Cyanine7 azide
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 15030 | 100 uL, 10 mM/DMSO | – | in stock | |
| 35030 | 500 uL, 10 mM/DMSO | $199 | in stock | |
| 45030 | 1 mL, 10 mM/DMSO |
$495
|
in stock | |
| A5030 | 1 mg | – | in stock | |
| B5030 | 5 mg | $199 | in stock | |
| C5030 | 10 mg | $297 | in stock | |
| D5030 | 25 mg |
$495
|
in stock | |
| E5030 | 50 mg |
$895
|
in stock |
Cyanine7 azide is a near-infrared fluorescent dye azide for click chemistry labeling, an analog of Cy7® azide.
This product can be used for the incorporation of Cyanine7 into various alkynylated biomolecules via click chemistry. Post-synthetic modification of oligonucleotides is also possible with this azide.
Cyclohexane-bridged polymethyne chain allows for 20% increase in quantum yield (compared to parent non-bridged structure).
Absorbance and emission spectra of Cyanine7
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THPTA ligand
THPTA is a water-soluble ligand for Cu(I)-catalyzed click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.Hexynoic acid NHS ester
Hexynoic acid NHS ester for the labeling of biomolecules with alkyne group for copper-catalyzed click chemistry.Copper(II)-TВTA catalytic buffer, 1.5x
Ready-to-use catalytic buffer containing сopper(II) and TBTA ligand. It is suitable for click chemistry modification of nucleic acids and small molecules.General properties
| Appearance: | green powder / solution |
| Molecular weight: | 667.33 |
| CAS number: | 1557149-65-1 (chloride), 1557397-59-7 |
| Molecular formula: | C40H51ClN6O |
| Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 750 |
| ε, L⋅mol−1⋅cm−1: | 199000 |
| Emission maximum, nm: | 773 |
| Fluorescence quantum yield: | 0.3 |
| CF260: | 0.022 |
| CF280: | 0.029 |
Product citations
- Shen, W.; You, T.; Xu, W.; Xie, Y.; Wang, Y.; Cui, M. Rapid and Widespread Distribution of Intranasal Small Extracellular Vesicles Derived from Mesenchymal Stem Cells throughout the Brain Potentially via the Perivascular Pathway. Pharmaceutics, 2023, 15(11), 2578. doi: 10.3390/pharmaceutics15112578
- Zeng, Y.; Shen, Y.; Wu, S.; Cai, L.; Wang, Z.; Cai, K.; Shen, J.; Hii Ru Yie, K.; Zhang, H.; Xu, L.; Liu, J. Bone-Targeting PLGA Derived Lipid Drug Delivery System Ameliorates Bone Loss in Osteoporotic Ovariectomized Rats. Materials & Design, 2022, 221, 110967. doi: 10.1016/j.matdes.2022.110967
- Roberts, S.; Khera, E.; Choi, C.; Navaratna, T.; Grimm, J.; Thurber, G.M.; Reiner, T. Optoacoustic imaging of Glucagon-like Peptide 1 Receptor with a near-infrared exendin-4 analog. Journal of Nuclear Medicine, 2021, 62(6), 839–848. doi: 10.2967/jnumed.120.252262
- Thauvin, C.; Maudens, P.; Allémann, E. Microwave-assisted synthesis of self-assembling bi-functionalizable amphiphilic diblock copolymers. Journal of Drug Delivery Science and Technology, 2021, 61, 102255. doi: 10.1016/j.jddst.2020.102255
Cy® is a trademark of GE Healthcare.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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