Cyanine5.5 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 17020 | 1 mg | $110.00 | in stock | |
| 27020 | 5 mg | $210.00 | in stock | |
| 47020 | 25 mg |
$410.00
|
in stock | |
| 57020 | 50 mg |
$695.00
|
in stock | |
| 67020 | 100 mg |
$1190.00
|
in stock |
Cyanine5.5 NHS ester is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides, an analog of Cy5.5® NHS ester.
Cy5.5 is a far-red (and near-infrared) emitting dye which is ideal for fluorescence measurements where background fluorescence is a concern. It is also suitable for in vivo NIR imaging experiments.
This reagent can replace NHS esters of Cy5.5®, Alexa Fluor 680, and DyLight 680.
Cy5.5 absorbance and emission spectra
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Carbonyl reactive NIR fluorophore for the labeling of aldehydes, ketones, including glycoproteins subjected to periodate oxidation.General properties
| Appearance: | dark blue solid |
| Molecular weight: | 767.66 |
| CAS number: | 1469277-96-0, 2054318-82-8 (chloride); 1469541-53-4, 1874250-60-8 (without anion) |
| Molecular formula: | C44H46N3BF4O4 |
| IUPAC name: | 1H-Benz[e]indolium, 2-[5-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)-1,3-pentadien-1-yl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl- |
| Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L) |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation maximum, nm: | 684 |
| ε, L⋅mol−1⋅cm−1: | 198000 |
| Emission maximum, nm: | 710 |
| Fluorescence quantum yield: | 0.2 |
| CF260: | 0.07 |
| CF280: | 0.03 |
Product citations
- Feng, C.; Ouyang, J.; Tang, Z.; Kong, N.; Liu, Y.; Fu, L.; Ji, X.; Xie, T.; Farokhzad, O.C.; Tao, W. Germanene-Based Theranostic Materials for Surgical Adjuvant Treatment: Inhibiting Tumor Recurrence and Wound Infection. Matter, in press. doi: 10.1016/j.matt.2020.04.022
- Xu, J.; Guo, J.; Golob-Schwarzl, N.; Haybaeck, J.; Qiu, X.; Hildebrandt, N. Single-measurement multiplexed quantification of microRNAs from human tissue using catalytic hairpin assembly and Förster resonance energy transfer. ACS Sensors, in press. doi: 10.1021/acssensors.0c00432
- Xu, N.; Yang, Y.-F.; Chen, L.; Lin, J. A Ferritin–Albumin–Cu Nanoparticle that Efficaciously Delivers Copper(II) Ions to a Tumor and Improves the Therapeutic Efficacy of Disulfiram. ACS Omega, 2020, 5(18), 10415–10422. doi: 10.1021/acsomega.0c00293
- Ko, Y.J.; Lee, J.W.; Kim, H.; Cho, E.; Yang, Y.; Kim, I.-S.; Kim, S.H.; Kwon, I.C. Versatile activatable vSIRPα-probe for cancer-targeted imaging and macrophage-mediated phagocytosis of cancer cells. Journal of Controlled Release, 2020, 323, 376–386. doi: 10.1016/j.jconrel.2020.04.037
Cy® is a trademark of GE Healthcare.
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