Sulfo-Cyanine7 NHS ester

Cat. # Quantity Price Lead time
15320 1 mg $110.00 in stock
25320 5 mg $290.00 in stock
45320 25 mg $690.00 in stock
55320 50 mg $1270.00 in stock
65320 100 mg $1990.00 in stock
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Water soluble near infrared dye sulfo-Cyanine7, an amine-reactive succinimide ester.

Sulfo-Cyanine7 is an improved analog of Cy7® fluorophore with quantum yield improved by 20%, and higher photostability. This fluorescent dye is especially useful for NIR imaging.

Near infrared fluorescent imaging takes advantage of transparency of biological tissues at particular range of wavelengths. The method is non-destructive, and allows to monitor distribution of various labeled molecules in live organisms.

Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and drug design related experiments.

This reagent has high water solubility, and is especially useful for the labeling of delicate proteins, and proteins prone to denaturation. Non-sulfonated Cyanine7 NHS ester soluble in organic phase is also available.

Sulfo-Cyanine7 absorbance and emission spectra

Sulfo-Cyanine7 absorbance and emission spectra

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General properties

Appearance: dark green powder
Molecular weight: 827.94
Molecular formula: C41H46N3NaO10S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download

Spectral properties

Excitation maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
CF260: 0.04
CF280: 0.04

Product citations

  1. Bhatnagar, S.; Verma, K.D.; Hu, Y.; Khera, E.; Priluck, A.; Smith, D.E.; Thurber, G.M. Oral Administration and Detection of a Near-Infrared Molecular Imaging Agent in an Orthotopic Mouse Model for Breast Cancer Screening. Molecular Pharmaceutics, 2018, 15(5), 1746–1754. doi: 10.1021/acs.molpharmaceut.7b00994
  2. Gaspar, I.; Hövelmann, F.; Chamiolo, J.; Ephrussi, A.; Seitz, O. Quantitative mRNA Imaging with Dual Channel qFIT Probes to Monitor Distribution and Degree of Hybridization. ACS Chemical Biology, 2018, 13(3), 742–749. doi: 10.1021/acschembio.7b01007
  3. Liu, Z.; Wang, S.; Li, W.; Tian, Y. Bioimaging and Biosensing of Ferrous Ion in Neurons and HepG2 Cells Upon Oxidative Stress. Analytical Chemistry, 2018, 90(4), 2816–2825. doi: 10.1021/acs.analchem.7b04934
  4. Das, S.; Haedicke, K.; Grimm, J. Cerenkov-activated sticky tag for in vivo fluorescence imaging. Journal of Nuclear Medicine, 2018, 59(1), 58–65. doi: 10.2967/jnumed.117.198549
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