sulfo-Cyanine5 alkyne
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A33B0 | 1 mg | $125 | in stock | |
| B33B0 | 5 mg | $290 | in stock | |
| C33B0 | 10 mg |
$470
|
in stock | |
| D33B0 | 25 mg |
$850
|
in stock | |
| E33B0 | 50 mg |
$1490
|
in stock | |
| F33B0 | 100 mg |
$1990
|
in stock |
Water soluble reagent with alkyne group for click chemistry. Sulfo-Cyanine5 is a sulfonated dye with high hydrophilicity and aqueous solubility, exceptionally high extinction coefficient, good quantum yield, and compatibility with many instruments.
This reagent is recommended for the conjugation with proteins, nanoparticles, and other applications where hydrophilicity is important.
Absorbance and emission spectra of sulfo-Cyanine5
Recommended protocol
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Alkyne-PEG4-maleimide
Water soluble, heterobifunctional hydrophilic linker with a length of 14 Å, containing maleimide for thiol labeling, and alkyne for click chemistry. An ideal reagent to attach an alkyne moiety to a protein.AF 488 azide
AF 488 azide is a fluorophore with emission in the green spectrum range. It reacts with alkynes in copper-catalyzed cycloaddition reactions.Copper(II)-TВTA catalytic buffer, 1.5x
Ready-to-use catalytic buffer containing сopper(II) and TBTA ligand. It is suitable for click chemistry modification of nucleic acids and small molecules.General properties
| Appearance: | dark blue solid |
| Molecular weight: | 717.94 |
| CAS number: | 1617572-09-4 (inner salt); 1617497-19-4 (sodium salt) |
| Molecular formula: | C35H40N3KO7S2 |
| Solubility: | very high in water, DMSO, DMF |
| Quality control: | NMR 1H, HPLC-MS (95+%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 646 |
| ε, L⋅mol−1⋅cm−1: | 271000 |
| Emission maximum, nm: | 662 |
| Fluorescence quantum yield: | 0.28 |
| CF260: | 0.04 |
| CF280: | 0.04 |
Product citations
- Yoshikawa, A. M.; Rangel, A. E.; Zheng, L.; Wan, L.; Hein, L. A.; Hariri, A. A.; Eisenstein, M.; Soh, H. T. A Massively Parallel Screening Platform for Converting Aptamers into Molecular Switches. Nat Commun, 2023, 14(1), 2336. doi: 10.1038/s41467-023-38105-4
- Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Scientific Reports, 2021, 11(1), 12229. doi: 10.1038/s41598-021-91612-6.
- Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a "multiple gear" regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
- Guarin, M.; Ny, A.; De Croze, N.; Maes, J.; Léonard, M.; Annaert, P.; de Witte, P. A. M. Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis. Pharmaceuticals, 2021, 14(6), 576. doi: 10.3390/ph14060576
Cy® is a trademark of GE Healthcare.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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