Azidobutyric acid NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 53720 | 50 mg | $60.00 | in stock | |
| 63720 | 100 mg | $95.00 | in stock | |
| 73720 | 1 g |
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|
in stock | |
| 83720 | 5 g |
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|
in stock |
Convert your proteins and peptides into Click Chemistry reactive form with this reagent.
While Click Chemistry involves reaction between terminal alkyne and azide, both azides and alkynes are very uncommon in nature. However, there are reagents to attach these fragments to abundant amino groups which are ubiquitous in the world of biomolecules. This azido-NHS ester is designed for the conversion of proteins, peptides, amino-DNA, and other amines into Click Chemistry reactive azides.
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AmdU (5-azidomethyl-2'-deoxyuridine)
Azidomethyldeoxyuridine (AmdU) is an azide containing nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain promoted Click chemistry.Sulfo-Cyanine3 maleimide
Water soluble thiol-reactive derivative of Sulfo-Cyanine3, a Cy3® analog.General properties
| Appearance: | colorless solid |
| Mass spec M+ increment: | 111.0 |
| Molecular weight: | 226.19 |
| CAS number: | 943858-70-6 |
| Molecular formula: | C8H10N4O4 |
| IUPAC name: | Butanoic acid, 4-azido-, 2,5-dioxo-1-pyrrolidinyl ester |
| Solubility: | soluble in organic solvents (DMF, DMSO) |
| Quality control: | NMR 1H (95%), HPLC |
| Storage conditions: | Storage: 12 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Product citations
- Wang, Y.; Yao, J.; Cai, L.; Liu, T.; Wang, X.; Zhang, Y.; Zhou, Z.; Li, T.; Liu, M.; Lai, R.; Liu, X. Bone-targeted extracellular vesicles from mesenchymal stem cells for osteoporosis therapy. Research Square, preprint. doi: 10.21203/rs.3.rs-18279/v1
- Kleinpenning, F.; Steigenberger, B.; Wu, W.; Heck, A.J.R. Fishing for newly synthesized proteins with phosphonate-handles. Nature Communications, 2020, 11, 3244. doi: 10.1038/s41467-020-17010-0
- Blanchard, A.T.; Bazrafshan, A.S.; Yi, J.; Eisman, J.T.; Yehl, K.M.; Bian, T.; Mugler, A.; Salaita, K. Highly Polyvalent DNA Motors Generate 100+ pN of Force via Autochemophoresis. Nano Letters, 2019, 19(10), 6977–6986. doi: 10.1021/acs.nanolett.9b02311
- Hou, W.; Li, Y.; Kang, W.; Wang, X.; Wu, X.; Wang, S.; Liu, F. Real-time analysis of quantum dot labeled single porcine epidemic diarrhea virus moving along the microtubules using single particle tracking. Scientific Reports, 2019, 9, 1307. doi: 10.1038/s41598-018-37789-9
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