Biotin phosphoramidite (hydroxyprolinol)

Biotinylation Phosphoramidites

Cat. #	Quantity	Price	Lead time
22360 / Easily soluble lyophilised form in 8 mL septum	250 mg	$240	in stock
42360 / Easily soluble lyophilised form in 30 mL septum	1 g	$760	in stock
62360	5 g	$3040	in stock
82360	10 g	please inquire	in stock

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Non-nucleosidic modifier reagent for the synthesis of biotinylated oligos based on a hydroxyprolinol core. This phosphoramidite contains a dimethoxytrityl protective group for the purification of the resulting oligos on C₁₈ cartridges, and reverse phase HPLC. This modifier reagent can be used to introduce biotin onto 5'-position, 3'-position (using universal CPG), and internal oligo sites.

This amidite does not require special condensation and deprotection conditions.

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General properties

Appearance:	white powder
Molecular weight:	959.18
Molecular formula:	C₅₁H₇₁N₆O₈PS
Solubility:	good in MeCN, DCM, THF
Quality control:	NMR ¹H, ³¹P, HPLC-MS (95%), functional testing in oligo synthesis
Storage conditions:	Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	Download
	Product specifications

Oligo synthesis details

Diluent:	acetonitrile
Coupling conditions:	standard coupling, identical to normal nucleobases
Deprotection conditions:	identical to protected nucleobases

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.