Sulfo-Cyanine5 maleimide

Cat. # Quantity Price Lead time
13380 1 mg $110.00 in stock
23380 5 mg $290.00 in stock
43380 25 mg $690.00 5 days
53380 50 mg $1270.00 in stock
63380 100 mg $1990.00 in stock

A water soluble, hydrophilic sulfo-Cyanine5 maleimide (Cy5® maleimide analog). We recommend this product for protein labeling, including labeling of antibodies as a perfect replacement for Cy5® maleimide. Labeled proteins can be easily separated from unreacted dye by gel filtration, spin column purification, dialysis, electrophoresis or chromatography.

An analog without sulfo groups, Cyanine5 maleimide, is also available.

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 absorbance and emission spectra

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General properties

Appearance: dark blue powder
Molecular weight: 803.00
CAS number: 2242791-82-6 (potassium salt); 2130955-10-9 (inner salt); 2242791-81-5 (inner salt); 2301999-22-2 (sodium salt)
Molecular formula: C38H43KN4O9S2
Solubility: soluble in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

Product citations

  1. Cioloboc, D.; Kurtz, D.M. Targeted cancer cell delivery of arsenate as a reductively activated prodrug. Journal of Biological Inorganic Chemistry, in press. doi: 10.1007/s00775-020-01774-3
  2. Baranova, N.; Radler, P.; Hernández-Rocamora, V.M.; Alfonso, C.; López-Pelegrin, M.; Rivas, G.; Vollmer, W.; Loose, M. Diffusion and capture permits dynamic coupling between treadmilling FtsZ filaments and cell division proteins. Nature Microbiology, 2020, 5, 407–417. doi: 10.1038/s41564-019-0657-5
  3. Ji, W.; Smith, P.N.; Koepsel, R.R.; Andersen, J.D.; Baker, S.L.; Zhang, L.; Carmali, S.; Myerson, J.W.; Muzykantov, V.; Russell, A.J. Erythrocytes as Carriers of Immunoglobulin-Based Therapeutics. Acta Biomaterialia, 2020, 101, 422–435. doi: 10.1016/j.actbio.2019.10.027
  4. Cliff, L.; Chadda, R.; Robertson, J.L. Occupancy distributions of membrane proteins in heterogeneous liposome populations. BBA Biomembranes, 2020, 1862(1), 183033. doi: 10.1016/j.bbamem.2019.183033
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