Sulfo-Cyanine5 alkyne

sulfo-Cyanine5 Alkynes Microscopy
Cat. # Quantity Price Lead time
A33B0 1 mg $110.00 in stock
B33B0 5 mg $290.00 in stock
C33B0 10 mg $470.00 in stock
D33B0 25 mg $690.00 in stock
E33B0 50 mg $1270.00 in stock
F33B0 100 mg $1990.00 in stock
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Water soluble reagent with alkyne group for Click Chemistry. Sulfo-Cyanine5 is a sulfonated dye, which possesses high hydrophilicity and aqueous solubility, exceptionally high extinction coefficient, good quantum yield, and compatibility with many instruments.

This reagent is recommended for the conjugation with proteins, nanoparticles, and other applications where hydrophilicity is important.

Structure of Sulfo-Cyanine3.5 NHS ester dye
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Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 absorbance and emission spectra

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DMSO, labeling grade

Pure dimethyl sulfoxide (DMSO) solvent with quality optimised for Click and other cojugation reactions

Cyanine3 alkyne

Cyanine3 alkyne is a fluorescent dye alkyne for Click Chemistry.

Sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

General properties

Appearance: dark blue solid
Molecular weight: 717.94
CAS number: 1617572-09-4 (inner salt); 1617497-19-4 (sodium salt)
Molecular formula: C35H40N3KO7S2
Solubility: very high in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

Product citations

  1. Zhou, L.; Wu, Y.; Luo, Y.; Li, H.; Meng, X.; Liu, Cl; Xiang, J.; Zhang, P.; Gong, P.; Cai, L. Mitochondria-localized Self-reporting Small Molecule Decorated Theranostic Agents for Cancer-organelle Transporting and Imaging. ACS Applied Bio Materials, 2019, 2(11), 5164–5173. doi: 10.1021/acsabm.9b00811
  2. Gao, F.; Hunter, A.; Qu, S.; Hoffman, J.R.; Gao, P.; Phillip, W.A. Interfacial Junctions Control Electrolyte Transport Through Charge-Patterned Membranes. ACS Nano, 2019, 13(7), 7655–7664. doi: 10.1021/acsnano.9b00780
  3. Rojas-Sánchez, L.; Sokolova, V.; Riebe, S.; Voskuhl, J.; Epple, M. Covalent Surface Functionalization of Calcium Phosphate Nanoparticles with Fluorescent Dyes by Copper-Catalysed and by Strain-Promoted Azide-Alkyne Click Chemistry. ChemNanoMat, 2019, 5(4), 436–446. doi: 10.1002/cnma.201800509
  4. Braselmann, E.; Wierzba, A.J.; Polaski, J.T.; Chromiński, M.; Holmes, Z.E.; Hung, S.-T.; Batan, D.; Wheeler, J.R.; Parker, R.; Jimenez, R.; Gryko, D.; Batey, R.T.; Palmer, A.E. A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells. Nature Chemical Biology, 2018, 14(10), 964–971. doi: 10.1038/s41589-018-0103-7
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