TAMRA NHS ester, 6-isomer
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 18120 | 1 mg |
$159.90
|
in stock | |
| 28120 | 5 mg |
$289.90
|
in stock | |
| 48120 | 25 mg |
$509.90
|
in stock | |
| 58120 | 50 mg |
$719.90
|
in stock | |
| 68120 | 100 mg |
$1150.00
|
in stock |
TAMRA (tetramethylrhodamine) is a xanthene dye with a fluorescence maximum at 567 nm.
This product is an N-Hydroxysuccinimide (NHS)-ester of TAMRA dye. Pure 6-isomer. TAMRA NHS-ester readily reacts with various amines and is used to generate fluorescently labeled proteins, peptides, antibodies, and other biomolecules.
Absorption and emission spectra of 6-TAMRA
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General properties
| Appearance: | red powder |
| Molecular weight: | 527.53 |
| CAS number: | 150810-69-8 |
| Molecular formula: | C29H25N3O7 |
| IUPAC name: | 2-(6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl)-4-(((2,5-dioxopyrrolidin-1-yl)oxy)carbonyl)benzoate |
| Solubility: | good in DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (90%) |
| Storage conditions: | Storage: 12 months after receipt at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 541 |
| ε, L⋅mol−1⋅cm−1: | 84000 |
| Emission maximum, nm: | 567 |
| Fluorescence quantum yield: | 0.1 |
| CF260: | 0.34 |
| CF280: | 0.17 |
Product citations
- Choi, J. E.; Yun, H.; Jeong, H.-J. Establishment of a Rapid and Convenient Fluoroimmunoassay Platform Using Antibodies Against PDL1 and HER2. Current Issues in Molecular Biology, 2025, 47(1), 62. doi: 10.3390/cimb47010062
- Deutsch-Williams, R. J.; Schleyer, K. A.; Das, R.; Carrothers, J. E.; Kohler, R. H.; Vinegoni, C.; Weissleder, R. FAP-Targeted Fluorescent Imaging Agents to Study Cancer-Associated Fibroblasts In Vivo. Bioconjugate Chem, 2025, 36(1), 44–53. doi: 10.1021/acs.bioconjchem.4c00426
- Wiesner, W.; Kühnel, R. M.; Pomorski, T. G. Synthesis and Purification of Lipid-Conjugated Fluorescent PH Sensors. Bio Protoc, 2023, 13(11), e4694. doi: 10.21769/BioProtoc.4694
- Dong, B.; Du, S.; Wang, C.; Fu, H.; Li, Q.; Xiao, N.; Yang, J.; Xue, X.; Cai, W.; Liu, D. Reversible Self-Assembly of Nanoprobes in Live Cells for Dynamic Intracellular pH Imaging. ACS Nano, 2019, 13(2), 1421–1432. doi: 10.1021/acsnano.8b07054
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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