TFA-aminolinker C6 phosphoramidite

Cat. # Quantity Price Lead time
1777-100mg 100 mg $35.00 10 days
1777-250mg 250 mg $70.00 10 days
1777-1g 1 g $150.00 10 days
1777-5g 5 g $550.00 10 days
1777-10g 10 g $950.00 21 days

N-trifluoroacetyl (TFA) protected aminolink C6 phosphoramidite for the synthesis of 5'-amino-modified oligonucleotides. TFA protection is smoothly removed during ammonia deprotection, and does not require any additional steps. If necessary, the resulting oligonucleotides can be purified by ion exchange chromatography, or gel electrophoresis.

5'-terminal amino modified oligos are used for the production of DNA arrays, and for subsequent 5'-terminal modification with NHS esters.

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General properties

Appearance: colorless to yellowish liquid
Molecular weight: 413.42
CAS number: 133975-85-6
Molecular formula: C17H31N3F3O3P
Solubility: good in acetonitrile, THF, DCM
Quality control: NMR 1H, NMR 31P, functional testing
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Oligo synthesis details

Diluent: acetonitrile
Coupling conditions: standard coupling, identical to normal nucleobases
Deprotection conditions: identical to protected nucleobases
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