Sulfo-Cyanine7 NHS ester

Cat. # Quantity Price Lead time
15320 1 mg $110.00 in stock
25320 5 mg $290.00 in stock
45320 25 mg $690.00 7 days
55320 50 mg $1270.00 in stock
65320 100 mg $1990.00 in stock

Water soluble near infrared dye sulfo-Cyanine7, an amine-reactive succinimide ester.

Sulfo-Cyanine7 is an improved analog of Cy7® fluorophore with quantum yield improved by 20%, and higher photostability. This fluorescent dye is especially useful for NIR imaging.

Near infrared fluorescent imaging takes advantage of transparency of biological tissues at particular range of wavelengths. The method is non-destructive, and allows to monitor distribution of various labeled molecules in live organisms.

Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and drug design related experiments.

This reagent has high water solubility, and is especially useful for the labeling of delicate proteins, and proteins prone to denaturation. Non-sulfonated Cyanine7 NHS ester soluble in organic phase is also available.

Sulfo-Cyanine7 absorbance and emission spectra

Sulfo-Cyanine7 absorbance and emission spectra

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Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

FAM azide, 5-isomer

FAM (fluorescein) azide for Click chemistry, pure 5-isomer.

General properties

Appearance: dark green powder
Molecular weight: 844.05
CAS number: 1603861-95-5 (potassium salt); 1604244-45-2 (inner salt)
Molecular formula: C41H46N3KO10S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
CF260: 0.04
CF280: 0.04

Product citations

  1. Molotkov, A.; Bhatt, N.; Doubrovin, M.; Castrillon, J.; Massa, C.; Gerber, A.; D'Armiento, J.; Goldklang, M.; Mintz, A. Multimodality molecular imaging of the alveolar-capillary barrier in lung disease using albumin based optical and PET tracers. Molecular Biomedicine, in press. doi: 10.1186/s43556-020-00020-1
  2. González, L.F.; Acuña, E.; Arellano, G.; Morales, P.; Sotomayor, P.; Oyarzun-Ampuero, F.; Naves, R. Intranasal delivery of interferon-β-loaded nanoparticles induces control of neuroinflammation in a preclinical model of multiple sclerosis: A promising simple, effective, non-invasive, and low-cost therapy. Journal of Controlled Release, in press. doi: 10.1016/j.jconrel.2020.11.019
  3. Trac, N.; Chen, L.-Y.; Zhang, A.; Liao, C.-P.; Poon, C.; Wang, J.; Ando, Y.; Joo, J.; Garri, C.; Shen, K.; Kani, K.; Gross, M.E.; Chung, E.J. CCR2-targeted micelles for anti-cancer peptide delivery and immune stimulation. Journal of Controlled Release, in press. doi: 10.1016/j.jconrel.2020.09.054
  4. Huayamares, S.G.; Song, J.Y.; Huang, A.; Crowl, S.R.; Groer, C.E.; Forrest, M.L.; Berkland, C.J. Constructing a Biomaterial to Simulate Extracellular Drug Transport in Solid Tumors. Macromolecular Bioscience, 2020, 20(12), 2000251. doi: 10.1002/mabi.202000251
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