Azidobutyric acid NHS ester

Cat. # Quantity Price Lead time
53720 50 mg $110 in stock
63720 100 mg $210 in stock
73720 1 g $950 in stock
83720 5 g please inquire in stock
Found better price? Let us know and we will propose the way forward!

Convert your proteins and peptides into click chemistry reactive form with this reagent.

While click chemistry involves reaction between terminal alkyne and azide, both azides and alkynes are very uncommon in nature. However, there are reagents to attach these fragments to abundant amino groups which are ubiquitous in the world of biomolecules. This azido-NHS ester is designed for the conversion of proteins, peptides, amino-DNA, and other amines into click chemistry reactive azides.

Customers also purchased with this product

Cyanine5.5 carboxylic acid

Cy5.5 unactivated free acid cyanine dye.

sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

THPTA ligand

THPTA is a water-soluble ligand for Cu(I)-catalyzed click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.

General properties

Appearance: colorless solid
Mass spec M+ increment: 111.0
Molecular weight: 226.19
CAS number: 943858-70-6
Molecular formula: C8H10N4O4
IUPAC name: Butanoic acid, 4-​azido-​, 2,​5-​dioxo-​1-​pyrrolidinyl ester
Solubility: soluble in organic solvents (DMF, DMSO)
Quality control: NMR 1H (95%), HPLC
Storage conditions: Storage: 12 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Product citations

  1. Afting, C.; Walther, T.; Wittbrodt, J.; Göpfrich, K. DNA microbeads for spatio-temporally controlled morphogen release within organoids. bioRxiv, 2024, preprint. doi: 10.1101/2024.01.10.575045
  2. Osuofa, J.; Husson, S.M. Preparation of Protein A Membranes Using Propargyl Methacrylate-Based Copolymers and Copper-Catalyzed Alkyne–Azide Click Chemistry. Polymers, 2024, 16(2), 239. doi: 10.3390/polym16020239
  3. Skardžiūtė, K.; Kvederavičiūtė, K.; Pečiulienė, I.; Narmontė, M.; Gibas, P.; Ličytė, J.; Klimašauskas, S.; Kriukienė, E. One-pot trimodal mapping of unmethylated, hydroxymethylated, and open chromatin sites unveils distinctive 5hmC roles at dynamic chromatin loci. Cell Chemical Biology, 2024, 31(3), 607-621.e9. doi: 10.1016/j.chembiol.2023.12.003
  4. Sim, J.; Li, M.; Park, K. M.; Kim, K. Identification of Mitochondrial Proteins Associated with Cyanine 5 Using a Combination of Affinity-Based Photocrosslinking with Bio-Orthogonal Supramolecular Latching. J. Porphyrins Phthalocyanines, 2023, 27(07n10), 1148–1155. doi: 10.1142/S108842462350058X
Show more (16)
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.