Biotin phosphoramidite (hydroxyprolinol)

Cat. # Quantity Price Lead time
22360 250 mg $240.00 5 days
42360 1 g $760.00 in stock
62360 5 g $3040.00 in stock
82360 10 g please inquire in stock

Non-nucleosidic modifier reagent for the synthesis of biotinylated oligos based on a hydroxyprolinol core. This phosphoramidite contains a dimethoxytrityl protective group for the purification of the resulting oligos on C18 cartridges, and reverse phase HPLC. This modifier reagent can be used to introduce biotin onto 5'-position, 3'-position (using universal CPG), and internal oligo sites.

This amidite does not require special condensation and deprotection conditions.

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General properties

Appearance: white powder
Molecular weight: 959.18
Molecular formula: C51H71N6O8PS
Solubility: good in MeCN, DCM, THF
Quality control: NMR 1H, 31P, HPLC-MS (95%), functional testing in oligo synthesis
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Oligo synthesis details

Diluent: acetonitrile
Coupling conditions: standard coupling, identical to normal nucleobases
Deprotection conditions: identical to protected nucleobases
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