TCO-PEG4-NHS ester (axial isomer)

Cat. # Quantity Price Lead time
3056-10mg 10 mg $145 in stock
3056-25mg 25 mg $225 in stock
3056-100mg 100 mg $550 in stock
Found better price? Let us know and we will propose the way forward!

TCO-PEG4-NHS ester is a bifunctional linker with trans-cyclooctene (TCO) and NHS ester groups flanking PEG4 (tetraethylene glycol).

The PEG spacer increases solubility in aqueous media and provides a long and flexible connection that minimizes steric hindrance involved with ligation.

The amine-reactive N-hydroxysuccinimide residue provides easy attachment to almost any primary or secondary amine group, such as protein, peptide, or small molecule amine.

Trans-cyclooctene readily reacts with tetrazines via inverse electron-demand Diels-Alder cycloaddition (IEDDA). TCO-Tetrazine ligation possesses ultrafast kinetics, selectivity, and long-term aqueous stability, which is important in low-concentration applications such as protein-protein conjugations, etc.

Customers also purchased with this product

AF 555 azide

Azide derivative of yellow fluorescent dye AF 555 for сlick сhemistry.

AF 488 streptavidin

AF 488 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.

BDP FL carboxylic acid

Borondipyrromethene dye for fluorescein (FAM) channel, free unactivated carboxylic acid useful as a negative control, and for the calibration.
Add this product to your cart and
get free express delivery

General properties

Appearance: colorless syrup
Molecular weight: 514.57
CAS number: 1621096-79-4
Molecular formula: C24H38N2O10
Solubility: DMSO, DMF, THF, Acetonitrile, Dichloromethane
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.