EdU (5-ethynyl-2'-deoxyuridine)

Cat. # Quantity Price Lead time
10540 100 mg $120.00 in stock
20540 250 mg $195.00 in stock
30540 500 mg $345.00 in stock
40540 1 g $590.00 in stock

EdU (ethynyldeoxyuridine) is a nucleoside, an analog of thymidine, carrying an ethynyl group. This nucleoside behaves as a substrate for cellular DNA replication machinery. Then, DNA containing ethynyl groups can be developed by Click chemistry reaction with various dye azides. Fluorescent DNA can be detected by microscopy, or cells can be sorted by FACS.

Customers also purchased with this product

BDP 558/568 NHS ester

BDP 558/568 is a fluorophore for the yellow region of the spectrum. Like other BDP dyes, this fluorophore has high fluorescence quantum yield, brightness, and photostability.

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

Cyanine5 carboxylic acid

Cyanine5 carboxylic acid, unactivated dye.

General properties

Appearance: light beige to light brown solid
Molecular weight: 252.22
CAS number: 61135-33-9
Molecular formula: C11H12N2O5
Solubility: good in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications

Product citations

  1. Lyu, X.; Lei, K.-H.; Biak Sang, P.; Shiva, O.; Chastain, M.; Chi, P.; Chai, W. Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA. EMBO Journal, in press. doi: 10.15252/embj.2019103654
  2. Wells, C.I.; Al-Ali, H.; Andrews, D.M.; Asquith, C.R.M.; Axtman, A.D.; Chung, M.; Dikic, I.; Ebner, D.; Elkins, J.M.; Ettmayer, P.; Fischer, C.; Frederiksen, M.; Gray, N.S.; Hatch, S.; Knapp, S.; Lee, S.; Lücking, U.; Michaelides, M.; Mills, C.E.; Müller, S.; Owen, D.; Picado, A.; Ramadan, K.; Saikatendu, K.S.; Schröder, M.; Stolz, A.; Tellechea, M.; Treiber, D.K.; Turunen, B.J.; Vilar, S.; Wang, J.; Zuercher, W.J.; Willson, T.M.; Drewry, D.H. The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification. bioRxiv, preprint. doi: 10.1101/2019.12.22.886523
  3. Irwin, N.A.T.; Pittis, A.A.; Mathur, V.; Howe, L.J.; Keeling, P.J.; Lynn, D.H.; Bourland, W.A. The Function and Evolution of Motile DNA Replication Systems in Ciliates. Current Biology, 2021, 31(1), 66–76.e6. doi: 10.1016/j.cub.2020.09.077
  4. Wang, Z.; Cui, M.; Shah, A.M.; Tan, W.; Liu, N.; Bassel-Duby, R.; Olson, E.N. Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution. Cell Reports, 2020, 33(10), 108472. doi: 10.1016/j.celrep.2020.108472
Show more (14)
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.