Cyanine3 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 11020 | 1 mg | $125.00 | in stock | |
| 21020 | 5 mg | $260.00 | in stock | |
| 41020 | 25 mg |
$510.00
|
in stock | |
| 51020 | 50 mg |
$895.00
|
in stock | |
| 61020 | 100 mg |
$1490.00
|
in stock |
Cyanine3 NHS ester is a reactive dye for the labeling of amino-groups in biomolecules, an analog of Cy3® NHS ester. This reagent is ideal for the labeling of soluble proteins, peptides, and oligonucleotides/DNA. For delicate proteins consider using water-soluble sulfo-Cyanine3 NHS ester which does not require use of any co-solvent.
Cyanine3 NHS ester is a replacement for NHS esters of Cy3® and DyLight 549.
Absorption and emission spectra of Cyanine3
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| Appearance: | red powder |
| Mass spec M+ increment: | 439.5 |
| Molecular weight: | 641.5 |
| CAS number: | 2632339-91-2 |
| Molecular formula: | C34H40N3BF4O4 |
| IUPAC name: | 3H-Indolium, 2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propen-1-yl]-1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-3,3-dimethyl-, tetrafluoroborate |
| Solubility: | poorly soluble in water (2.3 mM = 1.5 g/L), soluble in organic solvents (DMF, DMSO, dichloromethane) |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 555 |
| ε, L⋅mol−1⋅cm−1: | 150000 |
| Emission maximum, nm: | 570 |
| Fluorescence quantum yield: | 0.31 |
| CF260: | 0.04 |
| CF280: | 0.09 |
Product citations
- Zashikhina, N.; Gladnev, S.; Sharoyko, V.; Korzhikov-Vlakh, V.; Korzhikova-Vlakh, E.; Tennikova, T. Synthesis and Characterization of Nanoparticle-Based Dexamethasone-Polypeptide Conjugates as Potential Intravitreal Delivery Systems. International Journal of Molecular Sciences, 2023, 24(4), 3702. doi: 10.3390/ijms24043702
- Meiers, J.; Dastbaz, J.; Adam, S.; Rasheed, S.; Kirsch, S. H.; Meiser, P.; Gross, P.; Müller, R.; Titz, A. Pineapple Lectin AcmJRL Binds SARS-CoV-2 Spike Protein in a Carbohydrate-Dependent Fashion**. ChemBioChem, 2023, 24(3), e202200463. doi: 10.1002/cbic.202200463
- Khramtsov, Y. V.; Ulasov, A. V.; Rosenkranz, A. A.; Slastnikova, T. A.; Lupanova, T. N.; Georgiev, G. P.; Sobolev, A. S. An Approach to Evaluate the Effective Cytoplasmic Concentration of Bioactive Agents Interacting with a Selected Intracellular Target Protein. Pharmaceutics, 2023, 15(2), v. doi: 10.3390/pharmaceutics15020324
- Yi, G.; Sung, Y.; Kim, C.; Ra, J. S.; Hirakawa, H.; Kato, T. A.; Fujimori, A.; Kim, H.; Takata, K. DNA Polymerase θ-Mediated Repair of High LET Radiation-Induced Complex DNA Double-Strand Breaks. Nucleic Acids Research, 2023, 51(5), 2257–2269. doi: 10.1093/nar/gkad076
Cy® is a trademark of Cytiva.
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