Cyanine3 amine
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 110C0 | 1 mg | $125 | in stock | |
| 210C0 | 5 mg | $260 | in stock | |
| 410C0 | 25 mg |
$510
|
in stock | |
| 510C0 | 50 mg |
$895
|
in stock | |
| 610C0 | 100 mg |
$1490
|
in stock |
Cyanine3 amine is a functionalized cyanine dye containing a free amino group. Cyanine3 is an analog of Cy3®.
Amino group of this reagent can be conjugated with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides.
The amino dye is supplied in salt form, and possesses some aqueous solubility.
Cyanine3 absorption and emission spectra
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Cyanine3 hydrazide with sulfo groups, well soluble in water and readily reacting with carbonyl compounds.Cyanine5.5 DBCO
Cyanine5.5 is a far-red / NIR emitting dye that is useful for bioimaging studies. Cyanine5.5 DBCO is a derivative of the dye with a cycloalkyne moiety for copper-free click chemistry.
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General properties
| Appearance: | red powder |
| Molecular weight: | 627.73 |
| CAS number: | 2247688-56-6 |
| Molecular formula: | C36H52Cl2N4O |
| IUPAC name: | 3H-Indolium, 1-[6-[(6-aminohexyl)amino]-6-oxohexyl]-2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propen-1-yl]-3,3-dimethyl-, chloride, hydrochloride (1:1:1) |
| Solubility: | moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols) |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 555 |
| ε, L⋅mol−1⋅cm−1: | 150000 |
| Emission maximum, nm: | 570 |
| Fluorescence quantum yield: | 0.31 |
| CF260: | 0.04 |
| CF280: | 0.09 |
Product citations
- Gorshkova, M.; Vanchugova, L.; Osipova, N.; Nikitin, A.; Kotova, J.; Kovalenko, E.; Ermolenko, Y.; Malinovskaya, J.; Kovshova, T.; Gelperina, S. Hybrid DIVEMA/PLGA nanoparticles as the potential drug delivery system. Research Square, 2024, preprint. doi: 10.21203/rs.3.rs-4594368/v1
- Ruan, Z.; Li, S.; Grigoropoulos, A.; Amiri, H.; Hilburg, S. L.; Chen, H.; Jayapurna, I.; Jiang, T.; Gu, Z.; Alexander-Katz, A.; Bustamante, C.; Huang, H.; Xu, T. Population-Based Heteropolymer Design to Mimic Protein Mixtures. Nature, 2023, 615(7951), 251–258. doi: 10.1038/s41586-022-05675-0
- Nizamov, T. R.; Iliasov, A. R.; Vodopyanov, S. S.; Kozhina, I. V.; Bordyuzhin, I. G.; Zhukov, D. G.; Ivanova, A. V.; Permyakova, E. S.; Mogilnikov, P. S.; Vishnevskiy, D. A.; Shchetinin, I. V.; Abakumov, M. A.; Savchenko, A. G. Study of Cytotoxicity and Internalization of Redox-Responsive Iron Oxide Nanoparticles on PC-3 and 4T1 Cancer Cell Lines. Pharmaceutics, 2023, 15(1), 127. doi: 10.3390/pharmaceutics15010127
- Malinovskaya, J.; Salami, R.; Valikhov, M.; Vadekhina, V.; Semyonkin, A.; Semkina, A.; Abakumov, M.; Harel, Y.; Levy, E.; Levin, T.; Persky, R.; Chekhonin, V.; Lellouche, J.-P.; Melnikov, P.; Gelperina, S. Supermagnetic Human Serum Albumin (HSA) Nanoparticles and PLGA-Based Doxorubicin Nanoformulation: A Duet for Selective Nanotherapy. International Journal of Molecular Sciences, 2023, 24(1), 627. doi: 10.3390/ijms24010627
Cy® is a trademark of GE Healthcare.
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