Cyanine3 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 11020 | 1 mg |
$91
|
in stock | |
| 21020 | 5 mg |
$119
|
in stock | |
| 41020 | 25 mg |
$380
|
in stock | |
| 51020 | 50 mg |
$670
|
in stock | |
| 61020 | 100 mg |
$1150
|
5 days | |
| 81020 | 1 g |
please inquire
|
in stock |
Cyanine3 NHS ester is a reactive dye for the labeling of amino-groups in biomolecules, an analog of Cy3® NHS ester. This reagent is ideal for the labeling of soluble proteins, peptides, and oligonucleotides/DNA. For delicate proteins consider using water-soluble sulfo-Cyanine3 NHS ester which does not require use of any co-solvent.
Cyanine3 NHS ester is a replacement for NHS esters of Cy3® and DyLight 549.
Absorption and emission spectra of Cyanine3
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General properties
| Appearance: | red powder |
| Mass spec M+ increment: | 439.5 |
| Molecular weight: | 641.5 |
| CAS number: | 2632339-91-2 |
| Molecular formula: | C34H40N3BF4O4 |
| IUPAC name: | 3H-Indolium, 2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propen-1-yl]-1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-3,3-dimethyl-, tetrafluoroborate |
| Solubility: | poorly soluble in water (2.3 mM = 1.5 g/L), soluble in organic solvents (DMF, DMSO, dichloromethane) |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 555 |
| ε, L⋅mol−1⋅cm−1: | 150000 |
| Emission maximum, nm: | 570 |
| Fluorescence quantum yield: | 0.31 |
| CF260: | 0.04 |
| CF280: | 0.09 |
Product citations
- Oh, H. J.; Lee, Y.; Hwang, H.; Hong, K.; Choi, H.; Kang, J. Y.; Jung, Y. Size-Controlled Assembly of Phase Separated Protein Condensates with Interfacial Protein Cages. Nat Commun, 2025, 16(1), 1009. doi: 10.1038/s41467-025-56391-y
- Raik, S.; Aseyev, V.; Vuorimaa-Laukkanen, E.; Tavakoli, S.; Yetgin, C.; Laaksonen, T.; Urtti, A. Chitosan - Hyaluronate Based Polyplexes for the Delivery of Oligonucleotides: Structural Properties and Intravitreal Mobility. Carbohydrate Polymers, 2025, 366, 123920. doi: 10.1016/j.carbpol.2025.123920
- Elkhashab, M.; Barreto, G.; Fauconnier, M.; Le Bourlout, Y.; Creemers, L. B.; Nieminen, H. J.; Howard, K. A. ADAMTS5-Specific Gapmer Release from an Albumin Biomolecular Assembly and Cartilage Internalization Triggered by Ultrasound. Drug Delivery, 2025, 32(1), 2464921. doi: 10.1080/10717544.2025.2464921
- Feld, L. G.; Boehme, S. C.; Morad, V.; Sahin, Y.; Kaul, C. J.; Dirin, D. N.; Rainò, G.; Kovalenko, M. V. Quantifying Förster Resonance Energy Transfer from Single Perovskite Quantum Dots to Organic Dyes. ACS Nano, 2024, 18(14), 9997–10007. doi: 10.1021/acsnano.3c11359
Cy® is a trademark of Cytiva.
Short link - lumiprobe.com/sh/p/d
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