Cyanine7 hydrazide
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
15070 | 1 mg | $125 | in stock | |
25070 | 5 mg | $260 | in stock | |
45070 | 25 mg | $510 | in stock | |
55070 | 50 mg | $895 | in stock | |
65070 | 100 mg | $1490 | in stock |
Hydrazide derivative of Cyanine7, a NIR fluorescent dye, an analog of Cy7®.
This variety of heptamethine fluorophore contains a six-membered ring rigidizing the polymethine chain which allows to increase quantum yield by 20% compared to parent structure.
Hydrazide reacts quickly and smoothly with aldehydes and ketones yielding stable hydrazone products. This reaction is also good for the labeling of glycoproteins after periodate oxidation.
Cyanine7 absorbance and emission spectra
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Activated ester for modification of proteins/antibodies/peptides followed by introduction into copper-free click chemistry reaction.General properties
Appearance: | green powder |
Mass spec M+ increment: | 544.8 |
Molecular weight: | 635.70 |
CAS number: | 2183440-61-9 (without anion) |
Molecular formula: | C37H48Cl2N4O |
Solubility: | moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols) |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 750 |
ε, L⋅mol−1⋅cm−1: | 199000 |
Emission maximum, nm: | 773 |
Fluorescence quantum yield: | 0.3 |
CF260: | 0.022 |
CF280: | 0.029 |
Product citations
- Shik, A. V.; Sobolev, P. V.; Zubritskaya, Y. V.; Baytler, M. O.; Stepanova, I. A.; Chernyaev, A. P.; Borschegovskaya, P. Yu.; Zolotov, S. A.; Doroshenko, I. A.; Podrugina, T. A.; Bliznyuk, U. A.; Rodin, I. A.; Beklemishev, M. K. Rapid Testing of Irradiation Dose in Beef and Potatoes by Reaction-Based Optical Sensing Technique. Journal of Food Composition and Analysis, 2024, 127, 105946. doi: 10.1016/j.jfca.2023.105946
- Pypin, A.A.; Shik, A.V.; Stepanova, I.A.; Doroshenko, I.A.; Podrugina, T.A.; Beklemishev, M.K. A Reaction-Based Optical Fingerprinting Strategy for the Recognition of Fat-Soluble Samples: Discrimination of Motor Oils. Sensors, 2023, 23(18), 7682. doi: 10.3390/s23187682
- Lix, K.; Krause, K.D.; Kim, H.; Algar, W.R. Investigation of the Energy Transfer Mechanism Between Semiconducting Polymer Dots and Organic Dyes. Journal of Physical Chemistry C, 2020, 124(31), 17387–17400. doi: 10.1021/acs.jpcc.0c04983
Cy® is a trademark of GE Healthcare.
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