EdU (5-ethynyl-2'-deoxyuridine)
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 10540 | 100 mg | $120.00 | in stock | |
| 20540 | 250 mg | $195.00 | in stock | |
| 30540 | 500 mg | $345.00 | in stock | |
| 40540 | 1 g |
$590.00
|
in stock |
EdU (ethynyldeoxyuridine) is a nucleoside, an analog of thymidine, carrying an ethynyl group. This nucleoside behaves as a substrate for cellular DNA replication machinery. Then, DNA containing ethynyl groups can be developed by Click chemistry reaction with various dye azides. Fluorescent DNA can be detected by microscopy, or cells can be sorted by FACS.
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General properties
| Appearance: | light beige to light brown solid |
| Molecular weight: | 252.22 |
| CAS number: | 61135-33-9 |
| Molecular formula: | C11H12N2O5 |
| Solubility: | good in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. |
| MSDS: | Download |
| Product specifications |
Product citations
- Wells, C.I.; Al-Ali, H.; Andrews, D.M.; Asquith, C.R.M.; Axtman, A.D.; Chung, M.; Dikic, I.; Ebner, D.; Elkins, J.M.; Ettmayer, P.; Fischer, C.; Frederiksen, M.; Gray, N.S.; Hatch, S.; Knapp, S.; Lee, S.; Lücking, U.; Michaelides, M.; Mills, C.E.; Müller, S.; Owen, D.; Picado, A.; Ramadan, K.; Saikatendu, K.S.; Schröder, M.; Stolz, A.; Tellechea, M.; Treiber, D.K.; Turunen, B.J.; Vilar, S.; Wang, J.; Zuercher, W.J.; Willson, T.M.; Drewry, D.H. The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification. bioRxiv, preprint. doi: 10.1101/2019.12.22.886523
- Gerosa, L.; Chidley, C.; Froehlich, F.; Sanchez, G.; Lim, S.K.; Muhlich, J.; Chen, J.-Y.; Baker, G.J.; Schapiro, D.; Shi, T.; Yi, L.; Nicora, C.D.; Claas, A.; Lauffenburger, D.A.; Qian, W.-J.; Wiley, H.S.; Sorger, P.K. Sporadic ERK pulses drive non-genetic resistance in drug-adapted BRAFV600E melanoma cells. bioRxiv, preprint. doi: 10.1101/762294
- Zahnreich, S.; Weber, B.; Rösch, G.; Schindler, D.; Schmidberger, H. Compromised repair of radiation-induced DNA double-strand breaks in Fanconi anemia fibroblasts in G2. DNA Repair, 2020, 96, 102992. doi: 10.1016/j.dnarep.2020.102992
- Agote-Aran, A.; Schmucker, S.; Jerabkova, K.; Jmel Boyer, I.; Berto, A.; Pacini, L.; Ronchi, P.; Kleiss, C.; Guerard, L.; Schwab, Y.; Moine, H.; Mandel, J.-L.; Jacquemont, S.; Bagni, C.; Sumara, I. Spatial control of nucleoporin condensation by fragile X-related proteins. EMBO Journal, 2020, 39(20), e104467. doi: 10.15252/embj.2020104467
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