Cell biology reagents

Cell biology reagents / product groups & items in this category
Dyes and reagents for cell biology: cell markers and indicators, substances for metabolic labeling, inhibitors, etc.

Nuclear stains

Cell-membrane permeant and impermeant DNA dyes for specific staining nuclei in live or fixed cells.
Group tags Nuclei, Flow cytometry, Microscopy, Ribosomes, Cell viability and apoptosis, Nucleoli, Super-resolution imaging

Plasma membrane stains

Lipophilic dyes with different spectral properties for plasma membrane staining and visualization of cell boundaries and morphology.
Group tags Near infrared (NIR) imaging, Cell proliferation, Neuroscience, Flow cytometry, Cell membrane, Microscopy

Organelle stains

Reagents and kits for detecting specific cell organelles and structures in live and fixed cells.
Group tags Near infrared (NIR) imaging, Endoplasmic reticulum, BDP® 650/665, Synaptic vesicles, Membrane potential measurement, Lipid bodies, Mitochondria, Neuroscience, Flow cytometry, TAMRA (TMR, Tetramethylrhodamine), Cell membrane, Golgi apparatus, Microscopy, Ribosomes, Cell viability and apoptosis, Nucleoli, Lysosomes
    • LumiTracker® Lyso Green
    • BDP® TR ceramide
      Fluorescent derivative of sphingosine with emission in the red spectrum region for visualization of the Golgi apparatus in cells.
    • LumiTracker® Mito Orange CM-H2TMRos
      A cationic, orange-fluorescent dye for staining active mitochondria in live cells. CM-H2TMRos is a reduced, nonfluorescent version of the CMTMRos dye that becomes fluorescent when oxidized at the mitochondrial membrane.
    • Bis-ANS, protein conformation probe
      High-affinity fluorescent probe for nonpolar cavities in proteins to monitor the formation of protein aggregates and indicate protein folding and conformational changes.
    • TOR-G4, G-quadruplexes fluorescent probe
      TOR-G4 is a fluorescent probe that allows sensitive distinction of G-quadruplexes RNA based on changes to the fluorescence lifetime of a probe upon nucleic acid binding.
    • Deep-Red Fluorescent Nissl Stain
      Far-red fluorescent Nissl stain for visualization and assessment of neural tissue morphology.
    • LumiTracker® ER Red
      Red fluorescent stain for selective labeling of endoplasmic reticulum (ER) in live cells.
    • LumiTracker® ER Green
      Green fluorescent stain for selective labeling of endoplasmic reticulum (ER) in live cells.
    • LumiTracker® Mito Green FM
      Сell-permeant cationic green-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner.
    • SynaptoProbe® Red
      SynaptoProbe® Red is an analog of FM®4-64, a widely used red fluorescent dye for staining synaptic vesicles and studying synaptic activity in the synapses or neuromuscular junctions.
    • SynaptoProbe® Green
      SynaptoProbe® Green is an analog of FM®1-43, a widely used green fluorescent dye for staining synaptic vesicles and studying synaptic activity in the synapses or neuromuscular junctions.
    • LumiTracker® Mito Red FM
      Сell-permeant, cationic, red-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner.
    • LumiTracker® Mito Orange CMTMRos
      Сell-permeant, cationic, orange-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner. The stain is compatible with aldehyde fixation.
    • LumiTracker® Mito Red CMXRos
      Сell-permeant, cationic, red-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner. The stain is compatible with aldehyde fixation.
    • BDP® TMR ceramide
      Fluorescent derivative of sphingosine with emission in the orange spectrum region for visualization of the Golgi apparatus in cells.
    • LumiTracker® Lyso Red
    • BDP® FL ceramide
      Fluorescent derivative of sphingosine with emission in the green spectrum region for visualization of the Golgi apparatus in cells.
    • LumiTracker® Mito Rhodamine 123
      Rhodamine 123 is a cell-permeant, green-fluorescent dye that stains mitochondria in living cells in a membrane potential-dependent manner.
    • LumiTracker® Mito JC-1
      The cationic carbocyanine dye that is widely used as an indicator of mitochondrial membrane potential to study apoptosis and monitor the health of mitochondria.
    • BDP® 630/650 lipid stain
      Far-red fluorescent dye BDP 630/650 for staining of lipids and and other lipophilic compounds.
    • BDP® 650/665 lipid stain
      Hydrophobic borondipyrromethene dye BDP 650/665 for staining of lipids and lipophilic compounds.
    • TAMRA-2,4-dinitroaniline (TMR-DN)
      TAMRA-2,4-dinitroaniline is a probe for visualizing RNA in living cells.
    • (E,E)-3,5-Bis(phenylethenyl)-BDP® lipid stain
      A non-functionalized 3,5-substituted borondipyrromethene derivative with a Stokes shift of 13 nm and an emission spectrum in the red spectrum range.
    • LumiTracker® Mito TMRE
      Tetramethylrhodamine ethyl ester (TMRE) is an orange-red fluorescent dye for staining active mitochondria and quantitate mitochondrial membrane potential in live cells.
    • BDP® 493/503 lipid stain
      BDP 493/503 is a lipophilic green fluorescent dye for the staining and tracing of cell membranes, lipids, and oils.
    • BDP® 505/515 lipid stain
      BDP 505/515 is a lipid staining dye for cell membranes. It has a high fluorescence quantum yield, and is very photostable.
    • BDP® TR methyl ester
      BDP TR methyl ester is a lipophilic counterstain for GFP. Сell-permeable dye that stains mitochondria and endomembranous organelles, but not plasma membrane.
    • DND-167, blue fluorescent pH indicator
    • LumiTracker® Lyso Blue
      Blue-emitting reagent for labeling and tracking lysosomes and other acidic organelles with low internal pH in live cells. Analog of LysoTracker™ Blue DND-22.

Cell tracing and tracking

Our dyes for anterograde and retrograde tracing of living and fixed cells and cell tracking.
Group tags Near infrared (NIR) imaging, NHS esters, Biotinylation, FAM (Fluorescein), Cell proliferation, Neuroscience, Flow cytometry, Cell membrane, Microscopy, Cell viability and apoptosis

Cell viability indicators

Reagents and ready-to-use kits for studying cell viability and apoptosis by flow cytometry and microscopy.
Group tags Membrane potential measurement, Mitochondria, Cell proliferation, Nuclei, Flow cytometry, Microscopy, Cell viability and apoptosis

ROS indicators

Cell permeant fluorogenic dyes for detection of reactive oxygen species (ROS) in live cells by flow cytometry, microscopy, or fluorimetry.
Group tags ROS sensing, Flow cytometry, Microscopy

Ion and pH indicators

Small fluorogenic molecules for indicating specific ions inside cells in vivo. Cell permeant indicators for Ca-, Fe-ions, pH, and others.
Group tags Membrane potential measurement, Cell proliferation, Neuroscience, Flow cytometry, Microscopy, Cell viability and apoptosis, Lysosomes

Potentiometric probes

Voltage-sensitive dyes for measurement of spatial and temporal fluctuations in membrane potential across the membrane of large cell populations, single cells, and cell organelles.
Group tags Membrane potential measurement, Neuroscience, Flow cytometry, Cell membrane, Microscopy
    • Di-4-ANEPPS, potentiometric probe
      Fast-response potential-sensitive fluorescent probe for imaging functional activity of neurons and heart cells. The dye is quickly internalized by cells and is well-suited for short-term experiments.
    • Di-8-ANEPPS, potentiometric probe
      Fast-response potential-sensitive fluorescent probe for imaging functional activity of neurons and heart cells. The dye has more lipophilic properties than other dyes of the ANEP family, making it well-suited for long-term experiments.
    • RH 237, potentiometric probe
      Fast-response potential-sensitive fluorescent probe for imaging functional activity of mitochondria, neurons, and heart cells.
    • Pluronic® F-127
      A nonionic detergent widely used to solubilize hydrophobic molecules such as cell-permeable AM esters of Fluo-4, Fluorica-8 calcium indicators, and Di-4-ANEPS, Di-8-ANEPS potentiometric probes and facilitate their loading into cells.

Cell type-specific markers

Small-molecule fluorescent markers for different types of cells. A fast and well-permeant to live cells and tissues alternative to antibody labeling.
Group tags Near infrared (NIR) imaging, Endoplasmic reticulum, ICG (Indocyanine Green), Neuroscience, Flow cytometry, Microscopy
    • Indocyanine Green (ICG)
      Water-soluble and pH-insensitive fluorescent dye widely used in imaging and flow cytometry.
    • LumiCell Reticulocyte Stain
      LumiCell Reticulocyte Stain is a ready-to-use Thiazole Orange solution for determining a percentage of reticulocytes in human peripheral blood with microscopy and flow cytometry.
    • LumiCell CDr20 Microglia Stain
      CDr20 is a turn-on fluorescent chemical probe for specific labeling and visualizing microglia in cell cultures and live brains.
    • Deep-Red Fluorescent Nissl Stain
      Far-red fluorescent Nissl stain for visualization and assessment of neural tissue morphology.

Immunofluorescence

Reagents for immunofluorescence applications: fluorescent labeled derivatives of tyramide for signal amplification (TSA), biotin, and streptavidin for Western Blotting, immunoassay, immunochemistry, and in situ hybridization.
Group tags Near infrared (NIR) imaging, AF 488, sulfo-Cyanine5.5, sulfo-Cyanine7, Biotinylation, AF 594, Flow cytometry, sulfo-Cyanine3, Microscopy, Super-resolution imaging, sulfo-Cyanine5, Tyramides, AMCA
    • sulfo-Cyanine5-PEG3-biotin
      Biotin conjugate of the far-red fluorescent sulfo-Cyanine5 dye.
    • sulfo-Cyanine3-PEG3-biotin
      Conjugate of hydrophilic sulfo-Cyanine3 dye with biotin, affinity label for avidin/streptavidin.
    • sulfo-Cyanine3 tyramide
      A tyramide derivative of sulfo-Cyanine3, an orange fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
    • AF 488 streptavidin
      AF 488 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • AF 594 streptavidin
      AF 594 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • sulfo-Cyanine5 streptavidin
      sulfo-Cyanine5 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • sulfo-Cyanine3 streptavidin
      sulfo-Cyanine3 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • sulfo-Cyanine5 tyramide
      A tyramide derivative of sulfo-Cyanine5, a far-red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
    • sulfo-Cyanine7 tyramide
      A tyramide derivative of sulfo-Cyanine7, a near-infrared fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
    • AF 594 tyramide
      A tyramide derivative of AF 594, a red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
    • sulfo-Cyanine5.5 tyramide
      A tyramide derivative of sulfo-Cyanine5.5, a far-red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
    • AF 488 tyramide
      A tyramide derivative of AF 488, a green fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
    • AMCA streptavidin
      AMCA conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • Biotinyl tyramide
      Biotin derivative of tyramide for amplification and subsequent signal detection with a labeled streptavidin conjugate.

Metabolic labeling

Reagents for metabolic in vivo labeling of cells and whole organisms.
Group tags Glycan labeling, Copper-free click chemistry, Cell proliferation, Azides, Flow cytometry, Alkynes, Microscopy, Click chemistry, Cell viability and apoptosis

Mounting media for microscopy

Fluorescence mounting media for microscopy applications.
Group tags Microscopy

Substrates, inhibitors, and activators

Group tags ROS sensing, Mitochondria, Neuroscience, Cell viability and apoptosis, Lysosomes
    • Vacuolin-1
      Cell-permeable inhibitor of calcium-dependent lysosomal exocytosis.
    • Annexin V, His Tag
      Recombinant Human Annexin V for producing fluorescent Annexin V conjugates and inhibition of the procoagulant and proinflammatory activities of the apoptotic cells.
    • DREADD agonist 21 dihydrochloride
      An agonist for selective activation of hM3Dq (excitatory) and hM4Di (inhibitory) DREADDs. A widely used chemogenetic tool for remotely controlling neuronal activity.
    • (E/Z)-4-Hydroxytamoxifen
      (E/Z)-4-Hydroxytamoxifen (4-OHT, afimoxifene) is a selective estrogen receptor (ER) modulator, an active tamoxifen metabolite widely used for inducible genome manipulation.
    • BAPTA AM, calcium chelator
      Cell-permeable acetoxymethyl ester (AM) form of BAPTA, a highly selective calcium chelator for cell signaling studies.
    • FCCP, ATPase inhibitor
      FCCP is a strong uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP production by transporting protons across cellular membranes.
    • H-Met-AMC, сalpain substrate
      Fluorogenic substrate for methionine aminopeptidase 2 or aminopeptidase N.
    • BDP®-aminoacetaldehyde diethyl acetal (BAAA-DA)
      A precursor of BDP®-aminoacetaldehyde (BAAA), a cell-permeable fluorescent substrate for aldehyde dehydrogenase (ALDH), used to identify, isolate, and sort cells with high levels of ALDH activity.
Short link - lumiprobe.com/sh/c/z
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