Alkyne-PEG3-NHS ester

Cat. # Quantity Price Lead time
2298-1g 1 g $490.00 in stock
2298-5g 5 g $980.00 10 days
2298-25g 25 g please inquire 21 days

Alkyne-PEG3-NHS ester is a bifunctional molecule containing NHS ester and alkyne functional groups. NHS ester group is used for the labeling of amine groups, like lysine and N-terminal NH2, in proteins and peptides. And terminal alkyne group is useful for copper catalyzed Click chemistry (CuAAc) or Sonogashira coupling.

PEG3 linker is hydrophilic, and provides a good separation between the parts of the conjugate.

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Hexynoic acid STP ester

Alkyne activated ester for the modification of amine groups. STP ester group is an excellent alternative to NHS ester functionality.


Alkyne PEG3 amine is a medium length heterobifunctional linker for the conjugation.

General properties

Appearance: colorless to yellowish oil
Molecular weight: 357.36
CAS number: 1428629-70-2
Molecular formula: C16H23NO8
IUPAC name: 2,5-Dioxo-1-pyrrolidinyl 3-(2-{2-[2-(2-propynyloxy)ethoxy]ethoxy}ethoxy)propionate
Solubility: good in water, many polar organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications
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