Sulfo-Cyanine5.5 azide

Cat. # Quantity Price Lead time
A7330 1 mg $110.00 5 days
B7330 5 mg $290.00 in stock
C7330 10 mg $470.00 in stock
D7330 25 mg $690.00 in stock
E7330 50 mg $1270.00 in stock
F7330 100 mg $1990.00 in stock

Sulfo-Cyanine5.5 is a water-soluble, hydrophilic fluorophore which possesses emission in far red area of the spectrum, an analog of Cy5.5®. As other cyanine dyes, sulfo-Cyanine5.5 has an outstanding molar extinction coefficient which gives rise to its bright fluorescence.

The molecule contains four sulfo groups that provide hydrophilicity and negative charge to the fluorophore - this minimizes non-specific binding.

The azide group of sulfo-Cyanine5.5 azide can be conjugated with terminal alkynes in the presence of copper(I) catalyst, or with cycloalkynes in copper free strain promoted reaction.

Sulfo-Cyanine5.5 absorption and emission spectra

Sulfo-Cyanine5.5 absorption and emission spectra

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General properties

Appearance: dark colored solid
Mass spec M+ increment: 984.2
Molecular weight: 1099.41
Molecular formula: C43H45K3N6O13S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 235000
Emission maximum, nm: 691
CF260: 0.09
CF280: 0.11

Product citations

  1. Erel-Akbaba, G.; Carvalho, L.A.; Tian, T.; Zinter, M.; Akbaba, H.; Obeid, P.J.; Chiocca, E.A.; Weissleder, R.; Kantarci, A.G.; Tannous, B.A. Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy. ACS Nano, 2019, 13(4), 4028–4040. doi: 10.1021/acsnano.8b08177
  2. Gu, W.; Bobrin, V.A.; Chen, S.-P.R.; Wang, Z.; Schoning, J.P.; Gu, Y.; Chen, W.; Chen, M.; Jia, Z.; Monteiro, M.J. Biodistribution of PNIPAM-Coated Nanostructures Synthesized by the TDMT Method. Biomacromolecules, 2019, 20(2), 625–634. doi: 10.1021/acs.biomac.8b01196
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