Sulfo-Cyanine3 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 11320 | 1 mg | $110.00 | in stock | |
| 21320 | 5 mg | $290.00 | in stock | |
| 41320 | 25 mg |
$690.00
|
in stock | |
| 51320 | 50 mg |
$1270.00
|
in stock | |
| 61320 | 100 mg |
$1990.00
|
in stock |
Water soluble, amino-reactive sulfo-Cyanine3 NHS ester. Efficiently labels proteins and peptides in purely aqueous solution, without need for organic co-solvent. Ideal for proteins with low solubility, and proteins prone to denaturation.
This is sulfonated, hydrophilic and water-soluble dye. Non-sulfonated Cyanine3 NHS ester is also available.
This product is an analog of Cy3® NHS ester. Sulfo-Cyanine3 NHS ester replaces Cy3®, Alexa Fluor 546, and DyLight 549 for all applications.
Sulfo-Cyanine3 absorbance and emission spectra
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Water soluble sulfo-Cyanine5 fluorescent dye azide for Click Chemistry.Alkyne maleimide
Maleimide reagent for the attachment of alkyne functional group to proteins, peptides, and other molecules bearing SH (thiol) groups, including cysteine residues.Cyanine3 amine
Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.General properties
| Appearance: | dark red crystals |
| Molecular weight: | 735.80 |
| CAS number: | 1424150-38-8 (sodium salt); 1424433-17-9, 1518643-34-9 (inner salt) |
| Molecular formula: | C34H38N3NaO10S2 |
| IUPAC name: | 3H-Indolium, 2-[3-(1,3-dihydro-1,3,3-trimethyl-5-sulfo-2H-indol-2-ylidene)-1-propen-1-yl]-1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-3,3-dimethyl-5-sulfo-, inner salt, sodium salt |
| Solubility: | very high in water, good in polar organic solvents (DMF, DMSO) |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation maximum, nm: | 548 |
| ε, L⋅mol−1⋅cm−1: | 162000 |
| Emission maximum, nm: | 563 |
| Fluorescence quantum yield: | 0.1 |
| CF260: | 0.03 |
| CF280: | 0.06 |
Product citations
- Kam, A.; Loo, S.; Dutta, B.; Sze, S.K.; Tam, J.P. Plant-derived mitochondria-targeting cysteine-rich peptide modulates cellular bioenergetics. Journal of Biological Chemistry, 2019, 294(11), 4000–4011. doi: 10.1074/jbc.RA118.006693
- Cao, P.; Wei, X.; Awal, R.P.; Müller, R.; Wall, D. A Highly Polymorphic Receptor Governs Many Distinct Self-Recognition Types within the Myxococcales Order. mBio, 2019, 10, e02751-18. doi: 10.1128/mBio.02751-18
- Meena, G.G.; Jain, A.; Parks, J.; Stambaugh, A.; Patterson, J.; Hawkins, A.; Schmidt, H. Integration of sample preparation and analysis on an optofluidic chip for multi-target disease detection. Lab on a Chip, 2018, 18(23), 3678–3686. doi: 10.1039/c8lc00966j
- Zadeh, P.S.N.; do Valle Gomes, M.Z.; Abrahamsson, M.; Palmqvist, A.; Åkerman, B. Measuring Viscosity inside Mesoporous Silica Using Protein-Bound Molecular Rotor Probe. Physical Chemistry Chemical Physics, 2018, 20(36), 23202–23213. doi: 10.1039/C8CP01063C
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