EdU (5-ethynyl-2'-deoxyuridine)

Cat. # Quantity Price Lead time
10540 100 mg $120.00 in stock
20540 250 mg $195.00 in stock
30540 500 mg $345.00 in stock
40540 1 g $590.00 10 days

EdU (ethynyldeoxyuridine) is a nucleoside, an analog of thymidine, carrying an ethynyl group. This nucleoside behaves as a substrate for cellular DNA replication machinery. Then, DNA containing ethynyl groups can be developed by Click chemistry reaction with various dye azides. Fluorescent DNA can be detected by microscopy, or cells can be sorted by FACS.

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Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

Pico488 dsDNA quantification reagent, 200x solution in DMSO

Pico488 is a dye for precise fluorescence based quantification of dsDNA in the presence of RNA, ssDNA, and other impurities. The dye exhibits bright fluorescence in the fluorescein channel, which provides a linear response to DNA concentration within the range of low pg/mL to high ng/mL.

BDP 630/650 alkyne

Alkyne dye for copper catalyzed Click chemistry, containing borondipyrromethene fluorophore BDP 630/650 for red channel.

General properties

Appearance: light beige to light brown solid
Molecular weight: 252.22
CAS number: 61135-33-9
Molecular formula: C11H12N2O5
Solubility: good in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications

Product citations

  1. Wells, C.I.; Al-Ali, H.; Andrews, D.M.; Asquith, C.R.M.; Axtman, A.D.; Chung, M.; Dikic, I.; Ebner, D.; Elkins, J.M.; Ettmayer, P.; Fischer, C.; Frederiksen, M.; Gray, N.S.; Hatch, S.; Knapp, S.; Lee, S.; Lücking, U.; Michaelides, M.; Mills, C.E.; Müller, S.; Owen, D.; Picado, A.; Ramadan, K.; Saikatendu, K.S.; Schröder, M.; Stolz, A.; Tellechea, M.; Treiber, D.K.; Turunen, B.J.; Vilar, S.; Wang, J.; Zuercher, W.J.; Willson, T.M.; Drewry, D.H. The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification. bioRxiv, preprint. doi: 10.1101/2019.12.22.886523
  2. Gerosa, L.; Chidley, C.; Froehlich, F.; Sanchez, G.; Lim, S.K.; Muhlich, J.; Chen, J.-Y.; Baker, G.J.; Schapiro, D.; Shi, T.; Yi, L.; Nicora, C.D.; Claas, A.; Lauffenburger, D.A.; Qian, W.-J.; Wiley, H.S.; Sorger, P.K. Sporadic ERK pulses drive non-genetic resistance in drug-adapted BRAFV600E melanoma cells. bioRxiv, preprint. doi: 10.1101/762294
  3. Shunatova, N.; Borisenko, I. Proliferating activity in a bryozoan lophophore. PeerJ, 2020, 8, e9179. doi: 10.7717/peerj.9179
  4. Wang, S.P.; Cao, S.; Arhatte, M.; Li, D.; Shi, Y.; Kurz, S.; Hu, J.; Wang, L.; Shao, J.; Atzberger, A.; Wang, Z.; Wang, C.; Zang, W.; Fleming, I.; Wettschureck, N:, Honoré, E.; Offermanns, S. Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice. Nature Communications, 2020, 11, 2303. doi: 10.1038/s41467-020-16026-w
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