Biotin phosphoramidite (hydroxyprolinol)
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 22360 | 250 mg | $240 | in stock | |
| 42360 | 1 g |
$760
|
in stock | |
| 62360 | 5 g |
$3040
|
in stock | |
| 82360 | 10 g | please inquire | in stock |
Non-nucleosidic modifier reagent for the synthesis of biotinylated oligos based on a hydroxyprolinol core. This phosphoramidite contains a dimethoxytrityl protective group for the purification of the resulting oligos on C18 cartridges, and reverse phase HPLC. This modifier reagent can be used to introduce biotin onto 5'-position, 3'-position (using universal CPG), and internal oligo sites.
This amidite does not require special condensation and deprotection conditions.
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General properties
| Appearance: | white powder |
| Molecular weight: | 959.18 |
| Molecular formula: | C51H71N6O8PS |
| Solubility: | good in MeCN, DCM, THF |
| Quality control: | NMR 1H, 31P, HPLC-MS (95%), functional testing in oligo synthesis |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Oligo synthesis details
| Diluent: | acetonitrile |
| Coupling conditions: | standard coupling, identical to normal nucleobases |
| Deprotection conditions: | identical to protected nucleobases |
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