Phosphate CPG 500 solid support
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 13860 | 100 mg | $40.00 | in stock | |
| 43860 | 1 g | $190.00 | 5 days |
Phosphate CPG is a solid support for the synthesis of 3'-phosphorylated oligonucleotides. The phosphate group can be used as a blocking functionality to prevent 3'-5' exonuclease activity of some polymerases.
Upon cleavage from the support, a phosphate group remains at the 3' end of the oligonucleotide. It does not require any changes in oligo synthesis and deprotection protocols.
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TFA-Amino modifier CPG 500
TFA-amino modifier CPG for oligo synthesis. 500 Å, high load controlled pore glass.THPTA ligand
THPTA is a water soluble ligand for Cu(I) catalyzed Click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.General properties
| Appearance: | off-white beads |
| Quality control: | NMR 1H, HPLC-MS (95%) of bound reagent, loading measurement, functional testing (oligo synthesis) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Oligo synthesis details
| Pore size, Å: | 500 |
| Typical loading, umol/g: | 50−80 |
| Coupling conditions: | standard coupling, identical to normal nucleobases |
| Cleavage conditions: | ammonia, 2 h at room temperature |
| Deprotection conditions: | identical to protected nucleobases |
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