Amino-11-ddUTP

Cat. # Quantity Price Lead time
A5040 200 nmol $190.00 in stock
15040 1 umol $549.00 in stock
25040 5 umol $1590.00 5 days
45040 25 umol $3975.00 5 days

Amino-11-ddUTP is a terminator triphosphate for enzymatic end-labeling of DNA. The nucleotide is incorporated by Taq DNA polymerase, Sequenase, Klenow fragment. Subsequent reaction of amino-terminated DNA with activated esters can be used for the end-labeling of DNA.

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General properties

Appearance: colorless solid
Molecular weight: 960.44
CAS number: 439077-17-5 (without cation and water of crystallization)
Molecular formula: C18H62Li3N4O32P3
Solubility: good in water
Quality control: NMR 1H and 31P, HPLC-MS (99+%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Product citations

  1. Bakker, R.; Mani, M.; Carthew, R.W. The Wg and Dpp morphogens regulate gene expression by modulating the frequency of transcriptional bursts. bioRxiv, preprint. doi: 10.1101/2020.01.24.918623
  2. Boersma, S.; Rabouw, H.H.; Bruurs, L.J.M.; Pavlovič, T.; van Vliet, A.L.W.; Beumer, J.; Clevers, H.; van Kuppeveld, F.J.M.; Tanenbaum, M.E. Translation and Replication Dynamics of Single RNA Viruses. Cell, 2020, 183(7), 1930–1945.e23. doi: 10.1016/j.cell.2020.10.019
  3. Yu, Y.; Guo, Y.; Tian, Q.; Lan, Y.; Yeh, H.; Zhang, M.; Tasan, I.; Jain, S.; Zhao, H. An efficient gene knock-in strategy using 5'-modified double-stranded DNA donors with short homology arms. Nature Chemical Biology, 2020, 16(4), 387–390. doi: 10.1038/s41589-019-0432-1
  4. Hampoelz, B.; Schwarz, A.; Ronchi, P.; Bragulat-Teixidor, H.; Tischer, C.; Gaspar, I.; Ephrussi, A.; Schwab, Y.; Beck, M. Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis. Cell, 2019, 179, 671–686.e17. doi: 10.1016/j.cell.2019.09.022
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