DBCO NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 34720 | 10 mg | $80.00 | in stock | |
| 44720 | 25 mg | $110.00 | in stock | |
| 54720 | 50 mg | $135.00 | in stock | |
| 64720 | 100 mg | $210.00 | in stock | |
| 94720 | 1 g |
$1000.00
|
in stock | |
| K4720 | 5 g |
$3570.00
|
in stock |
Dibenzocyclooctyne (ADIBO, DBCO) is one of the most reactive cycloalkynes for strain-promoted alkyne azide cycloaddition (SPAAC) – a copper-free click chemistry reaction.
DBCO reacts instantly with azides. The reaction rate is much higher than that of copper-catalyzed reaction, and reactions with many other cyclooctynes. Unlike some other cyclooctynes, DBCO does not react with tetrazines - this allows to carry out orthogonal conjugation of azides with DBCO, and trans-cyclooctenes with tetrazines.
This amine-reactive NHS ester provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as protein, peptide, or small molecule amine.
Customers also purchased with this product
BDP R6G azide
BDP R6G is a high performance borondipyrromethene fluorophore which is tuned to match excitation and emission channels of R6G dye.sulfo-Cyanine7.5 alkyne
sulfo-Cyanine7.5 is a near-infrared fluorophore similar to Indocyanine Green (ICG) but possesses higher fluorescence quantum yield. This is an alkyne for copper-catalyzed click chemistry.BDP TMR maleimide
A bright, thiol reactive dye for TAMRA channel. Useful for microscopy and fluorescence polarization assays, among other applications.
Add this product to your cart andget free express delivery
General properties
| Appearance: | off white solid |
| Mass spec M+ increment: | 315.1 |
| Molecular weight: | 430.45 |
| CAS number: | 1384870-47-6 |
| Molecular formula: | C25H22N2O5 |
| IUPAC name: | 6-{2-Azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-6-oxohexanamide |
| Solubility: | good in DCM, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Product citations
- Gabold, B.; Adams, F.; Brameyer, S.; Jung, K.; Ried, C. L.; Merdan, T.; Merkel, O. M. Transferrin-Modified Chitosan Nanoparticles for Targeted Nose-to-Brain Delivery of Proteins. Drug Deliv. and Transl. Res., 2023, 13(3), 822–838. doi: 10.1007/s13346-022-01245-z
- Edr, A.; Wrobel, D.; Krupková, A.; Šťastná, L. Č.; Cuřínová, P.; Novák, A.; Malý, J.; Kalasová, J.; Malý, J.; Malý, M.; Strašák, T. Adaptive Synthesis of Functional Amphiphilic Dendrons as a Novel Approach to Artificial Supramolecular Objects. International Journal of Molecular Sciences, 2022, 23(4), 2114. doi: 10.3390/ijms23042114
- Jo, M. H.; Li, J.; Jaumouillé, V.; Hao, Y.; Coppola, J.; Yan, J.; Waterman, C. M.; Springer, T. A.; Ha, T. Single-Molecule Characterization of Subtype-Specific Β1 Integrin Mechanics. Nature Communications, 2022, 13(1), 7471. doi: 10.1038/s41467-022-35173-w
- Adams, M.R.; Moody, C.T.; Sollinger, J.L.; Brudno, Y. Extracellular Matrix-Anchored Click Motifs for Specific Tissue Targeting. Molecular Pharmaceutics, 2020, 17(2), 392–403. doi: 10.1021/acs.molpharmaceut.9b00589
The count of items is incorrect.
Your cart is empty
$ 
