DBCO-PEG6-NHS ester

Cat. # Quantity Price Lead time
3664-10mg 10 mg –   in stock
3664-50mg 50 mg $247 in stock
3664-100mg 100 mg $449 in stock
3664-1g 1 g $3490 5 days
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DBCO-PEG6-NHS ester is a bifunctional linker with dibenzocyclooctyne (DBCO) and NHS ester groups flanking PEG6 (hexaethylene glycol). The PEG spacer increases solubility in aqueous media and provides a long and flexible connection that minimizes steric hindrance involved with ligation.

Dibenzocyclooctyne readily reacts with azides via copper-free click chemistry reaction (strain-promoted alkyne azide cycloaddition, SPAAC). DBCO is one of the most reactive cycloalkynes that does not react with tetrazines.

The amine-reactive N-hydroxysuccinimide residue provides easy attachment to almost any primary or secondary amine group, such as protein, peptide, or small molecule amine.

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General properties

Appearance: yellow to slightly orange oil
Molecular weight: 751.82
Molecular formula: C39H49N3O12
Solubility: DMSO, DMF, DCM, THF, Chloroform
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
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