Cyanine7.5 carboxylic acid

Cyanine7.5 Carboxylic acids Near infrared (NIR) imaging

Cat. #	Quantity	Price	Lead time
16090	1 mg	$125	in stock
26090	5 mg	$260	in stock
46090	25 mg	$510	in stock
56090	50 mg	$895	in stock
66090	100 mg	$1490	in stock

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Free unactivated Cyanine7.5 NIR dye carboxylic acid.

For coupling and labeling reactions also consider using pre-activated Cyanine7.5 NHS ester.

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Cy7.5 absorbance and emission spectra

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Pentynoic acid STP ester

An activated ester for the introduction of alkyne into peptides/proteins and click reaction.

This molecule is a conjugate of bright fluorophore FAM (fluorescein) and tetrazine, a reactive group that reacts with trans-cycloalkenes in a reaction called IEDDA (inverse electron demand Diels-Alder reaction).

Cyanine7.5 alkyne

Reactive near infrared (NIR) dye for click chemistry containing a terminal alkyne group.

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General properties

Appearance:	green powder
Molecular weight:	685.34
CAS number:	1803099-44-6
Molecular formula:	C₄₅H₄₉ClN₂O₂
Solubility:	soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	788
ε, L⋅mol⁻¹⋅cm⁻¹:	223000
Emission maximum, nm:	808
Fluorescence quantum yield:	0.10

Product citations

Xu, S.; Zhang, P.; Heing-Becker, I.; Zhang, J.; Tang, P.; Bej, R.; Bhatia, S.; Zhong, Y.; Haag, R. Dual Tumor- and Subcellular-Targeted Photodynamic Therapy Using Glucose-Functionalized MoS2 Nanoflakes for Multidrug-Resistant Tumor Ablation. Biomaterials, 2022, 290, 121844. doi: 10.1016/j.biomaterials.2022.121844
Almeida, A.; Castro, F.; Resende, C.; Lúcio, M.; Schwartz, S.; Sarmento, B. Oral Delivery of Camptothecin-Loaded Multifunctional Chitosan-Based Micelles Is Effective in Reduce Colorectal Cancer. Journal of Controlled Release, 2022, 349, 731–743. doi: 10.1016/j.jconrel.2022.07.029
Nie, T.; He, Z.; Zhu, J.; Chen, K.; Howard, G.P.; Pacheco-Torres, J.; Minn, I.; Zhao, P.; Bhujwalla, Z.M.; Mao, H.-Q.; Liu, L.; Chen, Y. Non-invasive delivery of levodopa-loaded nanoparticles to the brain via lymphatic vasculature to enhance treatment of Parkinson's disease. Nano Research, 2021, 14(8), 2749–2761. doi: 10.1007/s12274-020-3280-0
Amar-Lewis, E.; Buaron, N.; Chintakunta, R.; Benafsha, C.; Goldbart, R.; Traitel, T.; Prasad, M.; Elkabets, M.; Kost, J. Quaternized Starch-Based Composite Nanoparticles for siRNA Delivery to Tumors. ACS Applied Nano Materials, 2021, 4(2), 2218–2229. doi: 10.1021/acsanm.1c00032

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Cy® is a trademark of GE Healthcare.

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.