Cyanine7 azide

Cat. # Quantity Price Lead time
15030 100 uL, 10 mM/DMSO –   in stock
35030 500 uL, 10 mM/DMSO $199 in stock
45030 1 mL, 10 mM/DMSO $495 in stock
A5030 1 mg –   in stock
B5030 5 mg $199 in stock
C5030 10 mg $297 in stock
D5030 25 mg $495 in stock
E5030 50 mg $895 in stock
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Cyanine7 azide is a near-infrared fluorescent dye azide for click chemistry labeling, an analog of Cy7® azide.

This product can be used for the incorporation of Cyanine7 into various alkynylated biomolecules via click chemistry. Post-synthetic modification of oligonucleotides is also possible with this azide.

Cyclohexane-bridged polymethyne chain allows for 20% increase in quantum yield (compared to parent non-bridged structure).

Absorbance and emission spectra of Cyanine7

Absorbance and emission spectra of Cyanine7

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General properties

Appearance: green powder / solution
Molecular weight: 667.33
CAS number: 1557149-65-1 (chloride), 1557397-59-7
Molecular formula: C40H51ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

Product citations

  1. Shen, W.; You, T.; Xu, W.; Xie, Y.; Wang, Y.; Cui, M. Rapid and Widespread Distribution of Intranasal Small Extracellular Vesicles Derived from Mesenchymal Stem Cells throughout the Brain Potentially via the Perivascular Pathway. Pharmaceutics, 2023, 15(11), 2578. doi: 10.3390/pharmaceutics15112578
  2. Zeng, Y.; Shen, Y.; Wu, S.; Cai, L.; Wang, Z.; Cai, K.; Shen, J.; Hii Ru Yie, K.; Zhang, H.; Xu, L.; Liu, J. Bone-Targeting PLGA Derived Lipid Drug Delivery System Ameliorates Bone Loss in Osteoporotic Ovariectomized Rats. Materials & Design, 2022, 221, 110967. doi: 10.1016/j.matdes.2022.110967
  3. Roberts, S.; Khera, E.; Choi, C.; Navaratna, T.; Grimm, J.; Thurber, G.M.; Reiner, T. Optoacoustic imaging of Glucagon-like Peptide 1 Receptor with a near-infrared exendin-4 analog. Journal of Nuclear Medicine, 2021, 62(6), 839–848. doi: 10.2967/jnumed.120.252262
  4. Thauvin, C.; Maudens, P.; Allémann, E. Microwave-assisted synthesis of self-assembling bi-functionalizable amphiphilic diblock copolymers. Journal of Drug Delivery Science and Technology, 2021, 61, 102255. doi: 10.1016/j.jddst.2020.102255
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