sulfo-Cyanine7 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 15320 | 1 mg | $125 | in stock | |
| 25320 | 5 mg | $325 | in stock | |
| 45320 | 25 mg |
$850
|
in stock | |
| 55320 | 50 mg |
$1490
|
in stock | |
| 65320 | 100 mg |
$1990
|
in stock |
Water-soluble near-infrared dye sulfo-Cyanine7, an amine-reactive succinimide ester.
sulfo-Cyanine7 is an improved analog of Cy7® fluorophore with quantum yield improved by 20%, and higher photostability. This fluorescent dye is especially useful for NIR imaging.
Near-infrared fluorescent imaging takes advantage of the transparency of biological tissues at a particular range of wavelengths. The method is non-destructive and allows to monitor of the distribution of various labeled molecules in live organisms.
sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye-labeled molecules can be subsequently used for various research and drug design-related experiments.
This reagent has high water solubility and is especially useful for labeling delicate proteins and proteins prone to denaturation. Non-sulfonated Cyanine7 NHS ester soluble in the organic phase is also available.
sulfo-Cyanine7 absorbance and emission spectra
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| Appearance: | dark green powder |
| Molecular weight: | 844.05 |
| CAS number: | 1603861-95-5 (potassium salt); 1604244-45-2 (inner salt); 477908-53-5 (N-Ethyl) |
| Molecular formula: | C41H46N3KO10S2 |
| Solubility: | good in water, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 750 |
| ε, L⋅mol−1⋅cm−1: | 240600 |
| Emission maximum, nm: | 773 |
| Fluorescence quantum yield: | 0.24 |
| CF260: | 0.04 |
| CF280: | 0.04 |
Product citations
- Zeng, Z.; Tan, R.; Chen, S.; Chen, H.; Liu, Z.; Liu, L.; Li, M.; Chen, Y. Di-PEGylated insulin: A long-acting insulin conjugate with superior safety in reducing hypoglycemic events. Acta Pharmaceutica Sinica B, 2024. doi: 10.1016/j.apsb.2024.02.022
- Stinson, B.M.; Carney, S.M.; Walter, J.C.; Loparo, J.J. Structural role for DNA Ligase IV in promoting the fidelity of non-homologous end joining. Nature Communications, 2024, 15, 1250. doi: 10.1038/s41467-024-45553-z
- Barberio, A. E.; Smith, S. G.; Pires, I. S.; Iyer, S.; Reinhardt, F.; Melo, M. B.; Suh, H.; Weinberg, R. A.; Irvine, D. J.; Hammond, P. T. Layer-by-Layer Interleukin-12 Nanoparticles Drive a Safe and Effective Response in Ovarian Tumors. Bioengineering & Translational Medicine, 2023, 8(2), e10453. doi: 10.1002/btm2.10453
- Sandberg, E.; Piguet, J.; Kostiv, U.; Baryshnikov, G.; Liu, H.; Widengren, J. Photoisomerization of Heptamethine Cyanine Dyes Results in Red-Emissive Species: Implications for Near-IR, Single-Molecule, and Super-Resolution Fluorescence Spectroscopy and Imaging. J Phys Chem B, 2023, 127(14), 3208–3222. doi: 10.1021/acs.jpcb.2c08016
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