VdU (5-Vinyl-2'-deoxyuridine)

Cell proliferation Copper-free click chemistry
Cat. # Quantity Price Lead time
B2540 5 mg
– 
in stock
D2540 25 mg
$225
 in stock
F2540 100 mg
$785
 in stock
Sample request
Found better price? Let us know and we will propose the way forward!

VdU (5-Vinyl-2’-deoxyuridine) is a synthetic analog of thymidine that can be used to study de novo DNA synthesis and cell proliferation. It is a potential replacement for BrdU (5-Bromo-2’-deoxyuridine) or EdU (5-Ethynyl-2’-deoxyuridine).

VdU incorporates into replicating DNA during the S-phase of the cell cycle instead of natural thymidine. The resulting vinyl-functionalized DNA can be detected by introducing either a biotin or fluorescent dye group via a cooper-free alkene-tetrazine reaction (also known as Inverse electron demand Diels-Alder ligation or IEDDA) and used for subsequent DNA purification or cell imaging tasks.

VdU (5-Vinyl-2'-deoxyuridine), F2540
VdU (5-Vinyl-2'-deoxyuridine), F2540
VdU (5-Vinyl-2'-deoxyuridine), F2540
Structure of VdU (5-Vinyl-2'-deoxyuridine)
Download in
ChemDraw format

Customers also purchased with this product

Pyrene azide 2

Pyrene azide with longer triethyleneglycol (PEG3) linker for click chemistry.

Cyanine5.5 tetrazine

A compound containing Cyanine5.5 fluorophore, a far red emitting dye, and tetrazine fragment for the conjugation with trans-cyclooctenes / cyclopropenes via TCO ligation.

sulfo-Cyanine7 maleimide

Water-soluble near-infrared dye maleimide for the labeling of proteins and peptides.

General properties

Appearance: yellowish solid
Molecular weight: 254.24
CAS number: 55520-67-7
Molecular formula: C11H14N2O5
Solubility: in DMSO
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
Short link - lumiprobe.com/sh/p/a8
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.