Cell biology reagents

Cell biology reagents / product groups & items in this category
Dyes and reagents for cell biology: cell markers and indicators, substances for metabolic labeling, inhibitors, etc.

Nuclear stains

Cell-membrane permeant and impermeant DNA dyes for specific staining nuclei in live or fixed cells.
Group tags Microscopy, Ribosomes, Nucleoli, Super-resolution imaging, Mitochondria, Neuroscience, Flow cytometry, Nuclei, Cell viability and apoptosis

Plasma membrane stains

Lipophilic dyes with different spectral properties for plasma membrane staining and visualization of cell boundaries and morphology.
Group tags Near infrared (NIR) imaging, Microscopy, Cell proliferation, Neuroscience, Flow cytometry, Cell membrane

Organelle stains

Reagents and kits for detecting specific cell organelles and structures in live and fixed cells.
Group tags Near infrared (NIR) imaging, Microscopy, TAMRA (TMR, Tetramethylrhodamine), Endoplasmic reticulum, Ribosomes, BDP® 650/665, Synaptic vesicles, Membrane potential measurement, Nucleoli, Lipid bodies, Mitochondria, Neuroscience, Golgi apparatus, Flow cytometry, Cell membrane, Nuclei, Lysosomes, Cell viability and apoptosis, Cytoskeleton
    • (E,E)-3,5-Bis(phenylethenyl)-BDP® lipid stain
      A non-functionalized 3,5-substituted borondipyrromethene derivative with a Stokes shift of 13 nm and an emission spectrum in the red spectrum range.
    • BDP® 493/503 lipid stain
      BDP 493/503 is a lipophilic green fluorescent dye for the staining and tracing of cell membranes, lipids, and oils.
    • BDP® 505/515 lipid stain
      BDP 505/515 is a lipid staining dye for cell membranes. It has a high fluorescence quantum yield, and is very photostable.
    • BDP® 630/650 lipid stain
      Far-red fluorescent dye BDP 630/650 for staining of lipids and and other lipophilic compounds.
    • BDP® 650/665 lipid stain
      Hydrophobic borondipyrromethene dye BDP 650/665 for staining of lipids and lipophilic compounds.
    • Red Fluorescent Nissl Stain
      Red fluorescent Nissl stain for visualizing the morphology of nervous tissue.
    • Deep-Red Fluorescent Nissl Stain
      Far-red fluorescent Nissl stain for visualization and assessment of neural tissue morphology.
    • BDP® FL ceramide
      Fluorescent derivative of sphingosine with emission in the green spectrum region for visualization of the Golgi apparatus in cells.
    • BDP® TMR ceramide
      Fluorescent derivative of sphingosine with emission in the orange spectrum region for visualization of the Golgi apparatus in cells.
    • BDP® TR ceramide
      Fluorescent derivative of sphingosine with emission in the red spectrum region for visualization of the Golgi apparatus in cells.
    • BDP® TR methyl ester
      BDP TR methyl ester is a lipophilic counterstain for GFP. Сell-permeable dye that stains mitochondria and endomembranous organelles, but not plasma membrane.
    • DND-167, blue fluorescent pH indicator
      Blue fluorescent pH-sensitive dye for staining acidic organelles (lysosomes and late endosomes) in living cells.
    • LDS 751, far-red fluorescent nucleic acid stain
      A cell-permeant far-red fluorescent nucleic acid stain used for DNA detection in live and fixed cells.
    • LumiTracker® ER Green
      Green fluorescent stain for selective labeling of endoplasmic reticulum (ER) in live cells.
    • LumiTracker® ER Red
      Red fluorescent stain for selective labeling of endoplasmic reticulum (ER) in live cells.
    • LumiTracker® Lyso Blue
      Blue-emitting reagent for labeling and tracking lysosomes and other acidic organelles with low internal pH in live cells. Analog of LysoTracker™ Blue DND-22.
    • LumiTracker® Lyso Green
      Green-fluorescent dye for visualization of lysosomes in living cells and other cell organelles with a low pH. Analog of LysoTracker™ Green DND-26.
    • LumiTracker® Lyso Red
      Red-fluorescent reagent for labeling and tracking lysosomes and other acidic organelles with low internal pH in live cells. Analog of LysoTracker™ Red DND-99.
    • LumiTracker® Mito JC-1
      The cationic carbocyanine dye that is widely used as an indicator of mitochondrial membrane potential to study apoptosis and monitor the health of mitochondria.
    • LumiTracker® Mito Green FM
      Сell-permeant cationic green-fluorescent dye for staining active mitochondria in living cells.
    • LumiTracker® Mito Orange CM-H2TMRos
      A cationic, orange-fluorescent dye for staining active mitochondria in live cells. CM-H2TMRos is a reduced, nonfluorescent version of the CMTMRos dye that becomes fluorescent when oxidized at the mitochondrial membrane.
    • LumiTracker® Mito Orange CMTMRos
      Сell-permeant, cationic, orange-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner. The stain is compatible with aldehyde fixation.
    • LumiTracker® Mito Red CMXRos
      Сell-permeant, cationic, red-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner. The stain is compatible with aldehyde fixation.
    • LumiTracker® Mito Red FM
      Сell-permeant, cationic, red-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner.
    • LumiTracker® Mito Rhodamine 123
      Rhodamine 123 is a cell-permeant, green-fluorescent dye that stains mitochondria in living cells in a membrane potential-dependent manner.
    • LumiTracker® Mito TMRE
      Tetramethylrhodamine ethyl ester (TMRE) is an orange-red fluorescent dye for staining active mitochondria and quantitate mitochondrial membrane potential in live cells.
    • TOR-G4, G-quadruplexes fluorescent probe
      TOR-G4 is a fluorescent probe that allows sensitive distinction of G-quadruplexes RNA based on changes to the fluorescence lifetime of a probe upon nucleic acid binding.
    • SynaptoProbe® Green
      SynaptoProbe® Green is an analog of FM®1-43, a widely used green fluorescent dye for staining synaptic vesicles and studying synaptic activity in the synapses or neuromuscular junctions.
    • SynaptoProbe® Red
      SynaptoProbe® Red is an analog of FM®4-64, a widely used red fluorescent dye for staining synaptic vesicles and studying synaptic activity in the synapses or neuromuscular junctions.
    • TAMRA-2,4-dinitroaniline (TMR-DN)
      TAMRA-2,4-dinitroaniline is a probe for visualizing RNA in living cells.
    • Bis-ANS, protein conformation probe
      High-affinity fluorescent probe for nonpolar cavities in proteins to monitor the formation of protein aggregates and indicate protein folding and conformational changes.

Cell tracing and tracking

Our dyes for anterograde and retrograde tracing of living and fixed cells and cell tracking.
Group tags Near infrared (NIR) imaging, Microscopy, NHS esters, Biotinylation, FAM (Fluorescein), Cell proliferation, Neuroscience, Flow cytometry, Cell membrane, Nuclei, Cell viability and apoptosis
    • AF 594 biocytin
      AF 594 biocytin is a cell-impermeant fixable polar tracer with red emission that can be used to examine plasma membrane permeability, pinocytosis, transport through gap junctions, and cell-cell or cell-liposome fusion.
    • Lipophilic Tracer Sampler Kit
      The kit containing samplers of eight different lipophilic carbocyanine dyes.
    • Biocytin hydrochloride
      Lysine derivative of biotin for conjugation with avidin or streptavidin, neuroanatomical tracer.
    • DiA, lipophilic tracer
      Wide spectrum fluorescent lipophilic dye for membrane labeling and cell tracing.
    • (5,6)-FAM diacetate NHS ester
      Amine-reactive fluorescein (FAM) derivative, a mixture of 5- and 6-isomers. The reagent becomes brightly green fluorescent once it is hydrolyzed while diffusing into cells. A fluorescent tracer.
    • DiI, lipophilic tracer
      Orange-red fluorescent lipophilic dye for membrane labeling and cell tracing.
    • RAPID DiI, lipophilic tracer
      Orange-red fluorescent lipophilic dye for cell tracing with fast migration into membranes, an analog of FAST DiI™.
    • Lucifer Yellow СН
      A highly sensitive yellow fluorescent dye widely used in neurobiology, cytology, and molecular biology to track cells, study cell-cell interactions, and visualize neurons.
    • CM-DiI, lipophilic tracer
      Orange-red fluorescent lipophilic dye for membrane labeling and cell tracking. Unlike other membrane dyes, CM-DiI persists in cells after their fixation and permeabilization.
    • DiO, lipophilic tracer
      Green fluorescent lipophilic dye for membrane labeling and cell tracing.
    • CytoTracer Blue CMAC
      Non-toxic, cell-permeant blue fluorescent dye for labeling and long-term tracing of living cells.
    • RAPID DiO, lipophilic tracer
      Green fluorescent lipophilic dye for cell tracing with fast migration into membranes, an analog of FAST DiO™.
    • CytoTracer Green CM-BDP®
      Non-toxic, cell-permeant green fluorescent dye for labeling and long-term tracing of living cells.
    • Hydroxystilbamidine
      A fluorescent dye widely used in neuroscience and histochemistry for retrograde neuronal tracing and nucleic acid staining.
    • Neuro-DiO, lipophilic tracer
      Non-aggregating green fluorescent lipophilic dye for membrane labeling and cell tracing.
    • CytoTracer Orange CMTMR
      Non-toxic, cell-permeant orange fluorescent dye for labeling and long-term tracing of living cells.
    • DiD, lipophilic tracer
      Far-red fluorescent lipophilic dye for membrane labeling and cell tracing.
    • DiR, lipophilic tracer
      Near-infrared fluorescent lipophilic dye for membrane labeling and cell tracing.
    • CFDA SE Cell Tracing Kit
      The ready-to-use kit for fluorescent labeling and long-term tracing of cells. CFDA SE is commonly used for measuring and tracking cell divisions.
    • PKH Dyes Diluent
      Diluent for PKH series of membrane labeling dyes.
    • PKH2 Cell Membrane Labeling Kit
      The ready-to-use kit to label cell membranes with green fluorescent PKH2 dye for evaluating cell migration or proliferation.
    • PKH26 Cell Membrane Labeling Kit
      The ready-to-use kit to label cell membranes with red fluorescent PKH26 dye for evaluating cell migration or proliferation.
    • PKH800 Cell Membrane Labeling Kit
      The ready-to-use kit to label cell membranes with near-infrared fluorescent PKH800 dye for evaluating cell migration or proliferation.

Cell viability indicators

Reagents and ready-to-use kits for studying cell viability and apoptosis by flow cytometry and microscopy.
Group tags Microscopy, Membrane potential measurement, Mitochondria, Cell proliferation, Fluorometry, Flow cytometry, Cell viability and apoptosis

ROS indicators

Cell permeant fluorogenic dyes for detection of reactive oxygen species (ROS) in live cells by flow cytometry, microscopy, or fluorimetry.
Group tags Microscopy, ROS sensing, Mitochondria, Flow cytometry, Cell viability and apoptosis

Ion and pH indicators

Small fluorogenic molecules for indicating specific ions inside cells in vivo. Cell permeant indicators for Ca-, Fe-ions, pH, and others.
Group tags Microscopy, Membrane potential measurement, Neuroscience, Flow cytometry, Lysosomes

Potentiometric probes

Voltage-sensitive dyes for measurement of spatial and temporal fluctuations in membrane potential across the membrane of large cell populations, single cells, and cell organelles.
Group tags Microscopy, Membrane potential measurement, Neuroscience, Flow cytometry, Cell membrane
    • Di-4-ANEPPS, potentiometric probe
      Fast-response potential-sensitive fluorescent probe for imaging functional activity of neurons and heart cells. The dye is quickly internalized by cells and is well-suited for short-term experiments.
    • Di-8-ANEPPS, potentiometric probe
      Fast-response potential-sensitive fluorescent probe for imaging functional activity of neurons and heart cells. The dye has more lipophilic properties than other dyes of the ANEP family, making it well-suited for long-term experiments.
    • RH 237, potentiometric probe
      Fast-response potential-sensitive fluorescent probe for imaging functional activity of mitochondria, neurons, and heart cells.
    • Pluronic® F-127
      A nonionic detergent widely used to solubilize hydrophobic molecules such as cell-permeable AM esters of Fluo-4, Fluorica-8 calcium indicators, and Di-4-ANEPS, Di-8-ANEPS potentiometric probes and facilitate their loading into cells.

Cell type-specific markers

Small-molecule fluorescent markers for different types of cells. A fast and well-permeant to live cells and tissues alternative to antibody labeling.
Group tags Near infrared (NIR) imaging, ICG (Indocyanine Green), Microscopy, Endoplasmic reticulum, Neuroscience, Flow cytometry

Immunofluorescence

Reagents for immunofluorescence applications: fluorescent labeled derivatives of tyramide for signal amplification (TSA), biotin, and streptavidin for Western Blotting, immunoassay, immunochemistry, and in situ hybridization.
Group tags Near infrared (NIR) imaging, AF 488, Microscopy, Tyramides, sulfo-Cyanine5.5, sulfo-Cyanine7, Biotinylation, AF 594, Super-resolution imaging, Alkynes, sulfo-Cyanine5, Flow cytometry, AMCA, sulfo-Cyanine3
    • AMCA streptavidin
      AMCA conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • AF 488 streptavidin
      AF 488 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • sulfo-Cyanine3 streptavidin
      sulfo-Cyanine3 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • sulfo-Cyanine5 streptavidin
      sulfo-Cyanine5 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • sulfo-Cyanine3-PEG3-biotin
      Conjugate of hydrophilic sulfo-Cyanine3 dye with biotin, affinity label for avidin/streptavidin.
    • sulfo-Cyanine5-PEG3-biotin
      Biotin conjugate of the far-red fluorescent sulfo-Cyanine5 dye.
    • sulfo-Cyanine3 tyramide
      A tyramide derivative of sulfo-Cyanine3, an orange fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
    • AF 594 streptavidin
      AF 594 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • sulfo-Cyanine5 tyramide
      A tyramide derivative of sulfo-Cyanine5, a far-red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
    • sulfo-Cyanine7 tyramide
      A tyramide derivative of sulfo-Cyanine7, a near-infrared fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
    • AF 594 tyramide
      A tyramide derivative of AF 594, a red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
    • sulfo-Cyanine5.5 tyramide
      A tyramide derivative of sulfo-Cyanine5.5, a far-red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
    • AF 488 tyramide
      A tyramide derivative of AF 488, a green fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
    • Biotinyl tyramide
      Biotin derivative of tyramide for amplification and subsequent signal detection with a labeled streptavidin conjugate.
    • Alkyne tyramide
      A bifunctional molecule containing tyramide and alkyne residues for clickable ascorbate peroxidase 2 (APEX2) protein labeling.

Metabolic labeling

Reagents for metabolic in vivo labeling of cells and whole organisms.
Group tags Glycan labeling, Microscopy, Copper-free click chemistry, Alkynes, Cell proliferation, Click chemistry, Flow cytometry, Azides, Cell viability and apoptosis

Mounting media for microscopy

Fluorescence mounting media for microscopy applications.
Group tags Microscopy

Substrates, inhibitors, and activators

Group tags AF 488, Microscopy, Protein labeling, ROS sensing, Mitochondria, Cell proliferation, Neuroscience, Flow cytometry, Lysosomes, Cell viability and apoptosis
    • BAPTA AM, calcium chelator
      Cell-permeable acetoxymethyl ester (AM) form of BAPTA, a highly selective calcium chelator for cell signaling studies.
    • BDP®-aminoacetaldehyde diethyl acetal (BAAA-DA)
      A precursor of BDP®-aminoacetaldehyde (BAAA), a cell-permeable fluorescent substrate for aldehyde dehydrogenase (ALDH), used to identify, isolate, and sort cells with high levels of ALDH activity.
    • DREADD agonist 21 dihydrochloride
      An agonist for selective activation of hM3Dq (excitatory) and hM4Di (inhibitory) DREADDs. A widely used chemogenetic tool for remotely controlling neuronal activity.
    • (E/Z)-4-Hydroxytamoxifen
      (E/Z)-4-Hydroxytamoxifen (4-OHT, afimoxifene) is a selective estrogen receptor (ER) modulator, an active tamoxifen metabolite widely used for inducible genome manipulation.
    • H-Met-AMC, сalpain substrate
      Fluorogenic substrate for methionine aminopeptidase 2 or aminopeptidase N.
    • 1-Methoxy PMS, electron mediator
      A stable, water-soluble electron-transfer mediator used in biochemical assays involving NAD(P)H-dependent dehydrogenases.
    • Vacuolin-1
      Cell-permeable inhibitor of calcium-dependent lysosomal exocytosis.
    • Annexin V, His Tag
      Recombinant Human Annexin V for producing fluorescent Annexin V conjugates and inhibition of the procoagulant and proinflammatory activities of the apoptotic cells.
    • FCCP, ATPase inhibitor
      FCCP is a strong uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP production by transporting protons across cellular membranes.
    • AF 488 HTag ligand
      A green fluorescent substrate for genetically engineered bacterial haloalkane dehalogenase used for selective labeling HaloTag® fusion proteins.

Labeled proteins

Ready-to-use protein conjugates with organic fluorophores designed for visualization, tracking, and quantitative analysis in systems.
Group tags Near infrared (NIR) imaging, AF 488, AF 647, Microscopy, sulfo-Cyanine7.5, AF 594, Super-resolution imaging, sulfo-Cyanine5, Neuroscience, Flow cytometry, AMCA, sulfo-Cyanine3, Cell viability and apoptosis
    • AMCA streptavidin
      AMCA conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • AF 488 streptavidin
      AF 488 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • sulfo-Cyanine3 streptavidin
      sulfo-Cyanine3 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • sulfo-Cyanine5 streptavidin
      sulfo-Cyanine5 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • Annexin V, AF 488 conjugate
      Annexin V AF 488 conjugate for detection of apoptotic cells by flow cytometry and fluorescence microscopy.
    • AF 594 streptavidin
      AF 594 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
    • Annexin V, AF 647 conjugate
      Annexin V AF 647 conjugate for detection of apoptotic cells by flow cytometry and fluorescence microscopy.
    • Bovine Serum Albumin (BSA), AF 488 conjugate
      A ready-to-use fluorescent conjugate of bovine serum albumin (BSA) with the bright and photostable green fluorophore AF 488.
    • Bovine Serum Albumin (BSA), AF 647 conjugate
      A ready-to-use fluorescent conjugate of Bovine Serum Albumin (BSA) with the bright and photostable far-red dye AF 647, utilized for a wide range of applications in cell biology, neurobiology, immunology, and biochemistry.
    • Bovine Serum Albumin (BSA), sulfo-Cyanine7.5 conjugate
      A ready-to-use fluorescent conjugate of Bovine Serum Albumin (BSA) with the bright and exceptionally photostable dye sulfo-Cyanine7.5 emitting in the near-infrared (NIR) region.
Short link - lumiprobe.com/sh/c/z
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