Cyanine7.5 azide
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 46030 | 1 mL, 10 mM in DMSO |
$410.00
|
in stock | |
| 16030 | 100 uL, 10 mM/DMSO | $110.00 | in stock | |
| 36030 | 500 uL, 10 mM/DMSO | $210.00 | in stock | |
| A6030 | 1 mg | $110.00 | in stock | |
| B6030 | 5 mg | $210.00 | in stock | |
| C6030 | 10 mg | $310.00 | in stock | |
| D6030 | 25 mg |
$410.00
|
in stock | |
| E6030 | 50 mg |
$695.00
|
in stock | |
| F6030 | 100 mg |
$1190.00
|
in stock |
Cyanine7.5 is a NIR dye with long-wave infrared fluorescence. This derivative is azide for Click Chemistry.
Can be used for the construction of various labeled biomolecules containing Cyanine7.5, near infrared fluorescent dye, and an improved analog of Cy7.5®. These conjugates can take advantage of NIR tissue transparency when used for in vivo imaging. This fluorophore is also useful for other fluorescent applications, especially requiring low fluorescent background.
Azide is available as DMSO solution, ready for general Click Chemistry labeling protocol, or in solid form for custom labeling applications.
Structure features rigid bridged polymethyne chain to increase quantum yield by 20%, allowing for brighter signal.
Cyanine7.5 absorbance and emission spectra
Recommended protocol
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General properties
| Appearance: | green powder / solution |
| Molecular weight: | 767.44 |
| Molecular formula: | C48H55ClN6O |
| Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation maximum, nm: | 788 |
| ε, L⋅mol−1⋅cm−1: | 223000 |
| Emission maximum, nm: | 808 |
Product citations
- Kong, J.-N.; Zhu, Z.; Itokazu, Y.; Wang, G.; Dinkins, M.B.; Zhong, L.; Lin, H.-P.; Elsherbini, A.; Leanhart, S.; Jiang, X.; Qin, H.; Zhi, W.; Spassieva, S.D.; Bieberich, E. Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes. Journal of Lipid Research, 2018, 59(3), 488–506. doi: 10.1194/jlr.M081877
- van der Steen, S.C.H.A.; Raavé, R.; Langerak, S.; van Houdt, L.; van Duijnhoven, S.M.J.; van Lith, S.A.M.; Massuger, L.F.A.G.; Daamen, W.F.; Leenders, W.P.; van Kuppevelt, T.H. Targeting the extracellular matrix of ovarian cancer using functionalized, drug loaded lyophilisomes. European Journal of Pharmaceutics and Biopharmaceutics, 2017, 113, 229–239. doi: 10.1016/j.ejpb.2016.12.010
- Junker, M.; Rapoport, T.A. Involvement of VAT-1 in phosphatidylserine transfer from the endoplasmic reticulum to mitochondria. Traffic, 2015, 16(12), 1306–1317. doi: 10.1111/tra.12336
Cy® is a trademark of GE Healthcare.
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