Cyanine7 azide
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 15030 | 100 uL, 10 mM/DMSO | $110.00 | in stock | |
| 35030 | 500 uL, 10 mM/DMSO | $210.00 | in stock | |
| 45030 | 1 mL, 10 mM/DMSO |
$410.00
|
in stock | |
| A5030 | 1 mg | $110.00 | in stock | |
| B5030 | 5 mg | $210.00 | in stock | |
| C5030 | 10 mg | $310.00 | in stock | |
| D5030 | 25 mg |
$410.00
|
in stock | |
| E5030 | 50 mg |
$695.00
|
in stock |
Cyanine7 azide is a near-infrared fluorescent dye azide for Click Chemistry labeling, an analog of Cy7® azide.
This product can be used for the incorporation of Cyanine7 into various alkynylated biomolecules via Click Chemistry. Post-synthetic modification of oligonucleotides is also possible with this azide.
Cyclohexane-bridged polymethyne chain allows for 20% increase in quantum yield (compared to parent non-bridged structure).
Cyanine7 absorbance and emission spectra
Recommended protocol
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Solid support for the synthesis of 3'-modified oligonucleotides with alkyne group for Click Chemistry.General properties
| Appearance: | green powder / solution |
| Molecular weight: | 667.33 |
| CAS number: | 1557149-65-1 (chloride), 1557397-59-7 |
| Molecular formula: | C40H51ClN6O |
| Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation maximum, nm: | 750 |
| ε, L⋅mol−1⋅cm−1: | 199000 |
| Emission maximum, nm: | 773 |
| Fluorescence quantum yield: | 0.3 |
| CF260: | 0.022 |
| CF280: | 0.029 |
Product citations
- Meka, R.R.; Venkatesha, S.H.; Moudgil, K.D. Peptide-directed liposomal delivery improves the therapeutic index of an immunomodulatory cytokine in controlling autoimmune arthritis. Journal of Controlled Release, 2018, 286, 279–288. doi: 10.1016/j.jconrel.2018.08.007
- Lyu, Z.; Kang, L.; Buuh, Z.Y.; Jiang, D.; McGuth, J.C.; Du, J.; Wissler, H.L.; Cai, W.; Wang, R.E. A Switchable Site-Specific Antibody Conjugate. ACS Chemical Biology, 2018, 13(4), 958–964. doi: 10.1021/acschembio.8b00107
- Maudens, P.; Seemayer, C.A.; Thauvin, C.; Gabay, C.; Jordan, O.; Allémann, E. Nanocrystal-Polymer Particles: Extended Delivery Carriers for Osteoarthritis Treatment. Small, 2018, 14(8), 1703108. doi: 10.1002/smll.201703108
- Morton, S.W.; Zhao, X.; Quadir, M.A.; Hammond, P.T. FRET-enabled biological characterization of polymeric micelles. Biomaterials, 2014, 35(11), 3489-3496. doi: 10.1016/j.biomaterials.2014.01.027
Cy® is a trademark of GE Healthcare.
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