sulfo-Cyanine7 maleimide

Cat. # Quantity Price Lead time
15380 1 mg $115 in stock
25380 5 mg $295 in stock
45380 25 mg $790 in stock
55380 50 mg $1490 in stock
65380 100 mg $1990 in stock
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A reactive dye with a maleimide group for the labeling of thiol groups of proteins and other biomolecules, an analog of Cy7® maleimide.

sulfo-Cyanine7 is a hydrophilic near-infrared fluorophore with a rigidizing ring in its heptamethine chain that improves its photophysical properties. A great dye for various applications, including NIR imaging.

Sulfo-Cyanine7 maleimide absorbance and emission spectra

Sulfo-Cyanine7 maleimide absorbance and emission spectra

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General properties

Appearance: dark green powder
Mass spec M+ increment: 868.2
Molecular weight: 869.10
CAS number: 2183440-60-8 (potassium salt), 2183440-59-5 (inner salt)
Molecular formula: C43H49KN4O9S2
IUPAC name: 1-[2-(6-{2-[(E)-2-[(E)-3-{(E)-2-[1-Methyl-3,3-dimethyl-5-(oxysulfonyl)-2-indolinylidene]ethylidene}-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-5-(oxysulfonyl)-3H-indol-1-yl}hexanoylamino)ethyl]-1H-pyrrole-2,5-dione, potassium salt
Solubility: Good in water, DMF, DMSO. Low in non-polar organic solvents.
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04

Product citations

  1. Zhao, J.; Elgeti, M.; O’Brien, E.S.; Sár, C.P.; EI Daibani, A.; Heng, J.; Sun, X.; White, E.; Che, T.; Hubbell, W.L.; Kobilka, B.K.; Chen, C. Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature, 2024, 629(8011), 474-480. doi: 10.1038/s41586-024-07295-2
  2. Lee, J.; Kang, Y.K.; Oh, E.; Jeong, J.; Im, S.H.; Kim, D.K.; Lee, H.; Kim, S.-G.; Jung, K.; Chung, H.J. Nano-assembly of a Chemically Tailored Cas9 Ribonucleoprotein for In Vivo Gene Editing and Cancer Immunotherapy. Chemistry of Materials, 2022, 34(2), 547–561. doi: 10.1021/acs.chemmater.1c02844
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