Cyanine7 azide

Cyanine7 Azides Near infrared (NIR) imaging
Cat. # Quantity Price Lead time
15030 100 uL, 10 mM/DMSO $110.00 in stock
35030 500 uL, 10 mM/DMSO $210.00 in stock
45030 1 mL, 10 mM/DMSO $410.00 5 days
A5030 1 mg $110.00 in stock
B5030 5 mg $210.00 in stock
C5030 10 mg $310.00 in stock
D5030 25 mg $410.00 in stock
E5030 50 mg $695.00 in stock
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Cyanine7 azide is a near-infrared fluorescent dye azide for Click Chemistry labeling, an analog of Cy7® azide.

This product can be used for the incorporation of Cyanine7 into various alkynylated biomolecules via Click Chemistry. Post-synthetic modification of oligonucleotides is also possible with this azide.

Cyclohexane-bridged polymethyne chain allows for 20% increase in quantum yield (compared to parent non-bridged structure).

Cyanine7 azide, azide stock solution for click chemistry (10 mM in DMSO), 15030
Cyanine7 azide, azide stock solution for click chemistry (10 mM in DMSO), 15030
Cyanine7 azide, azide stock solution for click chemistry (10 mM in DMSO), 15030
Cyanine7 azide, D5030
Cyanine7 azide, D5030
Cyanine7 azide, D5030
Cyanine7 azide structure
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Cyanine7 absorbance and emission spectra

Cyanine7 absorbance and emission spectra

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Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

Sulfo-Cyanine7 amine

Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.

General properties

Appearance: green powder / solution
Molecular weight: 667.33
CAS number: 1557149-65-1 (chloride), 1557397-59-7
Molecular formula: C40H51ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

Product citations

  1. Meka, R.R.; Venkatesha, S.H.; Moudgil, K.D. Peptide-directed liposomal delivery improves the therapeutic index of an immunomodulatory cytokine in controlling autoimmune arthritis. Journal of Controlled Release, 2018, 286, 279–288. doi: 10.1016/j.jconrel.2018.08.007
  2. Lyu, Z.; Kang, L.; Buuh, Z.Y.; Jiang, D.; McGuth, J.C.; Du, J.; Wissler, H.L.; Cai, W.; Wang, R.E. A Switchable Site-Specific Antibody Conjugate. ACS Chemical Biology, 2018, 13(4), 958–964. doi: 10.1021/acschembio.8b00107
  3. Maudens, P.; Seemayer, C.A.; Thauvin, C.; Gabay, C.; Jordan, O.; Allémann, E. Nanocrystal-Polymer Particles: Extended Delivery Carriers for Osteoarthritis Treatment. Small, 2018, 14(8), 1703108. doi: 10.1002/smll.201703108
  4. Morton, S.W.; Zhao, X.; Quadir, M.A.; Hammond, P.T. FRET-enabled biological characterization of polymeric micelles. Biomaterials, 2014, 35(11), 3489-3496. doi: 10.1016/j.biomaterials.2014.01.027
Cy® is a trademark of GE Healthcare.
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