Biotin-PEG3-azide

Cat. # Quantity Price Lead time
C3730 10 mg $125 in stock
D3730 25 mg $220 in stock
E3730 50 mg $325 in stock
F3730 100 mg $450 in stock
K3730 1 g $1420 in stock
Found better price? Let us know and we will propose the way forward!

Biotin-PEG3-azide is a click chemistry biotinylation tool. This reagent allows the labeling of alkynylated molecules (such as DNA, oligonucleotides, and proteins) with biotin via copper-catalyzed or copper-free click reaction. Biotin-labeled biomolecules can be bound to avidin or streptavidin for further purification and detection.

This structure of biotin azide features a long hydrophilic PEG3 linker that separates biotin residue from the target molecule for efficient binding with streptavidin. Its linker also enhances aqueous solubility to facilitate conjugation.

The azide can be conjugated with various molecules using our recommended protocol.

Customers also purchased with this product

Cyanine5 amine

Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.
Add this product to your cart and
get free express delivery

sulfo-Cyanine5 alkyne

sulfo-Cyanine5 is a water-soluble Cyanine5 dye alkyne for click chemistry.

sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

General properties

Appearance: colorless solid
Molecular weight: 400.50
CAS number: 1910803-72-3
Molecular formula: C16H28N6O4S
Solubility: soluble in DMF, DMSO, moderately soluble in water
Quality control: NMR 1H (95%) and 13C, TLC, functional testing
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications

Product citations

  1. Liang, J.; Han, J.; Gao, X.; Jia, H.; Li, R.; Tse, E. C. M.; Li, Y. Clickable APEX2 Probes for Enhanced RNA Proximity Labeling in Live Cells. Anal. Chem., 2024, 96(2), 685–693. doi: 10.1021/acs.analchem.3c03614
  2. Edr, A.; Wrobel, D.; Krupková, A.; Šťastná, L. Č.; Cuřínová, P.; Novák, A.; Malý, J.; Kalasová, J.; Malý, J.; Malý, M.; Strašák, T. Adaptive Synthesis of Functional Amphiphilic Dendrons as a Novel Approach to Artificial Supramolecular Objects. International Journal of Molecular Sciences, 2022, 23(4), 2114. doi: 10.3390/ijms23042114
  3. Shen, J.Z.; Qiu, Z.; Wu, Q.; Finlay, D.; Garcia, G.; Sun, D.; Rantala, J.; Barshop, W.; Hope, J.L.; Gimple, R.C.; Sangfelt, O.; Bradley, L.M.; Wohlschlegel, J.; Rich, J.N.; Spruck, C. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell, 2021, 184(2), 352–369.e23. doi: 10.1016/j.cell.2020.11.042
  4. Zeng, Q.; Deng, H.; Li, Y.; Fan, T.; Liu, Y.; Tang, S.; Wei, W.; Liu, X.; Guo, X.; Jiang, J.; Wang, Y.; Song, D. Berberine Directly Targets the NEK7 Protein to Block the NEK7–NLRP3 Interaction and Exert Anti-inflammatory Activity. Journal of Medicinal Chemistry, 2021, 64(1), 768–781. doi: 10.1021/acs.jmedchem.0c01743
Show more (5)
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.