Cyanine5.5 maleimide
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 17080 | 1 mg | $110.00 | in stock | |
| 27080 | 5 mg | $210.00 | in stock | |
| 47080 | 25 mg |
$410.00
|
in stock | |
| 57080 | 50 mg |
$695.00
|
in stock | |
| 67080 | 100 mg |
$1190.00
|
in stock |
Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5® maleimide.
Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications.
Cyanine5.5 can replace Cy5.5®, Alexa Fluor 680, and DyLight 680.
Cy5.5 absorbance and emission spectra
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Cyanine5.5 alkyne
Cyanine5.5 alkyne is a NIR (near infrared) dye azide for both copper-catalyzed, and copper-free Click Chemistry.Cyanine3 hydrazide
Cyanine3 hydrazide is a carbonyl-reactive dye for Cy3 channel.Sulfo-Cyanine5.5 carboxylic acid
Water soluble far red fluorescent dye sulfo-Cyanine5.5, free non-activated carboxylic acid. Useful for the calibration, and as a non-reactive control.General properties
| Appearance: | dark blue powder |
| Molecular weight: | 741.36 |
| CAS number: | 1593644-50-8 |
| Molecular formula: | C46H49ClN4O3 |
| IUPAC name: | 1H-Benz[e]indolium, 2-[5-[3-[6-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-6-oxohexyl]-1,3-dihydro-1,1-dimethyl-2H-benz[e]indol-2-ylidene]-1,3-pentadien-1-yl]-1,1,3-trimethyl- |
| Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L) |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 684 |
| ε, L⋅mol−1⋅cm−1: | 198000 |
| Emission maximum, nm: | 710 |
| Fluorescence quantum yield: | 0.2 |
| CF260: | 0.07 |
| CF280: | 0.03 |
Product citations
- Galstyan, A.; Chiechi, A.; Korman, A.J.; Sun, T.; Isreal, L.L.; Braubach, O.; Patil, R.; Shatalova, E.; Ljubimov, V.A.; Markman, J.; Grodzinski, Z.; Black, K.L.; Penichet, M.L.; Holler, E.; Ljubimov, A.V.; Ding, H.; Ljubimova, J.Y. Nano immunoconjugates crossing blood-brain barrier activate local brain tumor immune system for glioma treatment. bioRxiv, preprint. doi: 10.1101/466508
- Gardinier, T.C.; Turker, M.Z.; Hinckley, J.A.; Katt, W.P.; DomNwachukwu, N.; Woodruff, F.; Hersh, J.; Wang, J.; Cerione, R.A.; Wiesner, U.B. Controlling Surface Chemical Heterogeneities of Ultrasmall Fluorescent Core–Shell Silica Nanoparticles as Revealed by High-Performance Liquid Chromatography. The Journal of Physical Chemistry C, 2019, 123(37), 23246–23254. doi: 10.1021/acs.jpcc.9b06905
- Chen, C.; Corry, B.; Huang, L.; Hildebrandt, N. FRET-modulated multi-hybrid nanoparticles for brightness-equalized single-wavelength barcoding. Journal of the American Chemical Society, 2019, 141(28), 11123–11141. doi: 10.1021/jacs.9b03383
- Guo, S.; Xiao, X.; Wang, X.; Luo, Q.; Zhu, H.; Zhang, H.; Li, H.; Gong, Q.; Luo, K. Reductive microenvironment responsive gadolinium-based polymers as potential safe MRI contrast agents. Biomaterials Science, 2019, 7(5), 1919–1932. doi: 10.1039/c8bm01103f
Cy® is a trademark of GE Healthcare.
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