Sulfo-Cyanine7 NHS ester

Cat. # Quantity Price Lead time
15320 1 mg $110.00 in stock
25320 5 mg $290.00 in stock
45320 25 mg $690.00 in stock
55320 50 mg $1270.00 in stock
65320 100 mg $1990.00 in stock

Water soluble near infrared dye sulfo-Cyanine7, an amine-reactive succinimide ester.

Sulfo-Cyanine7 is an improved analog of Cy7® fluorophore with quantum yield improved by 20%, and higher photostability. This fluorescent dye is especially useful for NIR imaging.

Near infrared fluorescent imaging takes advantage of transparency of biological tissues at particular range of wavelengths. The method is non-destructive, and allows to monitor distribution of various labeled molecules in live organisms.

Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and drug design related experiments.

This reagent has high water solubility, and is especially useful for the labeling of delicate proteins, and proteins prone to denaturation. Non-sulfonated Cyanine7 NHS ester soluble in organic phase is also available.

Sulfo-Cyanine7 absorbance and emission spectra

Sulfo-Cyanine7 absorbance and emission spectra

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Cyanine5 hydrazide

Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.

Sulfo-Cyanine5.5 amine

Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.

General properties

Appearance: dark green powder
Molecular weight: 844.05
CAS number: 1603861-95-5 (potassium salt); 1604244-45-2 (inner salt); 477908-53-5 (N-Ethyl)
Molecular formula: C41H46N3KO10S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
CF260: 0.04
CF280: 0.04

Product citations

  1. Trac, N.; Chen, L.-Y.; Zhang, A.; Liao, C.-P.; Poon, C.; Wang, J.; Ando, Y.; Joo, J.; Garri, C.; Shen, K.; Kani, K.; Gross, M.E.; Chung, E.J. CCR2-targeted micelles for anti-cancer peptide delivery and immune stimulation. Journal of Controlled Release, 2021, 329, 614–623. doi: 10.1016/j.jconrel.2020.09.054
  2. González, L.F.; Acuña, E.; Arellano, G.; Morales, P.; Sotomayor, P.; Oyarzun-Ampuero, F.; Naves, R. Intranasal delivery of interferon-β-loaded nanoparticles induces control of neuroinflammation in a preclinical model of multiple sclerosis: A promising simple, effective, non-invasive, and low-cost therapy. Journal of Controlled Release, 2021, 331, 443–459. doi: 10.1016/j.jconrel.2020.11.019
  3. Shapoval, O.; Oleksa, V.; Šlouf, M.; Lobaz, V.; Trhlíková, O.; Filipová, M.; Janoušková, O.; Engstová, H.; Pankrác, J.; Modrý, A.; Herynek, V.; Ježek, P.; Šefc, L.; Horák, D. Colloidally Stable P(DMA-AGME)-Ale-Coated Gd(Tb)F3:Tb3+(Gd3+),Yb3+,Nd3+ Nanoparticles as a Multimodal Contrast Agent for Down- and Upconversion Luminescence, Magnetic. Nanomaterials, 2021, 11(1), 230. doi: 10.3390/nano11010230
  4. Molotkov, A.; Bhatt, N.; Doubrovin, M.; Castrillon, J.; Massa, C.; Gerber, A.; D'Armiento, J.; Goldklang, M.; Mintz, A. Multimodality molecular imaging of the alveolar-capillary barrier in lung disease using albumin based optical and PET tracers. Molecular Biomedicine, 2020, 1(1), 17. doi: 10.1186/s43556-020-00020-1
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