VdU (5-Vinyl-2'-deoxyuridine)

Cat. # Quantity Price Lead time
B2540 5 mg –   in stock
D2540 25 mg $225 in stock
F2540 100 mg $785 in stock
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VdU (5-Vinyl-2’-deoxyuridine) is a synthetic analog of thymidine that can be used to study de novo DNA synthesis and cell proliferation. It is a potential replacement for BrdU (5-Bromo-2’-deoxyuridine) or EdU (5-Ethynyl-2’-deoxyuridine).

VdU incorporates into replicating DNA during the S-phase of the cell cycle instead of natural thymidine. The resulting vinyl-functionalized DNA can be detected by introducing either a biotin or fluorescent dye group via a cooper-free alkene-tetrazine reaction (also known as Inverse electron demand Diels-Alder ligation or IEDDA) and used for subsequent DNA purification or cell imaging tasks.

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General properties

Appearance: yellowish solid
Molecular weight: 254.24
CAS number: 55520-67-7
Molecular formula: C11H14N2O5
Solubility: in DMSO
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
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