EdU (5-Ethynyl-2'-deoxyuridine)

Cat. # Quantity Price Lead time
A0540 5 mg –   in stock
10540 100 mg $120.00 in stock
20540 250 mg $195.00 in stock
30540 500 mg $345.00 in stock
40540 1 g $590.00 in stock
60540 5 g please inquire in stock

EdU (5-ethynyl-2’-deoxyuridine) is a nucleoside, an analog of thymidine, carrying an ethynyl group. This nucleoside behaves as a substrate for cellular DNA replication machinery. After EdU incorporation, DNA containing ethynyl groups can be ligated by click chemistry reaction with various dye azides. Fluorescent DNA can be detected with microscopy, or cells can be sorted with FACS.

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Cyanine5 azide

Cyanine5 azide is a reagent for click chemistry labeling with Cyanine5, a popular fluorescent dye.
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Cyanine5 carboxylic acid

Cyanine5 carboxylic acid, unactivated dye.

General properties

Appearance: light beige to light brown solid
Molecular weight: 252.22
CAS number: 61135-33-9
Molecular formula: C11H12N2O5
Solubility: in water, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications

Product citations

  1. Bunce, C.; Barske, L.; Zhang, G.; Capel, B. Biased Precursor Ingression Underlies the Center-to-Pole Pattern of Male Sex Determination in Mouse. Development, 2023, 150(5), dev201060. doi: 10.1242/dev.201060
  2. Jaiswal, R.K.; Lei, K.-H.; Chastain, M.; Wang, Y.; Shiva, O.; Li, S.; You, Z.; Chi, P.; Chai, W. CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection. Nature Communications, 2023, 14(1), 7882. doi: 10.1038/s41467-023-43685-2
  3. Chang, Y.-C.; Lin, K.; Baxley, R.M.; Durrett, W.; Wang, L.; Stojkova, O.; Billmann, M.; Ward, H.; Myers, C.L.; Bielinsky, A.-K. RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication. Open Biology, 2023, 13(8), 230068. doi: 10.1098/rsob.230068
  4. Shah, A.M.; Guo, L.; Morales, M.G.; Jaichander, P.; Chen, K.; Huang, H.; Cano Hernandez, K.; Xu, L.; Bassel-Duby, R.; Olson, E.N.; Liu, N. TWIST2-mediated chromatin remodeling promotes fusion-negative rhabdomyosarcoma. Science Advances, 2023, 9(17), eade8184. doi: 10.1126/sciadv.ade8184
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