TAMRA NHS ester, 6-isomer

Cat. # Quantity Price Lead time
18120 1 mg $110 in stock
28120 5 mg $210 in stock
48120 25 mg $350 in stock
58120 50 mg $595 in stock
68120 100 mg $790 in stock
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TAMRA (tetramethylrhodamine) is a xanthene dye with a fluorescence maximum at 567 nm.

This product is an N-Hydroxysuccinimide (NHS)-ester of TAMRA dye. Pure 6-isomer. TAMRA NHS-ester readily reacts with various amines and is used to generate fluorescently labeled proteins, peptides, antibodies, and other biomolecules.

Absorption and emission spectra of 6-TAMRA

Absorption and emission spectra of 6-TAMRA

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General properties

Appearance: red powder
Molecular weight: 527.53
CAS number: 150810-69-8
Molecular formula: C29H25N3O7
IUPAC name: 2-(6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl)-4-(((2,5-dioxopyrrolidin-1-yl)oxy)carbonyl)benzoate
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (90%)
Storage conditions: Storage: 12 months after receipt at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.34
CF280: 0.17

Product citations

  1. Wiesner, W.; Kühnel, R. M.; Pomorski, T. G. Synthesis and Purification of Lipid-Conjugated Fluorescent PH Sensors. Bio Protoc, 2023, 13(11), e4694. doi: 10.21769/BioProtoc.4694
  2. Dong, B.; Du, S.; Wang, C.; Fu, H.; Li, Q.; Xiao, N.; Yang, J.; Xue, X.; Cai, W.; Liu, D. Reversible Self-Assembly of Nanoprobes in Live Cells for Dynamic Intracellular pH Imaging. ACS Nano, 2019, 13(2), 1421–1432. doi: 10.1021/acsnano.8b07054
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