TFA-aminolinker C6 phosphoramidite
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 1777-100mg | 100 mg | $35.00 | in stock | |
| 1777-250mg | 250 mg | $70.00 | in stock | |
| 1777-1g | 1 g | $150.00 | in stock | |
| 1777-5g | 5 g |
$550.00
|
in stock | |
| 1777-10g | 10 g |
$950.00
|
in stock |
N-trifluoroacetyl (TFA) protected aminolink C6 phosphoramidite for the synthesis of 5'-amino-modified oligonucleotides. TFA protection is smoothly removed during ammonia deprotection, and does not require any additional steps. If necessary, the resulting oligonucleotides can be purified by ion exchange chromatography, or gel electrophoresis.
5'-terminal amino modified oligos are used for the production of DNA arrays, and for subsequent 5'-terminal modification with NHS esters.
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Spacer phosphoramidite 18 (hexaethylene glycol amidite) provides a long hydrophilic linker for oligo synthesis.General properties
| Appearance: | colorless to yellowish liquid |
| Molecular weight: | 413.42 |
| Molecular formula: | C17H31N3F3O3P |
| Solubility: | good in acetonitrile, THF, DCM |
| Quality control: | NMR 1H, NMR 31P, functional testing |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Oligo synthesis details
| Diluent: | acetonitrile |
| Coupling conditions: | standard coupling, identical to normal nucleobases |
| Deprotection conditions: | identical to protected nucleobases |
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