Sulfo-Cyanine3 azide

Cat. # Quantity Price Lead time
A1330 1 mg $110.00 in stock
B1330 5 mg $290.00 in stock
C1330 10 mg $470.00 in stock
D1330 25 mg $690.00 in stock
E1330 50 mg $1270.00 in stock
F1330 100 mg $1990.00 in stock

Sulfo-Cyanine3 azide is a water-soluble dye azide for Click Chemistry. Absorbance and emission of the dye are identical to Cy3® fluorophore.

Brightness and photostability of fluorophore, together with high water solubility, makes this reagent an ideal choice for Click chemistry labeling of various molecules in aqueous phase.

Click reaction can be carried out in pure water without need to use organic co-solvent. The reagent is designed for the labeling of sensitive molecules such as proteins, and even intact biological objects.

Sulfo-Cyanine3 absorbance and emission spectra

Sulfo-Cyanine3 absorbance and emission spectra

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General properties

Appearance: dark red crystals
Molecular weight: 736.94
CAS number: 2055138-89-9 (sodium salt), 1658416-54-6
Molecular formula: C33H41N6KO7S2
Solubility: soluble in water (0.62 M = 46 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

Product citations

  1. Wells, C.I.; Al-Ali, H.; Andrews, D.M.; Asquith, C.R.M.; Axtman, A.D.; Chung, M.; Dikic, I.; Ebner, D.; Elkins, J.M.; Ettmayer, P.; Fischer, C.; Frederiksen, M.; Gray, N.S.; Hatch, S.; Knapp, S.; Lee, S.; Lücking, U.; Michaelides, M.; Mills, C.E.; Müller, S.; Owen, D.; Picado, A.; Ramadan, K.; Saikatendu, K.S.; Schröder, M.; Stolz, A.; Tellechea, M.; Treiber, D.K.; Turunen, B.J.; Vilar, S.; Wang, J.; Zuercher, W.J.; Willson, T.M.; Drewry, D.H. The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification. bioRxiv, preprint. doi: 10.1101/2019.12.22.886523
  2. Wang, J.; Li, T.; Wang, J.-L.; Xu, Z.; Meng, W.; Wu, Q.-F. Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Reports, 2020, 33(11), 108495. doi: 10.1016/j.celrep.2020.108495
  3. Zahnreich, S.; Weber, B.; Rösch, G.; Schindler, D.; Schmidberger, H. Compromised repair of radiation-induced DNA double-strand breaks in Fanconi anemia fibroblasts in G2. DNA Repair, 2020, 96, 102992. doi: 10.1016/j.dnarep.2020.102992
  4. Agote-Aran, A.; Schmucker, S.; Jerabkova, K.; Jmel Boyer, I.; Berto, A.; Pacini, L.; Ronchi, P.; Kleiss, C.; Guerard, L.; Schwab, Y.; Moine, H.; Mandel, J.-L.; Jacquemont, S.; Bagni, C.; Sumara, I. Spatial control of nucleoporin condensation by fragile X-related proteins. EMBO Journal, 2020, 39(20), e104467. doi: 10.15252/embj.2020104467
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