Cyanine5.5 NHS ester
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
17020 | 1 mg | $125 | in stock | |
27020 | 5 mg | $260 | in stock | |
47020 | 25 mg | $510 | in stock | |
57020 | 50 mg | $895 | in stock | |
67020 | 100 mg | $1490 | in stock |
Cyanine5.5 NHS ester is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides, an analog of Cy5.5® NHS ester.
Cy5.5 is a far-red (and near-infrared) emitting dye which is ideal for fluorescence measurements where background fluorescence is a concern. It is also suitable for in vivo NIR imaging experiments.
This reagent can replace NHS esters of Cy5.5® and DyLight 680.
Cy5.5 absorbance and emission spectra
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Ready-to-use catalytic buffer containing сopper(II) and TBTA ligand. It is suitable for click chemistry modification of nucleic acids and small molecules.FAM azide, 5-isomer
FAM (fluorescein) azide for сlick chemistry labeling, pure 5-isomer.sulfo-Cyanine5 tetrazine
Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.General properties
Appearance: | dark blue to violet solid |
Molecular weight: | 767.66 |
CAS number: | 2375105-86-3 |
Molecular formula: | C44H46N3BF4O4 |
IUPAC name: | 1H-Benz[e]indolium, 2-[5-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)-1,3-pentadien-1-yl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl- |
Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L) |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 684 |
ε, L⋅mol−1⋅cm−1: | 198000 |
Emission maximum, nm: | 710 |
Fluorescence quantum yield: | 0.2 |
CF260: | 0.07 |
CF280: | 0.03 |
Product citations
- Di, G.; Miao, L.; Yu, C.; Guan, G.; Luan, X.; Jin, X.; Pan, M.; Yang, Y.; Yan, J.; Chen, P. Extracellular Vesicles Containing GAS6 Protect the Liver from Ischemia-Reperfusion Injury by Enhancing Macrophage Efferocytosis via MerTK-ERK-COX2 Signaling. Research Square, 2024, preprint. doi: 10.21203/rs.3.rs-4423503/v1
- Lim, S.; Ha, Y.; Lee, B.; Shin, J.; Rhim, T. Calnexin as a dual-role biomarker: antibody-based diagnosis and therapeutic targeting in lung cancer. BMB Reports, 2024, 57(3), 155-160. doi: 10.5483/BMBRep.2023-0228
- Yun, W.S.; Yang, W.; Shim, M.K.; Song, S.; Choi, J.; Kim, J.; Kim, J.; Moon, Y.; Jo, S.H.; Lim, D.-K.; Kim, K. Accurately controlled tumor temperature with silica-coated gold nanorods for optimal immune checkpoint blockade therapy. Biomaterials Research, 2024, 28, 0024. doi: 10.34133/bmr.0024
- Guo, H.; Mukwaya, V.; Wu, D.; Xiong, S.; Dou, H. Acid-Responsive Decomposable Nanomedicine Based on Zeolitic Imidazolate Frameworks for Near-Infrared Fluorescence Imaging/Chemotherapy Combined Tumor Theranostics. Pharmaceutics, 2024, 16(6), 823. doi: 10.3390/pharmaceutics16060823
Cy® is a trademark of Cytiva.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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