Cyanine7 azide

Cat. # Quantity Price Lead time
15030 100 uL, 10 mM/DMSO $110.00 in stock
35030 500 uL, 10 mM/DMSO $210.00 in stock
45030 1 mL, 10 mM/DMSO $410.00 in stock
A5030 1 mg $110.00 in stock
B5030 5 mg $210.00 in stock
C5030 10 mg $310.00 in stock
D5030 25 mg $410.00 in stock
E5030 50 mg $695.00 in stock

Cyanine7 azide is a near-infrared fluorescent dye azide for Click Chemistry labeling, an analog of Cy7® azide.

This product can be used for the incorporation of Cyanine7 into various alkynylated biomolecules via Click Chemistry. Post-synthetic modification of oligonucleotides is also possible with this azide.

Cyclohexane-bridged polymethyne chain allows for 20% increase in quantum yield (compared to parent non-bridged structure).

Cyanine7 absorbance and emission spectra

Cyanine7 absorbance and emission spectra

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Alkyne NHS ester for the labeling of biomolecules with alkyne group for Copper catalyzed Click chemistry.

General properties

Appearance: green powder / solution
Molecular weight: 667.33
CAS number: 1557149-65-1 (chloride), 1557397-59-7
Molecular formula: C40H51ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

Product citations

  1. Roberts, S.; Khera, E.; Choi, C.; Navaratna, T.; Grimm, J.; Thurber, G.M.; Reiner, T. Optoacoustic imaging of Glucagon-like Peptide 1 Receptor with a near-infrared exendin-4 analog. Journal of Nuclear Medicine, in press. doi: 10.2967/jnumed.120.252262
  2. Meka, R.R.; Venkatesha, S.H.; Moudgil, K.D. Peptide-directed liposomal delivery improves the therapeutic index of an immunomodulatory cytokine in controlling autoimmune arthritis. Journal of Controlled Release, 2018, 286, 279–288. doi: 10.1016/j.jconrel.2018.08.007
  3. Lyu, Z.; Kang, L.; Buuh, Z.Y.; Jiang, D.; McGuth, J.C.; Du, J.; Wissler, H.L.; Cai, W.; Wang, R.E. A Switchable Site-Specific Antibody Conjugate. ACS Chemical Biology, 2018, 13(4), 958–964. doi: 10.1021/acschembio.8b00107
  4. Maudens, P.; Seemayer, C.A.; Thauvin, C.; Gabay, C.; Jordan, O.; Allémann, E. Nanocrystal-Polymer Particles: Extended Delivery Carriers for Osteoarthritis Treatment. Small, 2018, 14(8), 1703108. doi: 10.1002/smll.201703108
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