equivalent to YOYO®-1.
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YODi-3, red fluorescent nucleic acid stain
YODi-3 is a cell-impermeant red fluorescent nucleic acid stain. YODi-3 is chemically equivalent to YOYO®-3.
Plasma membrane stains
Lipophilic dyes with different spectral properties for plasma membrane staining and visualization of cell boundaries and morphology.
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Lipophilic Tracer Sampler Kit
The kit containing samplers of eight different lipophilic carbocyanine dyes.
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PKH Dyes Diluent
Diluent for PKH series of membrane labeling dyes.
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PKH2 Cell Membrane Labeling Kit
The ready-to-use kit to label cell membranes with green fluorescent PKH2 dye for evaluating cell migration or proliferation.
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PKH26 Cell Membrane Labeling Kit
The ready-to-use kit to label cell membranes with red fluorescent PKH26 dye for evaluating cell migration or proliferation.
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PKH800 Cell Membrane Labeling Kit
The ready-to-use kit to label cell membranes with near-infrared fluorescent PKH800 dye for evaluating cell migration or proliferation.
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CM-DiI, lipophilic tracer
Orange-red fluorescent lipophilic dye for membrane labeling and cell tracking. Unlike other membrane dyes, CM-DiI persists in cells after their fixation and permeabilization.
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DiA, lipophilic tracer
Wide spectrum fluorescent lipophilic dye for membrane labeling and cell tracing.
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DiD, lipophilic tracer
Far-red fluorescent lipophilic dye for membrane labeling and cell tracing.
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DiI, lipophilic tracer
Orange-red fluorescent lipophilic dye for membrane labeling and cell tracing.
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DiO, lipophilic tracer
Green fluorescent lipophilic dye for membrane labeling and cell tracing.
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DiR, lipophilic tracer
Near-infrared fluorescent lipophilic dye for membrane labeling and cell tracing.
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Laurdan (6-Dodecanoyl-2-dimethylaminonaphthalene)
Laurdan is a polarity-sensitive lipid membrane fluorescent probe. It is used for imaging lipid rafts and studying cell plasmatic membrane dynamics.
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Neuro-DiO, lipophilic tracer
Non-aggregating green fluorescent lipophilic dye for membrane labeling and cell tracing.
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RAPID DiI, lipophilic tracer
Orange-red fluorescent lipophilic dye for cell tracing with fast migration into membranes, an analog of FAST DiI™.
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RAPID DiO, lipophilic tracer
Green fluorescent lipophilic dye for cell tracing with fast migration into membranes, an analog of FAST DiO™.
Organelle stains
Reagents and kits for detecting specific cell organelles and structures in live and fixed cells.
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DND-167, blue fluorescent pH indicator
Blue fluorescent pH-sensitive dye for staining acidic organelles (lysosomes and late endosomes) in living cells.
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LumiTracker® Lyso Green
Green-fluorescent dye for visualization of lysosomes in living cells and other cell organelles with a low pH. Analog of LysoTracker™ Green DND-26.
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LumiTracker® Lyso Red
Red-fluorescent reagent for labeling and tracking lysosomes and other acidic organelles with low internal pH in live cells. Analog of LysoTracker™ Red DND-99.
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(E,E)-3,5-Bis(phenylethenyl)-BDP® lipid stain
A non-functionalized 3,5-substituted borondipyrromethene derivative with a Stokes shift of 13 nm and an emission spectrum in the red spectrum range.
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BDP® 493/503 lipid stain
BDP 493/503 is a lipophilic green fluorescent dye for the staining and tracing of cell membranes, lipids, and oils.
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BDP® 505/515 lipid stain
BDP 505/515 is a lipid staining dye for cell membranes. It has a high fluorescence quantum yield, and is very photostable.
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BDP® 630/650 lipid stain
Far-red fluorescent dye BDP 630/650 for staining of lipids and and other lipophilic compounds.
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BDP® 650/665 lipid stain
Hydrophobic borondipyrromethene dye BDP 650/665 for staining of lipids and lipophilic compounds.
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BDP® FL ceramide
Fluorescent derivative of sphingosine with emission in the green spectrum region for visualization of the Golgi apparatus in cells.
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BDP® TMR ceramide
Fluorescent derivative of sphingosine with emission in the orange spectrum region for visualization of the Golgi apparatus in cells.
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BDP® TR ceramide
Fluorescent derivative of sphingosine with emission in the red spectrum region for visualization of the Golgi apparatus in cells.
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BDP® TR methyl ester
BDP TR methyl ester is a lipophilic counterstain for GFP. Сell-permeable dye that stains mitochondria and endomembranous organelles, but not plasma membrane.
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Bis-ANS, protein conformation probe
High-affinity fluorescent probe for nonpolar cavities in proteins to monitor the formation of protein aggregates and indicate protein folding and conformational changes.
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Deep-Red Fluorescent Nissl Stain
Far-red fluorescent Nissl stain for visualization and assessment of neural tissue morphology.
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LumiTracker Mito Orange CM-H2TMRos
A cationic, orange-fluorescent dye for staining active mitochondria in live cells. CM-H2TMRos is a reduced, nonfluorescent version of the CMTMRos dye that becomes fluorescent when oxidized at the mitochondrial membrane.
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LumiTracker® ER Green
Green fluorescent stain for selective labeling of endoplasmic reticulum (ER) in live cells.
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LumiTracker® ER Red
Red fluorescent stain for selective labeling of endoplasmic reticulum (ER) in live cells.
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LumiTracker® Lyso Blue
Blue-emitting reagent for labeling and tracking lysosomes and other acidic organelles with low internal pH in live cells. Analog of LysoTracker™ Blue DND-22.
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LumiTracker® Mito Green FM
Сell-permeant cationic green-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner.
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LumiTracker® Mito JC-1
The cationic carbocyanine dye that is widely used as an indicator of mitochondrial membrane potential to study apoptosis and monitor the health of mitochondria.
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LumiTracker® Mito Orange CMTMRos
Сell-permeant, cationic, orange-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner. The stain is compatible with aldehyde fixation.
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LumiTracker® Mito Red CMXRos
Сell-permeant, cationic, red-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner. The stain is compatible with aldehyde fixation.
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LumiTracker® Mito Red FM
Сell-permeant, cationic, red-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner.
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LumiTracker® Mito Rhodamine 123
Rhodamine 123 is a cell-permeant, green-fluorescent dye that stains mitochondria in living cells in a membrane potential-dependent manner.
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LumiTracker® Mito TMRE
Tetramethylrhodamine ethyl ester (TMRE) is an orange-red fluorescent dye for staining active mitochondria and quantitate mitochondrial membrane potential in live cells.
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SynaptoProbe Green
SynaptoProbe Green is an analog of FM®1-43, a widely used green fluorescent dye for staining synaptic vesicles and studying synaptic activity in the synapses or neuromuscular junctions.
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SynaptoProbe Red
SynaptoProbe Red is an analog of FM®4-64, a widely used red fluorescent dye for staining synaptic vesicles and studying synaptic activity in the synapses or neuromuscular junctions.
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TAMRA-2,4-dinitroaniline (TMR-DN)
TAMRA-2,4-dinitroaniline is a probe for visualizing RNA in living cells.
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TOR-G4, G-quadruplexes fluorescent probe
TOR-G4 is a fluorescent probe that allows sensitive distinction of G-quadruplexes RNA based on changes to the fluorescence lifetime of a probe upon nucleic acid binding.
Cell tracing and tracking
Our dyes for anterograde and retrograde tracing of living and fixed cells and cell tracking.
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CFDA SE Cell Tracing Kit
The ready-to-use kit for fluorescent labeling and long-term tracing of cells. CFDA SE is commonly used for measuring and tracking cell divisions.
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Lipophilic Tracer Sampler Kit
The kit containing samplers of eight different lipophilic carbocyanine dyes.
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PKH Dyes Diluent
Diluent for PKH series of membrane labeling dyes.
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PKH2 Cell Membrane Labeling Kit
The ready-to-use kit to label cell membranes with green fluorescent PKH2 dye for evaluating cell migration or proliferation.
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PKH26 Cell Membrane Labeling Kit
The ready-to-use kit to label cell membranes with red fluorescent PKH26 dye for evaluating cell migration or proliferation.
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PKH800 Cell Membrane Labeling Kit
The ready-to-use kit to label cell membranes with near-infrared fluorescent PKH800 dye for evaluating cell migration or proliferation.
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(5,6)-FAM diacetate NHS ester
Amine-reactive fluorescein (FAM) derivative, a mixture of 5- and 6-isomers. The reagent becomes brightly green fluorescent once it is hydrolyzed while diffusing into cells. A fluorescent tracer.
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AF 594 biocytin
AF 594 biocytin is a cell-impermeant fixable polar tracer with red emission that can be used to examine plasma membrane permeability, pinocytosis, transport through gap junctions, and cell-cell or cell-liposome fusion.
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Biocytin hydrochloride
Lysine derivative of biotin for conjugation with avidin or streptavidin, neuroanatomical tracer.
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CM-DiI, lipophilic tracer
Orange-red fluorescent lipophilic dye for membrane labeling and cell tracking. Unlike other membrane dyes, CM-DiI persists in cells after their fixation and permeabilization.
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DiA, lipophilic tracer
Wide spectrum fluorescent lipophilic dye for membrane labeling and cell tracing.
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DiD, lipophilic tracer
Far-red fluorescent lipophilic dye for membrane labeling and cell tracing.
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DiI, lipophilic tracer
Orange-red fluorescent lipophilic dye for membrane labeling and cell tracing.
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DiO, lipophilic tracer
Green fluorescent lipophilic dye for membrane labeling and cell tracing.
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DiR, lipophilic tracer
Near-infrared fluorescent lipophilic dye for membrane labeling and cell tracing.
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Neuro-DiO, lipophilic tracer
Non-aggregating green fluorescent lipophilic dye for membrane labeling and cell tracing.
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RAPID DiI, lipophilic tracer
Orange-red fluorescent lipophilic dye for cell tracing with fast migration into membranes, an analog of FAST DiI™.
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RAPID DiO, lipophilic tracer
Green fluorescent lipophilic dye for cell tracing with fast migration into membranes, an analog of FAST DiO™.
Cell viability indicators
Reagents and ready-to-use kits for studying cell viability and apoptosis by flow cytometry and microscopy.
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Annexin V-AF 488 Apoptosis Detection Kit, with Propidium Iodide
The ready-to-use kit to label apoptotic and necrotic cells with Annexin V-AF 488 conjugate and propidium iodide.
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Annexin V-AF 647 Apoptosis Detection Kit, with Propidium Iodide
The ready-to-use kit to label apoptotic and necrotic cells with Annexin V-AF 647 conjugate and propidium iodide.
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CFDA SE Cell Tracing Kit
The ready-to-use kit for fluorescent labeling and long-term tracing of cells. CFDA SE is commonly used for measuring and tracking cell divisions.
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Mitochondrial Membrane Potential Apoptosis Kit, with LumiTracker® Mito Red CMXRos & Annexin V-AF 488
The ready-to-use kit for assaying two key indicators of apoptosis: the externalization of phosphatidylserine and alterations in mitochondrial membrane potential.
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Annexin V-AF 488 conjugate
Annexin V-AF 488 conjugate for detection of apoptotic cells by flow cytometry and fluorescence microscopy.
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Annexin V-AF 647 conjugate
Annexin V-AF 647 conjugate for detection of apoptotic cells by flow cytometry and fluorescence microscopy.
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LumiTracker® Mito JC-1
The cationic carbocyanine dye that is widely used as an indicator of mitochondrial membrane potential to study apoptosis and monitor the health of mitochondria.
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MitoCLox, mitochondrial lipid peroxidation probe
MitoCLox is a mitochondria-targeted fluorescence probe for tracing cardiolipin oxidation in vivo.
ROS indicators
Cell permeant fluorogenic dyes for detection of reactive oxygen species (ROS) in live cells by flow cytometry, microscopy, or fluorimetry.
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Singlet Oxygen Sensor Green (SOSG)
Fluorogenic probe for detecting singlet oxygen in aqueous solutions.
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6-Carboxy-H2DCFDA (6-carboxy-2',7'-dichlorodihydrofluorescein)
A reagent for detecting reactive oxygen species (ROS) in living cells. This carboxylated H2DCFDA analog has two additional negative charges that impede its leakage out of the cell.
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DAF-FM diacetate (4-amino-5-methylamino-2',7'-difluorofluorescein diacetate)
Cell-permeant, fluorescent probe for detecting and quantifying low concentrations of nitric oxide (NO).
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H2DCFDA (2′,7′-dichlorodihydrofluorescein diacetate)
A reagent for detecting reactive oxygen species in living cells.
Ion and pH indicators
Small fluorogenic molecules for indicating specific ions inside cells in vivo. Cell permeant indicators for Ca-, Fe-ions, pH, and others.
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DND-167, blue fluorescent pH indicator
Blue fluorescent pH-sensitive dye for staining acidic organelles (lysosomes and late endosomes) in living cells.
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BAPTA AM, calcium chelator
Cell-permeable acetoxymethyl ester (AM) form of BAPTA, a highly selective calcium chelator for cell signaling studies.
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Fluo-4 AM, green fluorescent calcium indicator
Fluo-4 AM is a cell-permeable calcium ion indicator that is metabolized by intracellular esterase, leading to a bright green fluorescent signal upon calcium ion binding. Fluo-4 AM is well suited for fluorometric and imaging applications.
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HMRhoNox-M, Fe(II)-selective fluorescent probe
Fe(II)-responsive turn-on fluorescent probe for monitoring fluctuations of endogenous labile iron in living cells.
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Pluronic® F-127
A nonionic detergent widely used to solubilize hydrophobic molecules such as cell-permeable AM esters of Fluo-4, Fluorica-8 calcium indicators, and Di-4-ANEPS, Di-8-ANEPS potentiometric probes and facilitate their loading into cells.
Potentiometric probes
Voltage-sensitive dyes for measurement of spatial and temporal fluctuations in membrane potential across the membrane of large cell populations, single cells, and cell organelles.
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Di-4-ANEPPS, potentiometric probe
Fast-response potential-sensitive fluorescent probe for imaging functional activity of neurons and heart cells. The dye is quickly internalized by cells and is well-suited for short-term experiments.
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Di-8-ANEPPS, potentiometric probe
Fast-response potential-sensitive fluorescent probe for imaging functional activity of neurons and heart cells. The dye has more lipophilic properties than other dyes of the ANEP family, making it well-suited for long-term experiments.
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Pluronic® F-127
A nonionic detergent widely used to solubilize hydrophobic molecules such as cell-permeable AM esters of Fluo-4, Fluorica-8 calcium indicators, and Di-4-ANEPS, Di-8-ANEPS potentiometric probes and facilitate their loading into cells.
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RH 237, potentiometric probe
Fast-response potential-sensitive fluorescent probe for imaging functional activity of mitochondria, neurons, and heart cells.
Cell type-specific markers
Small-molecule fluorescent markers for different types of cells. A fast and well-permeant to live cells and tissues alternative to antibody labeling.
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Deep-Red Fluorescent Nissl Stain
Far-red fluorescent Nissl stain for visualization and assessment of neural tissue morphology.
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LumiCell CDr20 Microglia Stain
CDr20 is a turn-on fluorescent chemical probe for specific labeling and visualizing microglia in cell cultures and live brains.
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LumiCell Reticulocyte Stain
LumiCell Reticulocyte Stain is a ready-to-use Thiazole Orange solution for determining a percentage of reticulocytes in human peripheral blood with microscopy and flow cytometry.
Immunofluorescence
Reagents for immunofluorescence applications: fluorescent labeled derivatives of tyramide for signal amplification (TSA), biotin, and streptavidin for Western Blotting, immunoassay, immunochemistry, and in situ hybridization.
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AF 488 streptavidin
AF 488 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
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AF 488 tyramide
A tyramide derivative of AF 488, a green fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
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AF 594 streptavidin
AF 594 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
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AF 594 tyramide
A tyramide derivative of AF 594, a red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
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AMCA streptavidin
AMCA conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
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sulfo-Cyanine3 streptavidin
sulfo-Cyanine3 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
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sulfo-Cyanine3 tyramide
A tyramide derivative of sulfo-Cyanine3, an orange fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
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sulfo-Cyanine3-PEG3-biotin
Conjugate of hydrophilic sulfo-Cyanine3 dye with biotin, affinity label for avidin/streptavidin.
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sulfo-Cyanine5 streptavidin
sulfo-Cyanine5 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
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sulfo-Cyanine5 tyramide
A tyramide derivative of sulfo-Cyanine5, a far-red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
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sulfo-Cyanine5-PEG3-biotin
Biotin conjugate of the far-red fluorescent sulfo-Cyanine5 dye.
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sulfo-Cyanine5.5 tyramide
A tyramide derivative of sulfo-Cyanine5.5, a far-red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
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sulfo-Cyanine7 tyramide
A tyramide derivative of sulfo-Cyanine7, a near-infrared fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
Metabolic labeling
Reagents for metabolic in vivo labeling of cells and whole organisms.
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4AZP (4-Azido-L-phenylalanine)
Unnatural L-phenylalanine derivative with an azide moiety for nascent protein synthesis detection via copper-catalyzed and copper-free click chemistry.
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5-Ethynyl-uridine (EU)
Uridine alkyne derivative for monitoring and investigation of RNA transcription in cells.
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AHA (L-Azidohomoalanine)
Noncanonical amino acid analog of methionine with an azide moiety for nascent protein synthesis detection via copper-catalyzed and copper-free click chemistry.
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Ac4GalNAl (N-(4-pentynoyl)-galactosamine-tetraacylated)
An alkyne-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
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Ac4GalNAz (N-Azidoacetylgalactosamine-tetraacylated)
An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
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Ac4GlcNAl (N-4-pentynoyl-glucosamine-tetraacylated)
An alkyne-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
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Ac4GlcNAz (N-Azidoacetylglucosamine-tetraacylated)
An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
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Ac4ManNAl (N-(4-pentynoyl)-mannosamine-tetraacylated)
An alkyne-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
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Ac4ManNAz (N-Azidoacetylmannosamine-tetraacylated)
An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
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AmdU (5-Azidomethyl-2'-deoxyuridine)
Azidomethyldeoxyuridine (AmdU) is an azide-contained nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain-promoted click reaction.
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BrdU (5-Bromo-2′-deoxyuridine)
BrdU is a synthetic analog of thymidine for studying de novo DNA synthesis and cell proliferation.
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EdU (5-Ethynyl-2'-deoxyuridine)
EdU is a nucleoside that is incorporated into replicated DNA by cellular enzymes. After it, DNA contained in the cells can be developed by click chemistry reaction with fluorescent dye azides to reveal cell proliferation.
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F-ara-EdU (2’-Deoxy-2’-fluoro-5-ethynyluridine)
F-ara-EdU is a synthetic analog of thymidine used to study de novo DNA synthesis and cell proliferation. It is a less cytotoxic alternative for BrdU and EdU.
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HPG (L-Homopropargylglycine)
Noncanonical amino acid analog of methionine with a terminal alkyne moiety for nascent protein synthesis detection.
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VU (5-Vinyl-uridine)
Uridine derivative with a terminal alkene group for monitoring and investigating cell RNA transcription.
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VdU (5-Vinyl-2'-deoxyuridine)
VdU is a synthetic analog of thymidine for studying de novo DNA synthesis and cell proliferation.
Mounting media for microscopy
Fluorescence mounting media for microscopy applications.
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LumiMount DAPI Fluorescence Mounting Medium
An aqueous anti-fade mounting medium with DAPI for coverslipping and imaging fluorescently labeled cell or tissue samples.
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LumiMount Fluorescence Mounting Medium
An aqueous anti-fade mounting medium for coverslipping cells and tissues stained with various fluorescent dyes.
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LumiMount Plus Fluorescence Mounting Medium
An aqueous, high refractive index mounting medium for coverslipping and imaging fluorescently labeled cell or tissue samples.
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(E/Z)-4-Hydroxytamoxifen
(E/Z)-4-Hydroxytamoxifen (4-OHT, afimoxifene) is a selective estrogen receptor (ER) modulator, an active tamoxifen metabolite widely used for inducible genome manipulation.
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Annexin V, His Tag
Recombinant Human Annexin V for producing fluorescent Annexin V conjugates and inhibition of the procoagulant and proinflammatory activities of the apoptotic cells.
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BAPTA AM, calcium chelator
Cell-permeable acetoxymethyl ester (AM) form of BAPTA, a highly selective calcium chelator for cell signaling studies.
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DREADD agonist 21 dihydrochloride
An agonist for selective activation of hM3Dq (excitatory) and hM4Di (inhibitory) DREADDs. A widely used chemogenetic tool for remotely controlling neuronal activity.
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FCCP, ATPase inhibitor
FCCP is a strong uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP production by transporting protons across cellular membranes.
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H-Met-AMC, сalpain substrate
Fluorogenic substrate for methionine aminopeptidase 2 or aminopeptidase N.
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Vacuolin-1
Cell-permeable inhibitor of calcium-dependent lysosomal exocytosis.
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