Product citations

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Yang, H.Y.; Jang, M.-S.; Li, Y.; Lee, J.H.; Lee, D.S. Multifunctional and Redox-Responsive Self-Assembled Magnetic Nanovectors for Protein Delivery and Dual-Modal Imaging. ACS Applied Materials & Interfaces, 2017, 9(22), 19184–19192. doi: 10.1021/acsami.7b03747
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Zhang, K.; Zhang, Y.; Li, Z.; Li, N.; Feng, N. Essential oil-mediated glycerosomes increase transdermal paeoniflorin delivery: optimization, characterization, and evaluation in vitro and in vivo. International Journal of Nanomedicine, 2017, 12, 3521–3532. doi: 10.2147/ijn.s135749
Lee, J.Y.; Kim, S.E.; Yun, Y.-P.; Choi, S.-W.; Jeon, D.-I.; Kim, H.-J.; Park, K.; Song, H.-R. Osteogenesis and new bone formation of alendronate-immobilized porous PLGA microspheres in a rat calvarial defect model. Journal of Industrial and Engineering Chemistry, 2017, 52, 277–286. doi: 10.1016/j.jiec.2017.03.057
Balasso, A.; Salmaso, S.; Pontisso, P.; Rosato, A.; Quarta, S.; Malfanti, A.; Mastrotto, F.; Caliceti, P. Re-programming pullulan for targeting and controlled release of doxorubicin to the hepatocellular carcinoma cells. European Journal of Pharmaceutical Sciences, 2017, 103, 104–115. doi: 10.1016/j.ejps.2017.02.016
Yang, X.; Wang, Z.; Xiang, Z.; Li, D.; Hu, Z.; Cui, W.; Geng, L.; Fang, Q. Peptide probes derived from pertuzumab by molecular dynamics modeling for HER2 positive tumor imaging. PLoS Computational Biology, 2017, 13(4), e1005441. doi: 10.1371/journal.pcbi.1005441
Han, Z.; Li, Y.; Roelle, S.; Zhou, Z.; Liu, Y.; Sabatelle, R.; DeSanto, A.; Yu, X.; Zhu, H.; Magi-Galluzzi, C.; Lu, Z.-R. A Targeted Contrast Agent Specific to an Oncoprotein in Tumor Microenvironment with the Potential for Detection and Risk Stratification of Prostate Cancer with MRI. Bioconjugate Chemistry, 2017, 28(4), 1031–1040. doi: 10.1021/acs.bioconjchem.6b00719
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Pan, Y.; Ren, X.; Wang, S.; Li, X.; Luo, X.; Yin, Z. Annexin V-Conjugated Mixed Micelles as a Potential Drug Delivery System for Targeted Thrombolysis. Biomacromolecules, 2017, 18(3), 865–876. doi: 10.1021/acs.biomac.6b01756
Alqahtani, M.S.; Islam, M.S.; Podaralla, S.; Kaushik, R.S.; Reineke, J.J.; Woyengo, T.; Perumal, O. Food Protein-based Core-Shell Nanocarriers for Oral Drug Delivery: Effect of Shell Composition on in-vitro and in-vivo Functional Performance of Zein Nanocarriers. Molecular Pharmaceutics, 2017, 14(3), 757–769. doi: 10.1021/acs.molpharmaceut.6b01017
Mandracchia, D.; Rosato, A.; Trapani, A.; Chlapanidas, T.; Montagner, I.M.; Perteghella, S.; Di Franco, C.; Torre, M.L.; Trapani, G.; Tripodo, G. Design, synthesis and evaluation of biotin decorated inulin-based polymeric micelles as long-circulating nanocarriers for targeted drug delivery. Nanomedicine: Nanotechnology, Biology, and Medicine, 2017, 13(3), 1245–1254. doi: 10.1016/j.nano.2017.01.001
Zhao, Lei and Chen, Guojun and Li, Jun and Fu, Yingmei and Mavlyutov, Timur A. and Yao, Annie and Nickells, Robert W. and Gong, Shaoqin and Guo, Lian-Wang. An intraocular drug delivery system using targeted nanocarriers attenuates retinal ganglion cell degeneration. Journal of Controlled Release, 2017, 247, 153–166. doi: 10.1016/j.jconrel.2016.12.038
Braunová A.; Kostka, L.; Sivák, L.; Cuchalová, L.; Hvězdová, Z.; Laga, R.; Filippov, S.; Černoch, P.; Pechar, M.; Janoušková, O.; Šírová, M.; Etrych, T. Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance. Journal of Controlled Release, 2017, 245, 41–51. doi: 10.1016/j.jconrel.2016.11.020
Suarato, G.; Lee, S.-I.; Li, W.; Rao, S.; Khan, T.; Meng, Y.; Shelly, M. Micellar nanocomplexes for biomagnetic delivery of intracellular proteins to dictate axon formation during neuronal development. Biomaterials, 2017, 112, 176–191. doi: 10.1016/j.biomaterials.2016.09.035
Yang, Q.; Wu, L.; Li, L.; Zhou, Z.; Huang, Y. Subcellular co-delivery of two different site-oriented payloads for tumor therapy. Nanoscale, 2017, 9(4), 1547–1558. doi: 10.1039/c6nr08200a
Beldman, T.J.; Senders, M.L.; Alaarg, A.; Perez-Medina, C.; Tang, J.; Zhao, Y.; Fay, F.; Deichmöller, J.; Born, B.; Desclos, E.; van der Wel, N.N.; Hoebe, R.A.; Kohen, F.; Kartvelishvily, E.; Neeman, M.; Reiner, T.; Calcagno, C.; Fayad, Z.A.; de Winther, M.P.J.; Lutgens, E.; Mulder, W.J.M.; Kluza, E. Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis. ACS Nano, 2017, 11(6), 5785–5799. doi: 10.1021/acsnano.7b01385
Zhou, Z.; Liu, Y.; Wu, L.; Li, L.; Huang, Y. Enhanced nuclear delivery of anti-cancer drugs using micelles containing releasable membrane fusion peptide and nuclear-targeting retinoic acid. Journal of Materials Chemistry B, 2017, 5(34), 7175–7185. doi: 10.1039/C7TB01177F
Koziolová, E.; Machová, D.; Pola, R.; Janoušková, O.; Chytil, P.; Laga, R.; Filippov, S.K.; Šubr, V.; Etrych, T.; Pechar, M. Micelle-forming HPMA copolymer conjugates of ritonavir bound via a pH-sensitive spacer with improved cellular uptake designed for enhanced tumor accumulation. Journal of Materials Chemistry B, 2016, 4(47), 7620–7629. doi: 10.1039/C6TB02225A
Yan, Y.; Liu, L.; Xiong, H.; Miller, J.B.; Zhou, K.; Kos, P.; Huffman, K.E.; Elkassih, S.; Norman, J.W.; Carstens, R.; Kim, J.; Minna, J.D.; Siegwart, D.J. Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells. Proceedings of the National Academy of Sciences of the U.S.A., 2016, 113(39), E5702–E5710. doi: 10.1073/pnas.1606886113
Cao, T.; You, P.; Zhou, X.; Luo, J.; Xu, X.; Zhou, Z.; Yang, S.; Zhang, Y.; Yang, H.; Wang, M. Visualization of size-dependent tumour retention of PEGylated nanographene oxide via SPECT imaging. Journal of Materials Chemistry B, 2016, 4(39), 6446–6453. doi: 10.1039/c6tb01892k
Ye, Y.; Wang, J.; Hu, Q.; Hochu, G.M.; Xin, H.; Wang, C.; Gu, Z. Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors. ACS Nano, 2016, 10(9), 8956–8963. doi: 10.1021/acsnano.6b04989
Chen, Y.; Li, Y.; Shen, W.; Li, K.; Yu, L.; Chen, Q.; Ding, J. Controlled release of liraglutide using thermogelling polymers in treatment of diabetes. Scientific Reports, 2016, 6, 31593. doi: 10.1038/srep31593
Sun, Y.; Hong, S.; Ma, X.; Cheng, K.; Wang, J.; Zhang, Z.; Yang, M.; Jiang, Y.; Hong, X.; Cheng, Z. Recyclable Cu(I)/Melanin Dots for Cycloadditions, Bioconjugation and Cell Labeling. Chemical Science, 2016, 7(9), 5888–5892. doi: 10.1039/c6sc01536k
Jiang, X.; Bugno, J.; Hu, C.; Yang, Y.; Herold, T.; Qi, J.; Chen, P.; Gurbuxani, S.; Arnovitz, S.; Strong, J.; Ferchen, K.; Ulrich, B.; Weng, H.; Wang, Y.; Huang, H.; Li, S.; Neilly, M.B.; Larson, R.A.; Le Beau, M.M.; Bohlander, S.K.; Jin, J.; Li, Z.; Bradner, J.E.; Hong, S.; Chen, J. Eradication of acute myeloid leukemia with FLT3 ligand-targeted miR-150 nanoparticles. Cancer Research, 2016, 76(15), 4470–4480. doi: 10.1158/0008-5472.CAN-15-2949
Zhang, Y.; Li, Z.; Zhang, K.; Yang, G.; Wang, Z.; Zhao, J.; Hu, R.; Feng, N. Ethyl oleate-containing nanostructured lipid carriers improve oral bioavailability of trans-ferulic acid ascompared with conventional solid lipid nanoparticles. International Journal of Pharmaceutics, 2016, 511(1), 57–64. doi: 10.1016/j.ijpharm.2016.06.131
Wang, C.; Wang, X.; Dong, K.; Luo, J.; Zhang, Q.; Cheng, Y. Injectable and Responsively Degradable Hydrogel for Personalized Photothermal Therapy. Biomaterials, 2016, 104, 129–137. doi: 10.1016/j.biomaterials.2016.07.013
Kim, K.-M.; Kim, M.K.; Paek, H.-J.; Choi, S.-J.; Oh, J.-M. Stable fluorescence conjugation of ZnO nanoparticles and their size dependent cellular uptake. Colloids and Surfaces B: Biointerfaces, 2016, 145, 870–877. doi: 10.1016/j.colsurfb.2016.06.006
Geng, L.; Wang, Z.; Jia, X.; Han, Q.; Xiang, Z.; Li, D.; Yang, X.; Zhang, D.; Bu, X.; Wang, W.; Hu, Z.; Fang, Q. HER2 Targeting Peptides Screening and Applications in Tumor Imaging and Drug Delivery. Theranostics, 2016, 6(8), 1261–1273. doi: 10.7150/thno.14302
Yang, Q.; Li, L.; Sun, W.; Zhou, Z.; Huang, Y. Dual Stimuli-Responsive Hybrid Polymeric Nanoparticles Self-Assembled from POSS-Based Star-Like Copolymer-Drug Conjugates for Efficient Intracellular Delivery of Hydrophobic Drugs. ACS Applied Materials & Interfaces, 2016, 8(21), 13251–13261. doi: 10.1021/acsami.6b02403
Brinkman, A.M.; Chen, G.; Wang, Y.; Hedman, C.J.; Sherer, N.M.; Havighurst, T.C.; Gong, S.; Xu, W. Aminoflavone-Loaded EGFR-Targeted Unimolecular Micelle Nanoparticles Exhibit Anti-Cancer Effects in Triple Negative Breast Cancer. Biomaterials, 2016, 101, 20–31. doi: 10.1016/j.biomaterials.2016.05.041
Bygd, H.C.; Bratlie, K.M. The effect of chemically modified alginates on macrophage phenotype and biomolecule transport. Journal of Biomedical Materials Research, 2016, 104(7), 1707–1719. doi: 10.1002/jbm.a.35700
Zhao, L.; Yuan, W.; Ang, C.Y.; Qu, Q.; Dai, Y.; Gao, Y.; Luo, Z.; Wang, J.; Chen, H.; Li, M.; Li, F.; Zhao, Y. Silica-Polymer Hybrid with Self-Assembled PEG Corona Excreted Rapidly via a Hepatobiliary Route. Advanced Functional Materials, 2016, 26(18), 3036–3047. doi: 10.1002/adfm.201505155
Al-Hilal, T.A.; Chung, S.W.; Choi, J.U.; Alam, F.; Park, J.; Kim, S.W.; Kim, S.Y.; Ahsan, F.; Kim, I.-S.; Byun, Y. Targeting prion-like protein doppel selectively suppresses tumor angiogenesis. Journal of Clinical Investigation, 2016, 126(4), 1251–1266. doi: 10.1172/JCI83427
Jiang, X.; Hu, C.; Arnovitz, S.; Bugno, J.; Yu, M.; Zuo, Z.; Chen, P.; Huang, H.; Ulrich, B.; Gurbuxani, S.; Weng, H.; Strong, J.; Wang, Y.; Li, Y.; Salat, J.; Li, S.; Elkahloun, A.G.; Yang, Y.; Neilly, M.B.; Larson, R.A.; Le Beau, M.M.; Herold, T.; Bohlander, S.K.; Liu, P.P.; Zhang, J.; Li, Z.; He, C.; Jin, J.; Hong, S.; Chen, J.;. miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia. Nature Communications, 2016, 7, 11452. doi: 10.1038/ncomms11452
Kim, J.B.; Park, K.; Ryu, Ji.; Lee, J.J.; Lee, M.W.; Cho, H.S.; Nam, H.S.; Park, O.K.; Song, J.W.; Kim, T.S.; Oh, D.J.; Gweon, D.; Oh, W.-Y.; Yoo, H.; Kim, J.W. Intravascular optical imaging of high-risk plaques in vivo by targeting macrophage mannose receptors. Scientific Reports, 2016, 6, 22608. doi: 10.1038/srep22608
Cai, X.; Jin, R.; Wang, J.; Yue, D.; Jiang, Q.; Wu, Y.; Gu, Z. Bioreducible Fluorinated Peptide Dendrimers Capable of Circumventing Various Physiological Barriers for Highly Efficient and Safe Gene Delivery. ACS Applied Materials & Interfaces, 2016, 8(9), 5821–5832. doi: 10.1021/acsami.5b11545
Ma, G.; Zhao, Z.; Liu, H. Yeast Cells Encapsulating Polymer Nanoparticles as Trojan Particles via in Situ Polymerization inside Cells. Macromolecules, 2016, 49(5), 1545–1551. doi: 10.1021/acs.macromol.6b00016
Rabinsky, E.F.; Joshi, B.P.; Pant, A.; Zhou, J.; Duan, X.; Smith, A.; Kuick, R.; Fan, S.; Nusrat, A.; Owens, S.R.; Appelman, H.D.; Wang, T.D. Overexpressed claudin-1 can be endoscopically visualized in colonic adenomas in vivo. CMGH Cellular and Molecular Gastroenterology and Hepatology, 2016, 2(2), 222–237. doi: 10.1016/j.jcmgh.2015.12.001
Joshi, B.P.; Zhou, J.; Pant, A.; Duan, X.; Zhou, Q.; Kuick, R.; Owens, S.R.; Appelman, H.; Wang, T.D. Design and Synthesis of Near-Infrared Peptide for in Vivo Molecular Imaging of HER2. Bioconjugate Chemistry, 2016, 27(2), 481–494. doi: 10.1021/acs.bioconjchem.5b00565
Khaliq, N.U.; Park, D.Y.; Lee, J.Y.; Joo, Y.; Oh, K.S.; Kim, J.S.; Kim, J.-S.; Kim, I.-S.; Kwon, I.C.; Yuk, S.H. The multilayer nanoparticles for deep penetration of docetaxel into tumor parenchyma to overcome tumor microenvironment. Colloids and Surfaces B: Biointerfaces, 2016, 146, 833–840. doi: 10.1016/j.colsurfb.2016.07.034
Hu, H.; Li, Y.; Zhou, Q.; Ao, Y.; Yu, C.; Wan, Y.; Xu, H.-B.; Li, Z.; Yang, X. Redox-sensitive hydroxyethyl starch-doxorubicin conjugate for tumor targeted drug delivery. ACS Applied Materials & Interfaces, 2016, 8(45), 30833–30844. doi: 10.1021/acsami.6b11932
Chen, Y.; Luan, J.; Shen, W.; Lei, K.; Yu, L.; Ding, J. Injectable and thermosensitive hydrogel containing liraglutide as a long-acting anti-diabetic system. ACS Applied Materials & Interfaces, 2016, 8(45), 30703–30713. doi: 10.1021/acsami.6b09415
Alam, F.; Chung, S.W.; Hwang, S.R.; Kim, J.-y.; Park, J.; Moon, H.T.; Byun, Y. Preliminary safety evaluation of a taurocholate-conjugated low-molecular-weight heparin derivative (LHT7): a potent angiogenesis inhibitor. Journal of Applied Toxicology, 2015, 35(1), 104–115. doi: 10.1002/jat.2995
Wang, H.; Li, D.; Liu, S.; Liu, R.; Yuan, H.; Krasnoperov, V.; Shan, H.; Conti, P.S.; Gill, P.S.; Li, Z. Small-Animal PET Imaging of Pancreatic Cancer Xenografts Using a ⁶⁴Cu-Labeled Monoclonal Antibody, MAb159. Journal of Nuclear Medicine, 2015, 56(6), 908–913. doi: 10.2967/jnumed.115.155812
Zhou, B.; Wang, H.; Liu, R.; Wang, M.; Deng, H.; Giglio, B.; Gill, P.S.; Shan, H.; Li, Z. PET Imaging of Dll4 Expression in Glioblastoma and Colorectal Cancer Xenografts Using ⁶⁴Cu-Labeled Monoclonal Antibody 61B. Molecular Pharmaceutics, 2015, 12(10), 3527–3534. doi: 10.1021/acs.molpharmaceut.5b00105
Geng, L.; Wang, Z.; Yang, X.; Li, D.; Lian, W.; Xiang, Z.; Wang, W.; Bu, X.; Lai, W.; Hu, Z.; Fang, Q. Structure-based Design of Peptides with High Affinity and Specificity to HER2 Positive Tumors. Theranostics, 2015, 5(10), 1154–1165. doi: 10.7150/thno.12398
Chung, S.W.; Lee, B.S. Choi, J.U.; Kim, S.W.; Kim, I.-S.; Kim, S.Y.; Byun, Y. Optimization of a stable linker involved DEVD peptide-doxorubicin conjugate that is activated upon radiation-induced caspase-3-mediated apoptosis. Journal of Medicinal Chemistry, 2015, 58(16), 6435–6447. doi: 10.1021/acs.jmedchem.5b00420
Li, L.; Sun, W.; Zhong, J.; Yang, Qi.; Zhu, X.; Zhou, Z.; Zhang Z.; Huang, Y. Multistage Nanovehicle Delivery System Based on Stepwise Size Reduction and Charge Reversal for Programmed Nuclear Targeting of Systemically Administered Anticancer Drugs. Advanced Functional Materials, 2015, 25(26), 4101–4113. doi: 10.1002/adfm.201501248
Zhou, J.; Joshi, B.P.; Duan, X.; Pant, A.; Qiu, Z.; Kuick, R.; Owens, S.R.; Wang, T.D. EGFR Overexpressed in Colonic Neoplasia Can be Detected on Wide-Field Endoscopic Imaging. Clinical and Translational Gastroenterology, 2015, 6, e101. doi: 10.1038/ctg.2015.28
Arami, H.; Khandhar, A.P.; Tomitaka, A.; Yu, E.; Goodwill, P.W.; Conolly, S.M.; Krishnan, K.M. In vivo multimodal magnetic particle imaging (MPI) with tailored magneto/optical contrast agents. Biomaterials, 2015, 52, 251–261. doi: 10.1016/j.biomaterials.2015.02.040
Mahoney, D.; Owens, E.A.; Fan, C.; Hsiang, J.-C.; Henary, M.; Dickson, R.M. Tailoring Cyanine Dark States for Improved Optically Modulated Fluorescence Recovery. The Journal of Physical Chemistry B, 2015, 119(13), 4637–4643. doi: 10.1021/acs.jpcb.5b00777
Bygd, H.C.; Forsmark, K.D.; Bratlie, K.M. Altering in vivo macrophage responses with modified polymer properties. Biomaterials, 2015, 56, 187–197. doi: 10.1016/j.biomaterials.2015.03.042
Hou, Z.; Lin, J.; Li, Y.; Guo, F.; Yu, F.; Wu, H.; Fan, Z.; Zhi, L.; Luo, F. Validation of a dual role of methotrexate-based chitosan nanoparticles in vivo. RSC Advances, 2015, 5(52), 41393–41400. doi: 10.1039/c5ra03705K
Ruan, S.; He, Q.; Gao, H. Matrix metalloproteinase triggered size-shrinkable gelatin-gold fabricated nanoparticles for tumor microenvironment sensitive penetration and diagnosis of glioma. Nanoscale, 2015, 7, 9487–9496. doi: 10.1039/c5nr01408e
Kim, M.-G.; Park, J.Y.; Miao, W.; Lee, J.; Oh, Y.-K. Polyaptamer DNA nanothread-anchored, reduced graphene oxide nanosheets for targeted delivery. Biomaterials, 2015, 48, 129–136. doi: 10.1016/j.biomaterials.2015.01.009
Cai, H.; Singh, A.N.; Sun, X.; Peng, F. Synthesis and Characterization of Her2-NLP Peptide Conjugates Targeting Circulating Breast Cancer Cells: Cellular Uptake and Localization by Fluorescent Microscopic Imaging. Journal of Fluorescence, 2015, 25(1), 113–117. doi: 10.1007/s10895-014-1486-9
Yang, Q.; Li, L.; Zhu, X.; Sun, W.; Zhou, Z.; Huang, Y. The impact of the HPMA polymer structure on the targeting performance of the conjugated hydrophobic ligand. RSC Advances, 2015, 5(19), 14858–14870. doi: 10.1039/c4ra16085a
Cai, L.; Dewi, R.E.; Heilshorn, S.C. Injectable Hydrogels with In Situ Double Network Formation Enhance Retention of Transplanted Stem Cells. Advanced Functional Materials, 2015, 25(9), 1344–1351. doi: 10.1002/adfm.201403631
Jeong, J.-H. Molecular imaging monitoring of poly(ethylene glycol) conjugated islets for evaluation of islet graft rejection. Archives of Pharmacal Research, 2015, 38(5), 785–790. doi: 10.1007/s12272-014-0412-7
Wang, X.; Huang, S.S.; Heston, W.D.W.; Guo, H.; Wang, B.-C.; Basilion, J.P. Development of Targeted Near-Infrared Imaging Agents for Prostate Cancer. Molecular Cancer Therapeutics, 2014, 13(11), 2595–2606. doi: 10.1158/1535-7163.mct-14-0422
Kim, H.S.; Yoo, H.S. Surface-polymerized biomimetic nanofibrils for the cell-directed association of 3-D scaffolds. Chemical Communications, 2014, 51, 306–309. doi: 10.1039/c4cc06875k
Al-Hilal, T.A.; Alam, F.; Park, J.W.; Kim, K.; Kwon, I.C.; Ryu, G.H.; Byun, Y. Prevention effect of orally active heparin conjugate on cancer-associated thrombosis. Journal of Controlled Release, 2014, 195, 155-161. doi: 10.1016/j.jconrel.2014.05.027
Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
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